Journal
CURRENT OPINION IN ELECTROCHEMISTRY
Volume 23, Issue -, Pages 1-6Publisher
ELSEVIER
DOI: 10.1016/j.coelec.2020.02.013
Keywords
Paper-based microfluidics; Electrochemical detection; Electrochemical paper-based analytical devices; Microfluidics
Funding
- National Science Foundation [CHE-1710222]
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The growing need for reliable analytical tools to perform measurements at the point-of-need has prompted the development of novel sensors that are low cost, portable, sensitive, easy to use, and capable of multiplexed analysis. Miniaturization of the sensors into microfluidic platforms has become a promising approach to achieve these self-contained sensors. However, traditional microfluidics often require relatively expensive and complicated pumping mechanisms that increase the cost and limit the portability of the sensors. From a material perspective, paper is an attractive substrate for constructing point-of-need sensors because of its affordability, vast availability, and self-pumping ability, particularly when combined with electrochemical detection. In this mini-review, we discuss various strategies to achieve multiplexing or simultaneous detection of multiple analytes in electrochemical paper-based devices and provide a brief guide on selecting the detection strategy based on the electrochemical property of the analytes.
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