Journal
GENERAL THORACIC AND CARDIOVASCULAR SURGERY
Volume 69, Issue 4, Pages 662-672Publisher
SPRINGER JAPAN KK
DOI: 10.1007/s11748-020-01501-4
Keywords
Tricuspid regurgitation; Tricuspid annuloplasty; Right ventricular function
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Funding
- Edwards Lifesciences Corporation
- Medtronic Japan Co., Ltd.
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This study aimed to investigate the impact of tricuspid annuloplasty concomitant with left-sided valve surgery on right ventricular function in patients with mild or more tricuspid regurgitation. The results showed that adding tricuspid annuloplasty may potentially achieve recovery in RV dimension and function, which was not obtained with left-sided valve surgery alone.
Background To elucidate the impact of tricuspid annuloplasty concomitant with left-sided valve surgery on the right ventricular (RV) function in patients with mild or more tricuspid regurgitation (TR). Methods We enrolled 136 patients with mild or more TR who underwent left-sided valve surgery. Seventy-three patients underwent left-sided valve surgery alone (group non-T) and 63 underwent concomitant tricuspid annuloplasty (group T). The echocardiographic data at the latest follow-up (mean 1019 days) were compared using multiple regression analysis to adjust cofounding factors. Propensity score was calculated and included in the analysis as a covariate. In addition, propensity score matching was used for sensitive analysis (12 pairs). Results In group non-T, there were more aortic valve surgeries, and fewer mitral valve surgeries. At baseline, body surface area, New York Heart Association class, and prevalence of atrial fibrillation were significantly different between groups. On preoperative echocardiography, left and right atrial diameter, RV diameter, and tricuspid annular diameter were larger in group T, whereas there was no significant difference in RV fractional area change. In multiple regression analyses, RV diameter in diastole was significantly lower and RV fractional area change was significantly higher at the follow-up period in group T. These results were not attenuated even in subgroup analysis in patients with only mild TR or mitral valve surgery alone. Conclusion Among patients with mild or more TR, RV dimensional and functional recovery was not obtained with left-sided valve surgery alone. Adding tricuspid annuloplasty may potentially achieve both outcomes.
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