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Autophagy proteins regulate innate immune responses by inhibiting the release of mitochondrial DNA mediated by the NALP3 inflammasome
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Antiangiogenic therapy: impact on invasion, disease progression, and metastasis
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NATURE REVIEWS CLINICAL ONCOLOGY (2011)
Role of metal dyshomeostasis in Alzheimer's disease
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OPHTHALMOLOGY (2011)
Vascular Protection by Angiotensin Receptor Antagonism Involves Differential VEGF Expression in Both Hemispheres after Experimental Stroke
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PLOS ONE (2011)
VEGF is essential for hypoxia-inducible factor-mediated neovascularization but dispensable for endothelial sprouting
Sunday Oladipupo et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
Vascular pathology in the aged human brain
Lea Tenenholz Grinberg et al.
ACTA NEUROPATHOLOGICA (2010)
Critical role for lactate dehydrogenase A in aerobic glycolysis that sustains pulmonary microvascular endothelial cell proliferation
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AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY (2010)
Mechanisms of Cell Protection by Heme Oxygenase-1
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ANNUAL REVIEW OF PHARMACOLOGY AND TOXICOLOGY (2010)
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BLOOD (2010)
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A. R. Rezaie
CURRENT MEDICINAL CHEMISTRY (2010)
VEGF Receptor 2 Endocytic Trafficking Regulates Arterial Morphogenesis
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DEVELOPMENTAL CELL (2010)
Brain Endothelial Cells Produce Amyloid β from Amyloid Precursor Protein 770 and Preferentially Secrete the O-Glycosylated Form
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JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
BMP-9 induces proliferation of multiple types of endothelial cells in vitro and in vivo
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JOURNAL OF CELL SCIENCE (2010)
Nerve growth factor attenuates oxidant-induced β-amyloid neurotoxicity in sporadic Alzheimer's disease cybrids
Isaac G. Onyango et al.
JOURNAL OF NEUROCHEMISTRY (2010)
Pericytes regulate the blood-brain barrier
Annika Armulik et al.
NATURE (2010)
Pericytes Control Key Neurovascular Functions and Neuronal Phenotype in the Adult Brain and during Brain Aging
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NEURON (2010)
The Effects of Hemodynamic Force on Embryonic Development
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MICROCIRCULATION (2010)
Antiangiogenic Activity of 2-Deoxy-D-Glucose
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PLOS ONE (2010)
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CELL ADHESION & MIGRATION (2010)
Mitochondrial ABC proteins in health and disease
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BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS (2009)
Iron in arterial plaque: A modifiable risk factor for atherosclerosis
Jerome L. Sullivan
BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS (2009)
Iron behaving badly: inappropriate iron chelation as a major contributor to the aetiology of vascular and other progressive inflammatory and degenerative diseases
Douglas B. Kell
BMC MEDICAL GENOMICS (2009)
Changes in Human Endothelial Cell Energy Metabolic Capacities during in vitro Cultivation. The Role of Aerobic Glycolysis and Proliferation
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CELLULAR PHYSIOLOGY AND BIOCHEMISTRY (2009)
Arterial-Venous Specification During Development
Matthew R. Swift et al.
CIRCULATION RESEARCH (2009)
Amyloid beta, mitochondrial structural and functional dynamics in Alzheimer's disease
P. Hemachandra Reddy
EXPERIMENTAL NEUROLOGY (2009)
BCL-2: pro-or anti-oxidant?
Zhi Xiong Chen et al.
FRONTIERS IN BIOSCIENCE-LANDMARK (2009)
Attenuation of Angiotensin II-Induced Vascular Dysfunction and Hypertension by Overexpression of Thioredoxin 2
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HYPERTENSION (2009)
Vascular endothelial senescence: from mechanisms to pathophysiology
Jorge D. Erusalimsky
JOURNAL OF APPLIED PHYSIOLOGY (2009)
Distinct role of PLCβ3 in VEGF-mediated directional migration and vascular sprouting
Resham Bhattacharya et al.
JOURNAL OF CELL SCIENCE (2009)
MRI and Histological Analysis of Beta-Amyloid Plaques in Both Human Alzheimer's Disease and APP/PS1 Transgenic Mice
Mark D. Meadowcroft et al.
JOURNAL OF MAGNETIC RESONANCE IMAGING (2009)
Abcb10 physically interacts with mitoferrin-1 (Slc25a37) to enhance its stability and function in the erythroid mitochondria
Wen Chen et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
Hemodynamic shear stress and the endothelium in cardiovascular pathophysiology
Peter F. Davies
NATURE CLINICAL PRACTICE CARDIOVASCULAR MEDICINE (2009)
Neuropilin-1/GIPC1 Signaling Regulates alpha 5 beta 1 Integrin Traffic and Function in Endothelial Cells
Donatella Valdembri et al.
