Related references
Note: Only part of the references are listed.The influence of ceramide and its dihydro analog on the physico-chemical properties of sphingomyelin bilayers
Masanao Kinoshita et al.
CHEMISTRY AND PHYSICS OF LIPIDS (2020)
Obesity, Bioactive Lipids, and Adipose Tissue Inflammation in Insulin Resistance
Iwona Kojta et al.
NUTRIENTS (2020)
Dihydroceramides in Triglyceride-Enriched VLDL Are Associated with Nonalcoholic Fatty Liver Disease Severity in Type 2 Diabetes
Aurelie Carlier et al.
CELL REPORTS MEDICINE (2020)
Lipidomic profiling reveals early-stage metabolic dysfunction in overweight or obese humans
Aya Mousa et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS (2019)
Targeting a ceramide double bond improves insulin resistance and hepatic steatosis
Bhagirath Chaurasia et al.
SCIENCE (2019)
The role of dihydrosphingolipids in disease
Ruth. R. Magaye et al.
CELLULAR AND MOLECULAR LIFE SCIENCES (2019)
The role of C16:0 ceramide in the development of obesity and type 2 diabetes: CerS6 inhibition as a novel therapeutic approach
Suryaprakash Raichur et al.
MOLECULAR METABOLISM (2019)
Specific Hepatic Sphingolipids Relate to Insulin Resistance, Oxidative Stress, and Inflammation in Nonalcoholic Steatohepatitis
Maria Apostolopoulou et al.
DIABETES CARE (2018)
Dihydroceramide Desaturase 1 Inhibitors Reduce Amyloid-β Levels in Primary Neurons from an Alzheimer's Disease Transgenic Model
Lara Ordonez-Gutierrez et al.
PHARMACEUTICAL RESEARCH (2018)
Lipid environment induces ER stress, TXNIP expression and inflammation in immune cells of individuals with type 2 diabetes
Anais Szpigel et al.
DIABETOLOGIA (2018)
Gamma-tocotrienol profoundly alters sphingolipids in cancer cells by inhibition of dihydroceramide desaturase and possibly activation of sphingolipid hydrolysis during prolonged treatment
Yumi Jang et al.
JOURNAL OF NUTRITIONAL BIOCHEMISTRY (2017)
Sphingolipids and Lipoproteins in Health and Metabolic Disorders
Jahangir Iqbal et al.
TRENDS IN ENDOCRINOLOGY AND METABOLISM (2017)
Roles of Diacylglycerols and Ceramides in Hepatic Insulin Resistance
Max C. Petersen et al.
TRENDS IN PHARMACOLOGICAL SCIENCES (2017)
Plasma Dihydroceramides Are Diabetes Susceptibility Biomarker Candidates in Mice and Humans
Leonore Wigger et al.
CELL REPORTS (2017)
Dihydroceramide is a key metabolite that regulates autophagy and promotes fibrosis in hepatic steatosis model
Ah Young Lee et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2017)
Steatosis and NASH in type 2 diabetes
Mengyue Hu et al.
BIOCHIMIE (2017)
Phosphoglycerol dihydroceramide, a distinctive ceramide produced by Porphyromonas gingivalis, promotes RANKL-induced osteoclastogenesis by acting on non-muscle myosin II-A (Myh9), an osteoclast cell fusion regulatory factor
Hiroyuki Kanzaki et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS (2017)
Sphingolipids Contribute to Human Atherosclerotic Plaque Inflammation
Andreas Edsfeldt et al.
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2016)
Dihydroceramide accumulation mediates cytotoxic autophagy of cancer cells via autolysosome destabilization
Sonia Hernandez-Tiedra et al.
AUTOPHAGY (2016)
Adipocyte Ceramides Regulate Subcutaneous Adipose Browning, Inflammation, and Metabolism
Bhagirath Chaurasia et al.
Cell Metabolism (2016)
Hepatic ceramides dissociate steatosis and insulin resistance in patients with non-alcoholic fatty liver disease
Panu K. Luukkonen et al.
JOURNAL OF HEPATOLOGY (2016)
Enhanced apoptotic cancer cell killing after Foscan photodynamic therapy combined with fenretinide via de novo sphingolipid biosynthesis pathway
Nithin B. Boppana et al.
JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY (2016)
Targeting sphingolipid metabolism in the treatment of obesity/type 2 diabetes
Lara Bellini et al.
EXPERT OPINION ON THERAPEUTIC TARGETS (2015)
Dihydroceramides: From Bit Players to Lead Actors
Monowarul Mobin Siddique et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2015)
Vitamin E γ-Tocotrienol Inhibits Cytokine-Stimulated NF-κB Activation by Induction of Anti-Inflammatory A20 via Stress Adaptive Response Due to Modulation of Sphingolipids
Yun Wang et al.
JOURNAL OF IMMUNOLOGY (2015)
The Sphingosine Kinase 2 Inhibitor ABC294640 Reduces the Growth of Prostate Cancer Cells and Results in Accumulation of Dihydroceramides In Vitro and In Vivo
Heather Venant et al.
MOLECULAR CANCER THERAPEUTICS (2015)
LIPOPOLYSACCHARIDE DISRUPTS MITOCHONDRIAL PHYSIOLOGY IN SKELETAL MUSCLE VIA DISPARATE EFFECTS ON SPHINGOLIPID METABOLISM
Melissa E. Hansen et al.
SHOCK (2015)
Increased Dihydroceramide/Ceramide Ratio Mediated by Defective Expression of degs1 Impairs Adipocyte Differentiation and Function
Nuria Barbarroja et al.
DIABETES (2015)
Obesity-Induced CerS6-Dependent C16:0 Ceramide Production Promotes Weight Gain and Glucose Intolerance
Sarah M. Turpin et al.
CELL METABOLISM (2014)
Inhibition of ceramide de novo synthesis reduces liver lipid accumulation in rats with nonalcoholic fatty liver disease
Krzysztof Kurek et al.
LIVER INTERNATIONAL (2014)
Plasma Dihydroceramide Species Associate with Waist Circumference in Mexican American Families
Manju Mamtani et al.
OBESITY (2014)
Characterising the Inhibitory Actions of Ceramide upon Insulin Signaling in Different Skeletal Muscle Cell Models: A Mechanistic Insight
Rana Mahfouz et al.
PLOS ONE (2014)
A sphingosine kinase inhibitor combined with temozolomide induces glioblastoma cell death through accumulation of dihydrosphingosine and dihydroceramide, endoplasmic reticulum stress and autophagy
J. Noack et al.
CELL DEATH & DISEASE (2014)
Defect of insulin signal in peripheral tissues: important role of ceramide
Rima Hage Hassan et al.
WORLD JOURNAL OF DIABETES (2014)
Ceramides Contained in LDL Are Elevated in Type 2 Diabetes and Promote Inflammation and Skeletal Muscle Insulin Resistance
James Boon et al.
DIABETES (2013)
Distinct patterns of tissue-specific lipid accumulation during the induction of insulin resistance in mice by high-fat feeding
N. Turner et al.
DIABETOLOGIA (2013)
Regulation of De Novo Ceramide Synthesis: The Role of Dihydroceramide Desaturase and Transcriptional Factors NFATC and Hand2 in the Hypoxic Mouse Heart
Raed Azzam et al.
DNA AND CELL BIOLOGY (2013)
Plasma sphingolipids are biomarkers of metabolic syndrome in non-human primates maintained on a Western-style diet
J. T. Brozinick et al.
INTERNATIONAL JOURNAL OF OBESITY (2013)
Plasma ceramides are elevated in female children and adolescents with type 2 diabetes
Ximena Lopez et al.
JOURNAL OF PEDIATRIC ENDOCRINOLOGY & METABOLISM (2013)
Ablation of Dihydroceramide Desaturase 1, a Therapeutic Target for the Treatment of Metabolic Diseases, Simultaneously Stimulates Anabolic and Catabolic Signaling
Monowarul M. Siddique et al.
MOLECULAR AND CELLULAR BIOLOGY (2013)
Fenretinide Causes Emphysema, Which Is Prevented by Sphingosine 1-Phoshate
Masanori Yasuo et al.
PLOS ONE (2013)
C22:0-and C24:0-dihydroceramides Confer Mixed Cytotoxicity in T-Cell Acute Lymphoblastic Leukemia Cell Lines
Michael W. Holliday et al.
