Effect of side chain phenyl group on the self-assembled morphology of dipeptide hydrazides

We report self-assembled nanostructures of dipeptides hydrazides, in which alanine and/or phenylalanine are employed as components to investigate the effect of the side chain phenyl group on the morphology of self-assembled nanostructures. We demonstrated that the dimensions of the self-assembled nanostructures can vary from 1D (fiber and tubular) to 2D (sheet) solely by adjusting the position of the side chain phenyl group in the simple molecular scaffold of the dipeptide hydrazides. This study highlights the significance and potential of systematic investigations for finetuning the morphology of aqueous self-assembled structures of the dipeptide hydrazides with the aim of exploring functional soft nanomaterials.

Automated summary

By adjusting the position of the side chain phenyl group, the dimensions and morphology of self-assembled nanostructures of dipeptide hydrazides can be changed, highlighting the significance of systematic investigations in exploring functional soft nanomaterials.