4.4 Article

Serological investigations of Peste des Petits Ruminants in cattle of Nepal

Journal

VETERINARY MEDICINE AND SCIENCE
Volume 7, Issue 1, Pages 122-126

Publisher

WILEY
DOI: 10.1002/vms3.354

Keywords

cattle; Nepal; PPR; seroprevalence

Funding

  1. National Key Research and Development Program of China [2016YFD0500108, 2016YFE0204100]
  2. International Cooperation Project of CAAS Innovation Program [CAAS-GJHZ201700X]

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The study in Nepal found a 5.88% prevalence of PPRV antibodies in cattle, indicating their exposure to the PPR virus. Intensive monitoring of both domestic and wild animals is crucial for effective disease control programs.
Peste des Petits Ruminant (PPR) is an infectious viral disease of small ruminants caused by PPR virus. Although goat and sheep are the primary hosts of PPR, studies have continuously reported the prevalence of circulating antibodies in large ruminants, which could bring a potential challenge to effectively control and eradicate PPR. In Nepal, seroprevalence of PPRV antibodies in cattle have not been monitored yet. To address this, a total of 255 cattle sera were collected from Rupandehi, Banke, Bara and Chitwan districts of Nepal where outbreak of PPR in small ruminants was reported previously. The sera samples were tested by competitive ELISA and the result indicated the prevalence of 5.88% PPRV antibodies in cattle which indicates the exposure of cattle to PPR virus. To make the disease control program effective, intensive monitoring of both domestic and wild animals is very important.

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