Journal
CURRENT TOPICS IN MEDICINAL CHEMISTRY
Volume 16, Issue 30, Pages 3569-3581Publisher
BENTHAM SCIENCE PUBL LTD
DOI: 10.2174/1568026616666160526125352
Keywords
Anti-inflammatory agents; Azoles; Imidazoles; Oxadiazoles; Oxazoles; Pyrazoles; Thiazoles; Triazoles
Categories
Ask authors/readers for more resources
There has been considerable interest in azole-containing compounds as promising anti-inflammatory agents. Designed compounds with five-membered nitrogen-containing nuclei have demonstrated good anti-inflammatory activity, indicating their potential for the treatment of this highly irritating condition. Pyrazoles, have attracted much more attention than other azoles, however, reports on other azoles demonstrated that they were as effective as pyrazoles. This review describes the different classes of azoles designed as cyclooxygenase inhibitors and the effect of different structural modifications on their activity.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available