PLOS BIOLOGY (2009)
PARP-1 inhibition prevents oxidative and nitrosative stress-induced endothelial cell death via transactivation of the VEGF receptor 2
Marlene T. Mathews et al.
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2008)
Semaphorin-3B is an angiogenesis inhibitor that is inactivated by furin-like pro-protein convertases
Asya Varshavsky et al.
CANCER RESEARCH (2008)
Evidence for differential effects of hepcidin in macrophages and intestinal epithelial cells
T. Chaston et al.
GUT (2008)
Shc coordinates signals from intercellular junctions and integrins to regulate flow-induced inflammation
Yunhao Liu et al.
JOURNAL OF CELL BIOLOGY (2008)
Prohibitin-1 maintains the angiogenic capacity of endothelial cells by regulating mitochondrial function and senescence
Michael Schleicher et al.
JOURNAL OF CELL BIOLOGY (2008)
A potential pathogenetic role of iron in Alzheimer's disease
Laura Silvestri et al.
JOURNAL OF CELLULAR AND MOLECULAR MEDICINE (2008)
The Angiopoietin-2 Gene of Endothelial Cells is Up-Regulated in Hypoxia by a HIF Binding Site Located in Its First Intron and by the Central Factors GATA-2 and Ets-1
Marie-Pierre Simon et al.
JOURNAL OF CELLULAR PHYSIOLOGY (2008)
Neuropilin-1 is a receptor for transforming growth factor β-1, activates its latent form, and promotes regulatory T cell activity
Yelena Glinka et al.
JOURNAL OF LEUKOCYTE BIOLOGY (2008)
Markers of endothelial dysfunction in older subjects with late onset Alzheimer's disease or vascular dementia
G. Zuliani et al.
JOURNAL OF THE NEUROLOGICAL SCIENCES (2008)
Vascular endothelial growth factor in eye disease
J. S. Penn et al.
PROGRESS IN RETINAL AND EYE RESEARCH (2008)
Role of nitric oxide and prostacyclin as vasoactive hormones released by the endothelium
Jane A. Mitchell et al.
EXPERIMENTAL PHYSIOLOGY (2008)
Oxidative stress and cerebrovascular dysfunction in mouse models of Alzheimer's disease
E. Hamel et al.
EXPERIMENTAL PHYSIOLOGY (2008)
Modulation of Ca2+ transients in cultured endothelial cells in response to fluid flow through αv integrin
Takuro Miyazaki et al.
LIFE SCIENCES (2007)
Molecular mechanisms of plaque instability
Prediman K. Shah
CURRENT OPINION IN LIPIDOLOGY (2007)
Vascular remodeling of the mouse yolk sac requires hemodynamic force
Jennifer L. Lucitti et al.
DEVELOPMENT (2007)
Non-transferrin-bound iron is associated with plasma level of soluble intercellular adhesion molecule-1 but not with in vivo low-density lipoprotein oxidation
L. J. H. van Tits et al.
ATHEROSCLEROSIS (2007)
Cytochrome c oxidase deficiency in neurons decreases both oxidative stress and amyloid formation in a mouse model of Alzheimer's disease
Hirokazu Fukui et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
Forum original research communication
Thomas K. Hunt et al.
ANTIOXIDANTS & REDOX SIGNALING (2007)
Mitochondrial dysfunction accounts for the stochastic heterogeneity in telomere-dependent senescence
Joao F. Passos et al.
PLOS BIOLOGY (2007)
Endothelial mitochondria - Contributing to vascular function and disease
Sean M. Davidson et al.
CIRCULATION RESEARCH (2007)
Reduction of iron stores and cardiovascular outcomes in patients with peripheral arterial disease - A randomized controlled trial
Leo R. Zacharski et al.
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2007)
A paxillin tyrosine phosphorylation switch regulates the assembly and form of cell-matrix adhesions
Ronen Zaidel-Bar et al.
JOURNAL OF CELL SCIENCE (2007)
Blocking neuropilin-1 function has an additive effect with anti-VEGF to inhibit tumor growth
Qi Pan et al.
CANCER CELL (2007)
Matrix-specific suppression of integrin activation in shear stress signaling
A. W. Orr et al.
MOLECULAR BIOLOGY OF THE CELL (2006)
Identification of a mammalian mitochondrial porphyrin transporter
Partha C. Krishnamurthy et al.
NATURE (2006)
Inhibition of endothelial cell proliferation and angiogenesis by orlistat, a fatty acid synthase inhibitor
Cecille D. Browne et al.
