Related references
Note: Only part of the references are listed.NOX4 Inhibition Potentiates Immunotherapy by Overcoming Cancer-Associated Fibroblast-Mediated CD8 T-cell Exclusion from Tumors
Kirsty Ford et al.
CANCER RESEARCH (2020)
Blockade of Stromal Gas6 Alters Cancer Cell Plasticity, Activates NK Cells, and Inhibits Pancreatic Cancer Metastasis
Lucy Ireland et al.
FRONTIERS IN IMMUNOLOGY (2020)
Stromal cell diversity associated with immune evasion in human triple-negative breast cancer
Sunny Z. Wu et al.
EMBO JOURNAL (2020)
A framework for advancing our understanding of cancer-associated fibroblasts
Erik Sahai et al.
NATURE REVIEWS CANCER (2020)
A guide to cancer immunotherapy: from T cell basic science to clinical practice
Alex D. Waldman et al.
NATURE REVIEWS IMMUNOLOGY (2020)
Extracellular Matrix in the Tumor Microenvironment and Its Impact on Cancer Therapy
Erik Henke et al.
FRONTIERS IN MOLECULAR BIOSCIENCES (2020)
CD8+ T-cell exhaustion in cancer: mechanisms and new area for cancer immunotherapy
Qi-Feng He et al.
BRIEFINGS IN FUNCTIONAL GENOMICS (2019)
Cancer-associated fibroblasts: Secretions, interactions, and therapy
Bagher Farhood et al.
JOURNAL OF CELLULAR BIOCHEMISTRY (2019)
Neoepitopes-based vaccines: challenges and perspectives
Vincent Alcazer et al.
EUROPEAN JOURNAL OF CANCER (2019)
Cancer-associated fibroblasts promote PD-L1 expression in mice cancer cells via secreting CXCL5
Ziqian Li et al.
INTERNATIONAL JOURNAL OF CANCER (2019)
Collagen density regulates the activity of tumor-infiltrating T cells
Dorota E. Kuczek et al.
JOURNAL FOR IMMUNOTHERAPY OF CANCER (2019)
The extracellular matrix in tumor progression and metastasis
Johannes A. Eble et al.
CLINICAL & EXPERIMENTAL METASTASIS (2019)
Fibroblasts as Modulators of Local and Systemic Cancer Metabolism
Hannah Sanford-Crane et al.
CANCERS (2019)
Cross-Species Single-Cell Analysis of Pancreatic Ductal Adenocarcinoma Reveals Antigen-Presenting Cancer-Associated Fibroblasts
Ela Elyada et al.
CANCER DISCOVERY (2019)
Human Pancreatic Carcinoma-Associated Fibroblasts Promote Expression of Co-inhibitory Markers on CD4+ and CD8+ T-Cells
Laia Gorchs et al.
FRONTIERS IN IMMUNOLOGY (2019)
Deoxycytidine Release from Pancreatic Stellate Cells Promotes Gemcitabine Resistance
Simona Dalin et al.
CANCER RESEARCH (2019)
Cancer-associated fibroblasts: an emerging target of anti-cancer immunotherapy
Tongyan Liu et al.
JOURNAL OF HEMATOLOGY & ONCOLOGY (2019)
Proteomic analyses of ECM during pancreatic ductal adenocarcinoma progression reveal different contributions by tumor and stromal cells
Chenxi Tian et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2019)
The Dark Side of Fibroblasts: Cancer-Associated Fibroblasts as Mediators of Immunosuppression in the Tumor Microenvironment
Lea Monteran et al.
FRONTIERS IN IMMUNOLOGY (2019)
Role of hypoxia in cancer therapy by regulating the tumor microenvironment
Xinming Jing et al.
MOLECULAR CANCER (2019)
Tumor-Stroma Mechanics Coordinate Amino Acid Availability to Sustain Tumor Growth and Malignancy
Thomas Bertero et al.
CELL METABOLISM (2019)
Stromal protein βig-h3 reprogrammes tumour microenvironment in pancreatic cancer
Delphine Goehrig et al.
GUT (2019)
Lactate modulates CD4+ T-cell polarization and induces an immunosuppressive environment, which sustains prostate carcinoma progression via TLR8/miR21 axis
G. Comito et al.
ONCOGENE (2019)
Targeting the Myofibroblastic Cancer-Associated Fibroblast Phenotype Through Inhibition of NOX4
Christopher J. Hanley et al.
JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE (2018)
CD22-targeted CAR T cells induce remission in B-ALL that is naive or resistant to CD19-targeted CAR immunotherapy
Terry J. Fry et al.
NATURE MEDICINE (2018)
Targeting the Myofibroblastic Cancer-Associated Fibroblast Phenotype Through Inhibition of NOX4
Christopher J. Hanley et al.
JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE (2018)
Potent anti-leukemia activities of humanized CD19-targeted Chimeric antigen receptor T (CAR-T) cells in patients with relapsed/refractory acute lymphoblastic leukemia
Jiang Cao et al.
AMERICAN JOURNAL OF HEMATOLOGY (2018)
Fibroblast Heterogeneity and Immunosuppressive Environment in Human Breast Cancer
Ana Costa et al.
CANCER CELL (2018)
Macrophage-Derived Granulin Drives Resistance to Immune Checkpoint Inhibition in Metastatic Pancreatic Cancer
Valeria Quaranta et al.
CANCER RESEARCH (2018)
Combined Blockade of IL6 and PD-1/PD-L1 Signaling Abrogates Mutual Regulation of Their Immunosuppressive Effects in the Tumor Microenvironment
Hirotake Tsukamoto et al.
CANCER RESEARCH (2018)
Prognostic value of intra-tumoral CD8+/FoxP3+ lymphocyte ratio in patients with resected colorectal cancer liver metastasis
Kostandinos Sideras et al.
JOURNAL OF SURGICAL ONCOLOGY (2018)
Use of the tumor-infiltrating CD8 to FOXP3 lymphocyte ratio in predicting treatment responses to combination therapy with pertuzumab, trastuzumab, and docetaxel for advanced HER2-positive breast cancer
Koji Takada et al.
JOURNAL OF TRANSLATIONAL MEDICINE (2018)
TGFβ drives immune evasion in genetically reconstituted colon cancer metastasis
Daniele V. F. Tauriello et al.
NATURE (2018)
Blockade of insulin-like growth factors increases efficacy of paclitaxel in metastatic breast cancer
Lucy Ireland et al.
ONCOGENE (2018)
Cancer-associated fibroblasts induce PDL1+neutrophils through the IL6-STAT3 pathway that foster immune suppression in hepatocellular carcinoma
Yusheng Cheng et al.
CELL DEATH & DISEASE (2018)
Cancer-associated fibroblasts induce antigen-specific deletion of CD8+ T Cells to protect tumour cells
Matthew A. Lakins et al.
NATURE COMMUNICATIONS (2018)
Targeting stromal remodeling and cancer stem cell plasticity overcomes chemoresistance in triple negative breast cancer
Aurelie S. Cazet et al.
NATURE COMMUNICATIONS (2018)
Metabolic Reprogramming of Cancer Associated Fibroblasts: The Slavery of Stromal Fibroblasts
Angelica Avagliano et al.
BIOMED RESEARCH INTERNATIONAL (2018)
Blockade of MIF-CD74 Signalling on Macrophages and Dendritic Cells Restores the Antitumour Immune Response Against Metastatic Melanoma
Carlos R. Figueiredo et al.
FRONTIERS IN IMMUNOLOGY (2018)
Alteration of the Antitumor immune Response by Cancer-Associated Fibroblasts
Linda Ziani et al.
FRONTIERS IN IMMUNOLOGY (2018)
Targeting adenosine for cancer immunotherapy
Robert D. Leone et al.
JOURNAL FOR IMMUNOTHERAPY OF CANCER (2018)
TGFβ attenuates tumour response to PD-L1 blockade by contributing to exclusion of T cells
Sanjeev Mariathasan et al.
NATURE (2018)
Signatures of T cell dysfunction and exclusion predict cancer immunotherapy response
Peng Jiang et al.
NATURE MEDICINE (2018)
Targeted hypoxia reduction restores T cell infiltration and sensitizes prostate cancer to immunotherapy
Priyamvada Jayaprakash et al.
JOURNAL OF CLINICAL INVESTIGATION (2018)
Bone marrow-derived fibroblasts are a functionally distinct stromal cell population in breast cancer
Yael Raz et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2018)
PD-L1 on tumor cells is sufficient for immune evasion in immunogenic tumors and inhibits CD8 T cell cytotoxicity
Vikram R. Juneja et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2017)
Spatial computation of intratumoral T cells correlates with survival of patients with pancreatic cancer
Julienne L. Carstens et al.
