Related references
Note: Only part of the references are listed.New genetic signals for lung function highlight pathways and chronic obstructive pulmonary disease associations across multiple ancestries
Nick Shrine et al.
NATURE GENETICS (2019)
A genome-wide association analysis identifies 16 novel susceptibility loci for carpal tunnel syndrome
Akira Wiberg et al.
NATURE COMMUNICATIONS (2019)
Trans-ethnic association study of blood pressure determinants in over 750,000 individuals
Ayush Giri et al.
NATURE GENETICS (2019)
FBLN3 inhibits the invasion and metastasis of colorectal cancer through the AKT/mTOR pathway
H. Y. Mao et al.
NEOPLASMA (2019)
Genome-wide association analyses identify new loci influencing intraocular pressure
X. Raymond Gao et al.
HUMAN MOLECULAR GENETICS (2018)
Genome-wide association study of intraocular pressure uncovers new pathways to glaucoma
Stuart MacGregor et al.
NATURE GENETICS (2018)
IUPred2A: context-dependent prediction of protein disorder as a function of redox state and protein binding
Balint Meszaros et al.
NUCLEIC ACIDS RESEARCH (2018)
Extracellular Interactions between Fibulins and Transforming Growth Factor (TGF)-β in Physiological and Pathological Conditions
Takeshi Tsuda
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2018)
Genome-wide association analyses identify 39 new susceptibility loci for diverticular disease
Lillias H. Maguire et al.
NATURE GENETICS (2018)
A genome-wide association study identifies a susceptibility locus for biliary atresia on 2p16.1 within the gene EFEMP1
Ying Chen et al.
PLOS GENETICS (2018)
Development of a Function-Blocking Antibody Against Fibulin-3 as a Targeted Reagent for Glioblastoma
Mohan S. Nandhu et al.
CLINICAL CANCER RESEARCH (2018)
New insights into the genetics of primary open-angle glaucoma based on meta-analyses of intraocular pressure and optic disc characteristics
Henriet Springelkamp et al.
HUMAN MOLECULAR GENETICS (2017)
Tumor-derived fibulin-3 activates pro-invasive NF-κB signaling in glioblastoma cells and their microenvironment
M. S. Nandhu et al.
ONCOGENE (2017)
A large multi-ethnic genome-wide association study identifies novel genetic loci for intraocular pressure
Helene Choquet et al.
NATURE COMMUNICATIONS (2017)
Genome-wide association and HLA region fine-mapping studies identify susceptibility loci for multiple common infections
Chao Tian et al.
NATURE COMMUNICATIONS (2017)
Impact of interaction between the G870A and EFEMP1 gene polymorphism on glioma risk in Chinese Han population
Libin Yang et al.
ONCOTARGET (2017)
Genome-wide association analysis for chronic venous disease identifies EFEMP1 and KCNH8 as susceptibility loci
Eva Ellinghaus et al.
SCIENTIFIC REPORTS (2017)
Fibulin-3 promotes osteosarcoma invasion and metastasis by inducing epithelial to mesenchymal transition and activating the Wnt/β-catenin signaling pathway
Songgang Wang et al.
SCIENTIFIC REPORTS (2017)
MiR-338-5p suppresses proliferation, migration, invasion, and promote apoptosis of glioblastoma cells by directly targeting EFEMP1
Deqiang Lei et al.
BIOMEDICINE & PHARMACOTHERAPY (2017)
Mapping wild-type and R345W fibulin-3 intracellular interactomes
John D. Hulleman et al.
EXPERIMENTAL EYE RESEARCH (2016)
Identification of Genes Associated with Papillary Thyroid Carcinoma (PTC) for Diagnosis by Integrated Analysis
W. -B. Li et al.
HORMONE AND METABOLIC RESEARCH (2016)
Dancing Protein Clouds: The Strange Biology and Chaotic Physics of Intrinsically Disordered Proteins
Vladimir N. Uversky
JOURNAL OF BIOLOGICAL CHEMISTRY (2016)
Detection and interpretation of shared genetic influences on 42 human traits
Joseph K. Pickrell et al.