FASEB JOURNAL (2006)
Assessing iron status: Beyond serum ferritin and transferrin saturation
Jay B. Wish
CLINICAL JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2006)
Amyloid β-peptide1-42 alters tight junction protein distribution and expression in brain microvessel endothelial cells
Sonia Marco et al.
NEUROSCIENCE LETTERS (2006)
Hereditary hemochromatosis
Antonello Pietrangelo
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2006)
Mitochondria as signaling organelles in the vascular endothelium
M Quintero et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
An update on visfatin/pre-B cell colony-enhancing factor, an ubiquitously expressed, illusive cytokine that is regulated in obesity
JM Stephens et al.
CURRENT OPINION IN LIPIDOLOGY (2006)
Molecular mechanisms of the vascular responses to haemodynamic forces
S Lehoux et al.
JOURNAL OF INTERNAL MEDICINE (2006)
Endothelial activation and induction of monocyte adhesion by nontransferrin-bound iron present in human sera
Apriliana E. R. Kartikasari et al.
FASEB JOURNAL (2006)
Endothelial extracellular matrix - Biosynthesis, remodeling, and functions during vascular morphogenesis and neovessel stabilization
GE Davis et al.
CIRCULATION RESEARCH (2005)
Plasma visfatin concentrations and fat depot-specific mRNA expression in humans
J Berndt et al.
DIABETES (2005)
Pathophysiological consequences of VEGF-induced vascular permeability
SM Weis et al.
NATURE (2005)
A mechanosensory complex that mediates the endothelial cell response to fluid shear stress
E Tzima et al.
NATURE (2005)
VEGF protects brain against focal ischemia without increasing blood-brain permeability when administered intracerebroventricularly
D Kaya et al.
JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM (2005)
Up-regulation of gene expression by hypoxia is mediated predominantly by hypoxia-inducible factor 1 (HIF-1)
AE Greijer et al.
JOURNAL OF PATHOLOGY (2005)
Neuropilin-1 regulates vascular endothelial growth factor-mediated endothelial permeability
PM Becker et al.
CIRCULATION RESEARCH (2005)
The pathobiology of diabetic complications - A unifying mechanism
M Brownlee
DIABETES (2005)
Neuropilin-1 regulates attachment in human endothelial cells independently of vascular endothelial growth factor receptor-2
M Murga et al.
BLOOD (2005)
Mechanism of mitochondrial uncouplers, inhibitors, and toxins: Focus on electron transfer, free radicals, and structure-activity relationships
P Kovacic et al.
CURRENT MEDICINAL CHEMISTRY (2005)
Nox enzymes and the biology of reactive oxygen
JD Lambeth
NATURE REVIEWS IMMUNOLOGY (2004)
Vascular endothelial growth factor activates PI3K/Akt/forkhead signaling in endothelial cells
R Abid et al.
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2004)
Phosphorylation of tyrosine 1214 on VEGFR2 is required for VEGF-induced activation of Cdc42 upstream of SAPK2/p38
L Lamalice et al.
ONCOGENE (2004)
Elevated fluid shear stress enhances postocclusive collateral artery growth and gene expression in the pig hind limb
F Pipp et al.
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2004)
Reactive oxygen species in hypertension -: An update
B Lassègue et al.
AMERICAN JOURNAL OF HYPERTENSION (2004)
Multiprotein complex containing succinate dehydrogenase confers mitochondrial ATP-sensitive K+ channel activity
H Ardehali et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
Hepcidin regulates cellular iron efflux by binding to ferroportin and inducing its internalization
E Nemeth et al.
SCIENCE (2004)
Intracellular labile iron modulates adhesion of human monocytes to human endothelial cells
AER Kartikasari et al.
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2004)
Complex III releases superoxide to both sides of the inner mitochondrial membrane
FL Muller et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Periodic Delta-like 4 expression in developing retinal arteries
S Claxton et al.
GENE EXPRESSION PATTERNS (2004)
Direct detection and quantification of transition metal ions in human atherosclerotic plaques: Evidence for the presence of elevated levels of iron and copper
N Stadler et al.
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2004)
Molecular mechanisms of replicative senescence in endothelial cells
KE Foreman et al.
EXPERIMENTAL GERONTOLOGY (2003)
Localized Cdc42 activation, detected using a novel assay, mediates microtubule organizing center positioning in endothelial cells in response to fluid shear stress
E Tzima et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Neuropilin-1 conveys semaphorin and VEGF signaling during neural and cardiovascular development
CH Gu et al.
DEVELOPMENTAL CELL (2003)
VEGF guides angiogenic sprouting utilizing endothelial tip cell filopodia
H Gerhardt et al.
JOURNAL OF CELL BIOLOGY (2003)
VEGF-induced neuroprotection, neurogenesis, and angiogenesis after focal cerebral ischemia
YJ Sun et al.