PLOS ONE (2013)
Dihydroceramide accumulation and reactive oxygen species are distinct and nonessential events in 4-HPR-mediated leukemia cell death
Aintzane Apraiz et al.
BIOCHEMISTRY AND CELL BIOLOGY-BIOCHIMIE ET BIOLOGIE CELLULAIRE (2012)
Dihydroceramide delays cell cycle G1/S transition via activation of ER stress and induction of autophagy
Vincenzo Gagliostro et al.
INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY (2012)
Fenretinide Prevents Lipid-induced Insulin Resistance by Blocking Ceramide Biosynthesis
Benjamin T. Bikman et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2012)
Dihydroceramide-based Response to Hypoxia
Cecilia M. Devlin et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
Phosphorylated Dihydroceramides from Common Human Bacteria Are Recovered in Human Tissues
Frank C. Nichols et al.
PLOS ONE (2011)
Dihydroceramide desaturase activity is modulated by oxidative stress
Jolanta Idkowiak-Baldys et al.
BIOCHEMICAL JOURNAL (2010)
Dihydrosphingomyelin Impairs HIV-1 Infection by Rigidifying Liquid-Ordered Membrane Domains
Catarina R. Vieira et al.
CHEMISTRY & BIOLOGY (2010)
Mammalian Ceramide Synthases
Michal Levy et al.
IUBMB LIFE (2010)
Unique Lipids from a Common Human Bacterium Represent a New Class of Toll-Like Receptor 2 Ligands Capable of Enhancing Autoimmunity
Frank C. Nichols et al.
AMERICAN JOURNAL OF PATHOLOGY (2009)
Dihydroceramide intracellular increase in response to resveratrol treatment mediates autophagy in gastric cancer cells
Paola Signorelli et al.
CANCER LETTERS (2009)
The selective COX-2 inhibitor celecoxib modulates sphingolipid synthesis
Susanne Schiffmann et al.
JOURNAL OF LIPID RESEARCH (2009)
Targeting of PKCζ and PKB to caveolin-enriched microdomains represents a crucial step underpinning the disruption in PKB-directed signalling by ceramide
Eric Hajduch et al.
BIOCHEMICAL JOURNAL (2008)
The PERK/eIF2α signaling pathway of Unfolded Protein Response is essential for N-(4-hydroxyphenyl)retinamide (4HPR)-induced cytotoxicity in cancer cells
Wai-Lung Lai et al.
EXPERIMENTAL CELL RESEARCH (2008)
Lipid Mediators of Insulin Resistance
William L. Holland et al.
NUTRITION REVIEWS (2008)
Modulation of total ceramide and constituent ceramide species in the acutely and chronically hypoxic mouse heart at different ages
Lama Noureddine et al.
PROSTAGLANDINS & OTHER LIPID MEDIATORS (2008)
Characterization of ceramide synthase 2 - Tissue distribution, substrate specificity, and inhibition by sphingosine 1-phosphate
Elad L. Laviad et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
Adipose tissue inflammation and increased ceramide content characterize subjects with high liver fat content independent of obesity
Maria Kolak et al.
DIABETES (2007)
Metabolic endotoxemia initiates obesity and insulin resistance
Patrice D. Cani et al.
DIABETES (2007)
Involvement of dihydroceramide desaturase in cell cycle progression in human neuroblastoma cells
Jacqueline M. Kraveka et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
Ceramides and other bioactive sphingolipid backbones in health and disease: Lipidomic analysis, metabolism and roles in membrane structure, dynamics, signaling and autophagy
Wenjing Zheng et al.
BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES (2006)
Dihydroceramide hinders ceramide channel formation: Implications on apoptosis
J. Stiban et al.
APOPTOSIS (2006)
The 4,5-double bond of ceramide regulates its dipole potential, elastic properties, and packing behavior
HL Brockman et al.
BIOPHYSICAL JOURNAL (2004)
Identification and characterization of a sphingolipid Δ4-desaturase family
P Ternes et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Ceramide impairs the insulin-dependent membrane recruitment of Protein Kinase B leading to a loss in downstream signalling in L6 skeletal muscle cells
E Hajduch et al.
DIABETOLOGIA (2001)
Share Paper