NATURE GENETICS (2016)
EFEMP1 inhibits migration of hepatocellular carcinoma by regulating MMP2 and MMP9 via ERK1/2 activity
Cheng-Yun Dou et al.
ONCOLOGY REPORTS (2016)
Genome-wide association studies in East Asians identify new loci for waist-hip ratio and waist circumference
Wanqing Wen et al.
SCIENTIFIC REPORTS (2016)
Assessment of polygenic effects links primary open-angle glaucoma and age-related macular degeneration
Gabriel Cuellar-Partida et al.
SCIENTIFIC REPORTS (2016)
Functional roles of transiently and intrinsically disordered regions within proteins
Vladimir N. Uversky
FEBS JOURNAL (2015)
Meta-analysis of Genome-Wide Association Studies Identifies Novel Loci Associated With Optic Disc Morphology
Henriet Springelkamp et al.
GENETIC EPIDEMIOLOGY (2015)
Fibulin-3 is a novel TGF-β pathway inhibitor in the breast cancer microenvironment
H. Tian et al.
ONCOGENE (2015)
A genome-wide association study identifies four novel susceptibility loci underlying inguinal hernia
Eric Jorgenson et al.
NATURE COMMUNICATIONS (2015)
EFEMP1 promotes the migration and invasion of osteosarcoma via MMP-2 with induction by AEG-1 via NF-κB signaling pathway
Zhuo Wang et al.
ONCOTARGET (2015)
p38 MAPK Down-regulates Fibulin 3 Expression through Methylation of Gene Regulatory Sequences ROLE IN MIGRATION AND INVASION
Maria Arechederra et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2015)
Intrinsically Disordered Proteins and Intrinsically Disordered Protein Regions
Christopher J. Oldfield et al.
ANNUAL REVIEW OF BIOCHEMISTRY, VOL 83 (2014)
Novel Paracrine Modulation of Notch-DLL4 Signaling by Fibulin-3 Promotes Angiogenesis in High-Grade Gliomas
Mohan S. Nandhu et al.
CANCER RESEARCH (2014)
Fibulin-3 suppresses Wnt/β-catenin signaling and lung cancer invasion
Xiaojun Chen et al.
CARCINOGENESIS (2014)
Pathological Unfoldomics of Uncontrolled Chaos: Intrinsically Disordered Proteins and Human Diseases
Vladimir N. Uversky et al.
CHEMICAL REVIEWS (2014)
Introducing Protein Intrinsic Disorder
Johnny Habchi et al.
CHEMICAL REVIEWS (2014)
Classification of Intrinsically Disordered Regions and Proteins
Robin van der Lee et al.
CHEMICAL REVIEWS (2014)
Epigenetic regulation of EFEMP1 in prostate cancer: biological relevance and clinical potential
Mafalda Almeida et al.
JOURNAL OF CELLULAR AND MOLECULAR MEDICINE (2014)
Novel tumor-suppressor gene epidermal growth factor-containing fibulin-like extracellular matrix protein 1 is epigenetically silenced and associated with invasion and metastasis in human gastric cancer
Xin-Jiang Zhu et al.
MOLECULAR MEDICINE REPORTS (2014)
Genome-wide association analysis identifies six new loci associated with forced vital capacity
Daan W. Loth et al.
NATURE GENETICS (2014)
Defining the role of common variation in the genomic and biological architecture of adult human height
Andrew R. Wood et al.
NATURE GENETICS (2014)
The MIntAct project-IntAct as a common curation platform for 11 molecular interaction databases
Sandra Orchard et al.
NUCLEIC ACIDS RESEARCH (2014)
Role of fibulin-3 in lung cancer: In vivo and in vitro analyses
Shun Xu et al.
ONCOLOGY REPORTS (2014)
The structural and functional signatures of proteins that undergo multiple events of post-translational modification
Vikas Pejaver et al.
PROTEIN SCIENCE (2014)
Unusual biophysics of intrinsically disordered proteins
Vladimir N. Uversky
BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS (2013)
Alternative splicing of intrinsically disordered regions and rewiring of protein interactions
Marija Buljan et al.