JOURNAL OF CLINICAL INVESTIGATION (2003)
Regulation of angiogenesis by hypoxia: role of the HIF system
CW Pugh et al.
NATURE MEDICINE (2003)
Molecular regulation of vessel maturation
RK Jain
NATURE MEDICINE (2003)
Elevated beta-secretase expression and enzymatic activity detected in sporadic Alzheimer disease
LB Yang et al.
NATURE MEDICINE (2003)
Association between increased iron stores and impaired endothelial function in patients with hereditary hemochromatosis
H Gaenzer et al.
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2002)
Activation of Rac1 by shear stress in endothelial cells mediates both cytoskeletal reorganization and effects on gene expression
E Tzima et al.
EMBO JOURNAL (2002)
An iron-responsive element type II in the 5′-untranslated region of the Alzheimer's amyloid precursor protein transcript
JT Rogers et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Spatially restricted patterning cues provided by heparin-binding VEGF-A control blood vessel branching morphogenesis
C Ruhrberg et al.
GENES & DEVELOPMENT (2002)
β-secretase protein and activity are increased in the neocortex in Alzheimer disease
H Fukumoto et al.
ARCHIVES OF NEUROLOGY (2002)
Mitochondrial integrity and function in atherogenesis
SW Ballinger et al.
CIRCULATION (2002)
Neuropilin-1 binds vascular endothelial growth factor 165, placenta growth factor-2, and heparin via its b1b2 domain
R Mamluk et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Increased expression of the amyloid precursor β-secretase in Alzheimer's disease
RMD Holsinger et al.
ANNALS OF NEUROLOGY (2002)
Characterization of neuropilin-1 structural features that confer binding to semaphorin 3A and vascular endothelial growth factor 165
CH Gu et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Endothelial cell senescence in human atherosclerosis - Role of telomere in endothelial dysfunction
T Minamino et al.
CIRCULATION (2002)
Correlation of VEGF and angiopoietin expression with disruption of blood-brain barrier and angiogenesis after focal cerebral ischemia
ZG Zhang et al.
JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM (2002)
Role of mitochondrial oxidant generation in endothelial cell responses to hypoxia
DP Pearlstein et al.
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2002)
Inflammation and atherosclerosis
P Libby et al.
CIRCULATION (2002)
Hypoxia-inducible factor-1-mediated expression of the 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase-3 (PFKFB3) gene -: Its possible role in the Warburg effect
A Minchenko et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Reactive oxygen species as downstream mediators of angiogenic signaling by vascular endothelial growth factor receptor-2/KDR
R Colavitti et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Angiogenic and astroglial responses to vascular endothelial growth factor administration in adult rat brain
JM Krum et al.
NEUROSCIENCE (2002)
Abnormalities in pericytes on blood vessels and endothelial sprouts in tumors
S Morikawa et al.
AMERICAN JOURNAL OF PATHOLOGY (2002)
Activation of integrins in endothelial cells by fluid shear stress mediates Rho-dependent cytoskeletal alignment
E Tzima et al.
EMBO JOURNAL (2001)
The human ATP-binding cassette (ABC) transporter superfamily
M Dean et al.
GENOME RESEARCH (2001)
Amyloid β peptide-induced cerebral endothelial cell death involves mitochondrial dysfunction and caspase activation
J Xu et al.
JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM (2001)
Role of vascular endothelial growth factor in regulation of physiological angiogenesis
N Ferrara
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY (2001)
Metabolic regulation of brain Aβ by neprilysin
N Iwata et al.
SCIENCE (2001)
Mitochondrial abnormalities in Alzheimer's disease
K Hirai et al.
JOURNAL OF NEUROSCIENCE (2001)
Cooperation and competition in the evolution of ATP-producing pathways
T Pfeiffer et al.
SCIENCE (2001)
FGF and VEGF function in angiogenesis: signalling pathways, biological responses and therapeutic inhibition
MJ Cross et al.
TRENDS IN PHARMACOLOGICAL SCIENCES (2001)
Spontaneous and flow-induced Ca2+ transients in retracted regions in endothelial cells
T Miyazaki et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2001)
Differential expression of thymosin β-10 by early passage and senescent vascular endothelium is modulated by VPF/VEGF:: evidence for senescent endothelial cells in vivo at sites of atherosclerosis
E Vasile et al.
FASEB JOURNAL (2001)
ATP modulates subunit-subunit interactions in an ATP-binding cassette transporter (MalFGK2) determined by site-directed chemical cross-linking
S Hunke et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
Identification of the major Aβ1-42-degrading catabolic pathway in brain parenchyma:: Suppression leads to biochemical and pathological deposition
N Iwata et al.
NATURE MEDICINE (2000)