NATURE COMMUNICATIONS (2017)
Increasing Tumor-Infiltrating T Cells through Inhibition of CXCL12 with NOX-A12 Synergizes with PD-1 Blockade
Dirk Zboralski et al.
CANCER IMMUNOLOGY RESEARCH (2017)
Prognostic value of programmed cell death protein 1 expression on CD8+T lymphocytes in pancreatic cancer
Tao Shen et al.
SCIENTIFIC REPORTS (2017)
Fibroblast activation protein augments progression and metastasis of pancreatic ductal adenocarcinoma
Albert Lo et al.
JCI INSIGHT (2017)
Tumor antigen-specific CD8+ T cells are negatively regulated by PD-1 and Tim-3 in human gastric cancer
Xu Lu et al.
CELLULAR IMMUNOLOGY (2017)
Chemoresistance in Pancreatic Cancer Is Driven by Stroma-Derived Insulin-Like Growth Factors
Lucy Ireland et al.
CANCER RESEARCH (2016)
Carcinoma-associated fibroblasts: orchestrating the composition of malignancy
Philippe Gascard et al.
GENES & DEVELOPMENT (2016)
Co-stimulatory and Co-inhibitory Pathways in Autoimmunity
Qianxia Zhang et al.
IMMUNITY (2016)
Chemoattractant Receptors BLT1 and CXCR3 Regulate Antitumor Immunity by Facilitating CD8+ T Cell Migration into Tumors
Zinal S. Chheda et al.
JOURNAL OF IMMUNOLOGY (2016)
Mesenchymal stromal cells derived from cervical cancer produce high amounts of adenosine to suppress cytotoxic T lymphocyte functions
Maria de Lourdes Mora-Garcia et al.
JOURNAL OF TRANSLATIONAL MEDICINE (2016)
Macrophage-secreted granulin supports pancreatic cancer metastasis by inducing liver fibrosis
Sebastian R. Nielsen et al.
NATURE CELL BIOLOGY (2016)
Targeting focal adhesion kinase renders pancreatic cancers responsive to checkpoint immunotherapy
Hong Jiang et al.
NATURE MEDICINE (2016)
Prognostic value, localization and correlation of PD-1/PD-L1, CD8 and FOXP3 with the desmoplastic stroma in pancreatic ductal adenocarcinoma
Angela Diana et al.
ONCOTARGET (2016)
Hepatic carcinoma-associated fibroblasts induce IDO-producing regulatory dendritic cells through IL-6-mediated STAT3 activation
J-t Cheng et al.
ONCOGENESIS (2016)
The biology and function of fibroblasts in cancer
Raghu Kalluri
NATURE REVIEWS CANCER (2016)
βig-h3 Represses T-Cell Activation in Type 1 Diabetes
Maeva Patry et al.
DIABETES (2015)
Non-redundant requirement for CXCR3 signalling during tumoricidal T-cell trafficking across tumour vascular checkpoints
M. E. Mikucki et al.
NATURE COMMUNICATIONS (2015)
Lactate Regulates Metabolic and Proinflammatory Circuits in Control of T Cell Migration and Effector Functions
Robert Haas et al.
PLOS BIOLOGY (2015)
Real-time imaging of resident T cells in human lung and ovarian carcinomas reveals how different tumor microenvironments control T lymphocyte migration
Houcine Bougherara et al.
FRONTIERS IN IMMUNOLOGY (2015)
Cancer-Associated Fibroblasts: Their Characteristics and Their Roles in Tumor Growth
Kazuyoshi Shiga et al.
CANCERS (2015)
Histologic Categorization of Desmoplastic Reaction: Its Relevance to the Colorectal Cancer Microenvironment and Prognosis
Hideki Ueno et al.
ANNALS OF SURGICAL ONCOLOGY (2015)
Immunological hallmarks of stromal cells in the tumour microenvironment
Shannon J. Turley et al.
NATURE REVIEWS IMMUNOLOGY (2015)
Depletion of Carcinoma-Associated Fibroblasts and Fibrosis Induces Immunosuppression and Accelerates Pancreas Cancer with Reduced Survival
Berna C. Oezdemir et al.
CANCER CELL (2014)
Stromal Elements Act to Restrain, Rather Than Support, Pancreatic Ductal Adenocarcinoma
Andrew D. Rhim et al.
CANCER CELL (2014)
Prevailing Role of Contact Guidance in Intrastromal T-cell Trapping in Human Pancreatic Cancer
Natalie Hartmann et al.