CURRENT OPINION IN STRUCTURAL BIOLOGY (2013)
Exon-level expression profiling of ocular tissues
Alex H. Wagner et al.
EXPERIMENTAL EYE RESEARCH (2013)
Metformin inhibits glioma cell U251 invasion by downregulation of fibulin-3
Lian-Bo Gao et al.
NEUROREPORT (2013)
(DP2)-P-2: database of disordered protein predictions
Matt E. Oates et al.
NUCLEIC ACIDS RESEARCH (2013)
Epigenetic Inactivation of EFEMP1 Is Associated with Tumor Suppressive Function in Endometrial Carcinoma
Tingting Yang et al.
PLOS ONE (2013)
Decrease of Fibulin-3 in Hepatocellular Carcinoma Indicates Poor Prognosis
Rongzhen Luo et al.
PLOS ONE (2013)
Overexpression of EFEMP1 Correlates with Tumor Progression and Poor Prognosis in Human Ovarian Carcinoma
Jie Chen et al.
PLOS ONE (2013)
A decade and a half of protein intrinsic disorder: Biology still waits for physics
Vladimir N. Uversky
PROTEIN SCIENCE (2013)
ESpritz: accurate and fast prediction of protein disorder
Ian Walsh et al.
BIOINFORMATICS (2012)
Effect of metformin on survival outcomes in diabetic patients with triple receptor-negative breast cancer
Soley Bayraktar et al.
CANCER (2012)
Metformin Inhibits Cell Proliferation, Migration and Invasion by Attenuating CSC Function Mediated by Deregulating miRNAs in Pancreatic Cancer Cells
Bin Bao et al.
CANCER PREVENTION RESEARCH (2012)
Fibulin-3 Promotes Glioma Growth and Resistance through a Novel Paracrine Regulation of Notch Signaling
Bin Hu et al.
CANCER RESEARCH (2012)
Metformin Use Is Associated with Better Survival of Diabetic Patients with Pancreatic Cancer
Navid Sadeghi et al.
CLINICAL CANCER RESEARCH (2012)
Tissue-Specific Splicing of Disordered Segments that Embed Binding Motifs Rewires Protein Interaction Networks
Marija Buljan et al.
MOLECULAR CELL (2012)
CDH13 and FLBN3 Gene Methylation are Associated with Poor Prognosis in Colorectal Cancer
Zhu Wang et al.
PATHOLOGY & ONCOLOGY RESEARCH (2012)
Intrinsically disordered proteins: a 10-year recap
Peter Tompa
TRENDS IN BIOCHEMICAL SCIENCES (2012)
EFEMP1 as a Novel DNA Methylation Marker for Prostate Cancer: Array-Based DNA Methylation and Expression Profiling
Yong-June Kim et al.
CLINICAL CANCER RESEARCH (2011)
Genetics of anterior segment dysgenesis disorders
Linda M. Reis et al.
CURRENT OPINION IN OPHTHALMOLOGY (2011)
Biological role of matrix metalloproteinases: a critical balance
S. Loeffek et al.
EUROPEAN RESPIRATORY JOURNAL (2011)
Adult height variants affect birth length and growth rate in children
Lavinia Paternoster et al.
HUMAN MOLECULAR GENETICS (2011)
Gene expression signatures differentiate ovarian/peritoneal serous carcinoma from breast carcinoma in effusions
Ben Davidson et al.
JOURNAL OF CELLULAR AND MOLECULAR MEDICINE (2011)
Matrix Metalloproteinase Imbalance in Inguinal Hernia Formation
George A. Antoniou et al.
JOURNAL OF INVESTIGATIVE SURGERY (2011)
Downregulation of fibulin-3 gene by promoter methylation in colorectal cancer predicts adverse prognosis
J. D. Tong et al.
NEOPLASMA (2011)
The STRING database in 2011: functional interaction networks of proteins, globally integrated and scored
Damian Szklarczyk et al.
NUCLEIC ACIDS RESEARCH (2011)
Genome-Wide Association Study of Anthropometric Traits and Evidence of Interactions With Age and Study Year in Filipino Women
Damien C. Croteau-Chonka et al.
