4.5 Article

The Role of Eating Behaviours in Genetic Susceptibility to Obesity

Journal

CURRENT OBESITY REPORTS
Volume 9, Issue 4, Pages 512-521

Publisher

SPRINGER
DOI: 10.1007/s13679-020-00402-0

Keywords

CEBQ; Appetite; Appetitive traits; Eating behaviours; Genetics; Obesity; Twin studies; Polygenic risk scores; Behavioural susceptibility

Funding

  1. Medical Research Council UK [MR/T027843/1]
  2. Advanced Quantitative Methods Studentship from the Economic Social Research Council (ESRC)
  3. MRC [MR/T027843/1] Funding Source: UKRI

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Purpose of Review Eating behaviours are hypothesised to be the behavioural expression of genetic risk of obesity. In this review, we summarise findings from behavioural genetic research on the association between genetic risk for obesity and validated psychometrics measures of eating behaviours in children and adults (published in the past 10 years). Recent Findings Twin studies have produced some evidence for a shared genetic aetiology underlying body mass index and eating behaviours. Studies using measured genetic susceptibility to obesity have suggested that increased genetic liability for obesity is associated with variation in obesogenic eating behaviours such as emotional and uncontrolled eating. More research on this topic is needed. Especially longitudinal studies using genetically sensitive designs to investigate the direction of genetic pathways between genetic liability of eating behaviours to weight and vice versa, as well as the potential subsequent link to eating disorders.

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