CLINICAL CANCER RESEARCH (2014)
PD-1 blockade induces responses by inhibiting adaptive immune resistance
Paul C. Tumeh et al.
NATURE (2014)
Activated Pancreatic Stellate Cells Sequester CD8+ T Cells to Reduce Their Infiltration of the Juxtatumoral Compartment of Pancreatic Ductal Adenocarcinoma
Abasi Ene-Obong et al.
GASTROENTEROLOGY (2013)
Oncology Meets Immunology: The Cancer-Immunity Cycle
Daniel S. Chen et al.
IMMUNITY (2013)
Depletion of stromal cells expressing fibroblast activation protein-α from skeletal muscle and bone marrow results in cachexia and anemia
Edward W. Roberts et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2013)
Arginase II Expressed in Cancer-Associated Fibroblasts Indicates Tissue Hypoxia and Predicts Poor Outcome in Patients with Pancreatic Cancer
Yoshinori Ino et al.
PLOS ONE (2013)
Targeting CXCL12 from FAP-expressing carcinomaassociated fibroblasts synergizes with anti-PD-L1 immunotherapy in pancreatic cancer
Christine Feig et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
Ways to enhance lymphocyte trafficking into tumors and fitness of tumor infiltrating lymphocytes
Matteo Bellone et al.
FRONTIERS IN ONCOLOGY (2013)
HIF-1α/GPER signaling mediates the expression of VEGF induced by hypoxia in breast cancer associated fibroblasts (CAFs)
Ernestina Marianna De Francesco et al.
BREAST CANCER RESEARCH (2013)
Modulation of Microenvironment Acidity Reverses Anergy in Human and Murine Tumor-Infiltrating T Lymphocytes
Arianna Calcinotto et al.
CANCER RESEARCH (2012)
Oncogenic BRAF(V600E) Promotes Stromal Cell-Mediated Immunosuppression Via Induction of Interleukin-1 in Melanoma
Jahan S. Khalili et al.
CLINICAL CANCER RESEARCH (2012)
The Prognostic Value of FoxP3+ Tumor-Infiltrating Lymphocytes in Cancer: A Critical Review of the Literature
Ronald J. deLeeuw et al.
CLINICAL CANCER RESEARCH (2012)
Tumor lactic acidosis suppresses CTL function by inhibition of p38 and JNK/c-Jun activation
Anna N. Mendler et al.
INTERNATIONAL JOURNAL OF CANCER (2012)
Matrix architecture defines the preferential localization and migration of T cells into the stroma of human lung tumors
Helene Salmon et al.
JOURNAL OF CLINICAL INVESTIGATION (2012)
Bone Marrow-Derived Myofibroblasts Contribute to the Mesenchymal Stem Cell Niche and Promote Tumor Growth
Michael Quante et al.
CANCER CELL (2011)
Chemotherapy Induces Intratumoral Expression of Chemokines in Cutaneous Melanoma, Favoring T-cell Infiltration and Tumor Control
Michelle Hong et al.
CANCER RESEARCH (2011)
Exhaustion of tumor-specific CD8+ T cells in metastases from melanoma patients
Lukas Baitsch et al.
JOURNAL OF CLINICAL INVESTIGATION (2011)
Reciprocal Functional Modulation of the Activation of T Lymphocytes and Fibroblasts Derived from Human Solid Tumors
Jennifer L. Barnas et al.
JOURNAL OF IMMUNOLOGY (2010)
Tumor-infiltrating NY-ESO-1-specific CD8+ T cells are negatively regulated by LAG-3 and PD-1 in human ovarian cancer
Junko Matsuzaki et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
Suppression of Antitumor Immunity by Stromal Cells Expressing Fibroblast Activation Protein-α
Matthew Kraman et al.
SCIENCE (2010)
Arginase: an emerging key player in the mammalian immune system
Markus Munder
BRITISH JOURNAL OF PHARMACOLOGY (2009)
Chemokine Expression in Melanoma Metastases Associated with CD8+ T-Cell Recruitment
Helena Harlin et al.
CANCER RESEARCH (2009)
The reverse Warburg effect Aerobic glycolysis in cancer associated fibroblasts and the tumor stroma
Stephanos Pavlides et al.
CELL CYCLE (2009)
The tumor microenvironment and its role in promoting tumor growth
T. L. Whiteside
ONCOGENE (2008)
Inhibitory effect of tumor cell-derived lactic acid on human T cells
Karin Fischer et al.
BLOOD (2007)
Share Paper