OBESITY (2011)
Elasticity-Dependent Modulation of TGF-β Responses in Human Trabecular Meshwork Cells
Hong Han et al.
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE (2011)
Epidermal Growth Factor-Containing Fibulin-Like Extracellular Matrix Protein 1, EFEMP1, a Novel Tumor-Suppressor Gene Detected in Hepatocellular Carcinoma Using Double Combination Array Analysis
Shuji Nomoto et al.
ANNALS OF SURGICAL ONCOLOGY (2010)
Fibulin-3 negatively regulates chondrocyte differentiation
Toru Wakabayashi et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2010)
PONDR-FIT: A meta-predictor of intrinsically disordered amino acids
Bin Xue et al.
BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS (2010)
Understanding protein non-folding
Vladimir N. Uversky et al.
BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS (2010)
The role of height-associated loci identified in genome wide association studies in the determination of pediatric stature
Jianhua Zhao et al.
BMC MEDICAL GENETICS (2010)
The expression of EFEMP1 in cervical carcinoma and its relationship with prognosis
Song En-lin et al.
GYNECOLOGIC ONCOLOGY (2010)
A genome-wide association study in 19 633 Japanese subjects identified LHX3-QSOX2 and IGF1 as adult height loci
Yukinori Okada et al.
HUMAN MOLECULAR GENETICS (2010)
Fibulin-3 is associated with tumour progression and a poor prognosis in nasopharyngeal carcinomas and inhibits cell migration and invasion via suppressed AKT activity
Chung-Feng Hwang et al.
JOURNAL OF PATHOLOGY (2010)
Aberrant promoter methylation of FBLN-3 gene and clinicopathological significance in non-small cell lung carcinoma
Wang Rui et al.
LUNG CANCER (2010)
Hundreds of variants clustered in genomic loci and biological pathways affect human height
Hana Lango Allen et al.
NATURE (2010)
Identification of a Preneoplastic Gene Expression Profile in Tubal Epithelium of BRCA1 Mutation Carriers
Joshua Z. Press et al.
NEOPLASIA (2010)
ANCHOR: web server for predicting protein binding regions in disordered proteins
Zsuzsanna Dosztanyi et al.
BIOINFORMATICS (2009)
Decreased expression of angiogenesis antagonist EFEMP1 in sporadic breast cancer is caused by aberrant promoter methylation and points to an impact of EFEMP1 as molecular biomarker
Ariane Sadr-Nabavi et al.
INTERNATIONAL JOURNAL OF CANCER (2009)
Fibulin-3 Is Uniquely Upregulated in Malignant Gliomas and Promotes Tumor Cell Motility and Invasion
Bin Hu et al.
MOLECULAR CANCER RESEARCH (2009)
A large-scale genome-wide association study of Asian populations uncovers genetic factors influencing eight quantitative traits
Yoon Shin Cho et al.
NATURE GENETICS (2009)
ECM1 interacts with fibulin-3 and the beta 3 chain of laminin 332 through its serum albumin subdomain-like 2 domain
S. Sercu et al.
MATRIX BIOLOGY (2009)
Differential Expression of Fibulin Family Proteins in the Para-cervical Weak Zone and Other Areas of Human Fetal Membranes
R. M. Moore et al.
PLACENTA (2009)
Prediction of Protein Binding Regions in Disordered Proteins
Balint Meszaros et al.
PLOS COMPUTATIONAL BIOLOGY (2009)
Intrinsically disordered proteins in human diseases: Introducing the D-2 concept
Vladimir N. Uversky et al.
ANNUAL REVIEW OF BIOPHYSICS (2008)
Extracellular matrix in the trabecular meshwork
Ted S. Acott et al.
EXPERIMENTAL EYE RESEARCH (2008)
Genome-wide association analysis identifies 20 loci that influence adult height
Michael N. Weedon et al.
NATURE GENETICS (2008)
Many sequence variants affecting diversity of adult human height
Daniel F. Gudbjartsson et al.
NATURE GENETICS (2008)
Lack of fibulin-3 causes early aging and herniation, but not macular degeneration in mice
Precious J. McLaughlin et al.
