4.8 Article

Boron Quantum Dots for Photoacoustic Imaging-Guided Photothermal Therapy

Journal

ACS APPLIED MATERIALS & INTERFACES
Volume 13, Issue 1, Pages 306-311

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/acsami.0c21198

Keywords

boron quantum dots; theranostic agents; photoacoustic imaging; photothermal therapy

Funding

  1. National Natural Science Foundation of China [21904018]
  2. Natural Science Foundation of Fujian Province of China [2018J01896, 2020J01861]
  3. Joint Funds for the Innovation of Science and Technology, Fujian Province [2017Y9041]
  4. Scientific Foundation of Fujian Provincial Health Commission [2018-ZQN-37, 2016-1-44]
  5. Scientific Research Starting Foundation Project of Fujian University of Technology [E0600428]

Ask authors/readers for more resources

Photothermal therapy is a promising new tumor treatment method, and the study found that the synthesized boron quantum dots have excellent biological safety and high photothermal conversion ability, making them suitable for tumor photothermal therapy applications.
Photothermal therapy is a new type of tumor therapy with great potential. An ideal photothermal therapy agent should have high photothermal conversion effect, low biological toxicity, and degradability. The development of novel photothermal therapy agents with these properties is of great demand. In this study, we synthesized boron quantum dots (BQDs) with an ultrasmall hydrodynamic diameter. Both in vitro and in vivo studies show that the as-synthesized BQDs have good biological safety, high photoacoustic imaging performance, and photothermal conversion ability, which can be used for photoacoustic imaging-guided photothermal agents for tumor treatment. Our investigations confirm that the BQDs hold great promise in tumor theranostic applications.

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