HUMAN MOLECULAR GENETICS (2007)
Mining α-helix-forming molecular recognition features with cross species sequence alignments
Yugong Cheng et al.
BIOCHEMISTRY (2007)
Frequent inactivation of RAMP2, EFEMP1 and Dutt1 in lung cancer by promoter hypermethylation
Wen Yue et al.
CLINICAL CANCER RESEARCH (2007)
Signal integration in the endoplasmic reticulum unfolded protein response
David Ron et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2007)
PrDOS: prediction of disordered protein regions from amino acid sequence
Takashi Ishida et al.
NUCLEIC ACIDS RESEARCH (2007)
A comparative analysis of the fibulin protein family -: Biochemical characterization, binding interactions, and tissue localization
Naoyuki Kobayashi et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
Alternative splicing in concert with protein intrinsic disorder enables increased functional diversity in multicellular organisms
Pedro R. Romero et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
Length-dependent prediction of protein intrinsic disorder
Kang Peng et al.
BMC BIOINFORMATICS (2006)
Targeted disruption of fibulin-4 abolishes elastogenesis and causes perinatal lethality in mice
PJ McLaughlin et al.
MOLECULAR AND CELLULAR BIOLOGY (2006)
Fibulins 3 and 5 antagonize tumor angiogenesis in vivo
AR Albig et al.
CANCER RESEARCH (2006)
Defining the human macula transcriptome and 14 candidate retinal disease genes using EyeSAGE
Catherine Bowes Rickman et al.
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE (2006)
Aberrant accumulation of fibulin-3 in the endoplasmic reticulum leads to activation of the unfolded protein response and VEGF expression
CN Roybal et al.
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE (2005)
Coupled folding and binding with α-helix-forming molecular recognition elements
CJ Oldfield et al.
BIOCHEMISTRY (2005)
IUPred:: web server for the prediction of intrinsically unstructured regions of proteins based on estimated energy content
Z Dosztányi et al.
BIOINFORMATICS (2005)
The pairwise energy content estimated from amino acid composition discriminates between folded and intrinsically unstructured proteins
Z Dosztányi et al.
JOURNAL OF MOLECULAR BIOLOGY (2005)
Exploiting heterogeneous sequence properties improves prediction of protein disorder
Z Obradovic et al.
PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS (2005)
The importance of intrinsic disorder for protein phosphorylation
LM Iakoucheva et al.
NUCLEIC ACIDS RESEARCH (2004)
Degradation of misfolded proteins prevents ER-derived oxidative stress and cell death
CM Haynes et al.
MOLECULAR CELL (2004)
Tissue inhibitor of metalloproteinases-3 (TIMP-3) is a binding partner of epithelial growth factor-containing fibulin-like extracellular matrix protein 1 (EFEMP1) - Implications for macular degenerations
PA Klenotic et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Protein folding revisited. A polypeptide chain at the folding-misfolding-nonfolding cross-roads: which way to go?
VN Uversky
CELLULAR AND MOLECULAR LIFE SCIENCES (2003)
Cloning, expression and characterization of the murine Efemp1, a gene mutated in Doyne-Honeycomb retinal dystrophy
J Ehlermann et al.
GENE EXPRESSION PATTERNS (2003)
Intrinsically unstructured proteins
P Tompa
TRENDS IN BIOCHEMICAL SCIENCES (2002)
Aberrant accumulation of EFEMP1 underlies drusen formation in Malattia Leventinese and age-related macular degeneration
LHY Marmorstein et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)
Intrinsic disorder and protein function
AK Dunker et al.
BIOCHEMISTRY (2002)
Natively unfolded proteins: A point where biology waits for physics
VN Uversky
PROTEIN SCIENCE (2002)
Fibulin-5/DANCE is essential for elastogenesis in vivo
T Nakamura et al.
NATURE (2002)
What does it mean to be natively unfolded?
VN Uversky
EUROPEAN JOURNAL OF BIOCHEMISTRY (2002)
Intrinsically disordered protein
AK Dunker et al.
JOURNAL OF MOLECULAR GRAPHICS & MODELLING (2001)