Related references
Note: Only part of the references are listed.The intricate relationship between diabetes, obesity and pancreatic cancer
Silvano Paternoster et al.
BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER (2020)
AdipoRon Affects Cell Cycle Progression and Inhibits Proliferation in Human Osteosarcoma Cells
Luigi Sapio et al.
JOURNAL OF ONCOLOGY (2020)
The impact of metformin and aspirin on T -cell mediated inflammation: A systematic review of in vitro and in vivo findings
Tawanda Maurice Nyambuya et al.
LIFE SCIENCES (2020)
Hypertriglyceridemia-induced acute pancreatitis: A prospective, multicenter, international cohort analysis of 716 acute pancreatitis cases
Dora Mosztbacher et al.
PANCREATOLOGY (2020)
How the ageing microenvironment influences tumour progression
Mitchell Fane et al.
NATURE REVIEWS CANCER (2020)
High Glucose Triggers Nucleotide Imbalance through O-GlcNAcylation of Key Enzymes and Induces KRAS Mutation in Pancreatic Cells
Chun-Mei Hu et al.
CELL METABOLISM (2019)
Age-related morphological changes in the pancreas and their association with pancreatic carcinogenesis
Yoko Matsuda
PATHOLOGY INTERNATIONAL (2019)
Endogenous Hyperinsulinemia Contributes to Pancreatic Cancer Development
Anni M. Y. Zhang et al.
CELL METABOLISM (2019)
Does obesity cause type 2 diabetes mellitus (T2DM)? Or is it the opposite?
John I. Malone et al.
PEDIATRIC DIABETES (2019)
Aspirin use and pancreatic cancer risk A systematic review of observational studies
Jinjin Sun et al.
MEDICINE (2019)
Adiponectin Suppresses Human Pancreatic Cancer Growth through Attenuating the β-Catenin Signaling Pathway
Jinghui Jiang et al.
INTERNATIONAL JOURNAL OF BIOLOGICAL SCIENCES (2019)
Combinatorial Treatment with mTOR Inhibitors and Streptozotocin Leads to Synergistic In Vitro and In Vivo Antitumor Effects in Insulinoma Cells
Julien Bollard et al.
MOLECULAR CANCER THERAPEUTICS (2018)
Cancer Statistics, 2018
Rebecca L. Siegel et al.
CA-A CANCER JOURNAL FOR CLINICIANS (2018)
Diabetes as risk factor for pancreatic cancer: Hyperglycemia promotes epithelial-mesenchymal-transition and stem cell properties in pancreatic ductal epithelial cells
Sascha Rahn et al.
CANCER LETTERS (2018)
The IGF pathway is activated in insulinomas but downregulated in metastatic disease
Mieke E. R. Henfling et al.
ENDOCRINE-RELATED CANCER (2018)
Mutations in Mitochondrial DNA From Pancreatic Ductal Adenocarcinomas Associate With Survival Times of Patients and Accumulate as Tumors Progress
Julia F. Hopkins et al.
GASTROENTEROLOGY (2018)
Regular Use of Aspirin or Non-Aspirin Nonsteroidal Anti-Inflammatory Drugs Is Not Associated With Risk of Incident Pancreatic Cancer in Two Large Cohort Studies
Natalia Khalaf et al.
GASTROENTEROLOGY (2018)
Acute Pancreatitis and Pancreatic Cancer Risk: A Nationwide Matched-Cohort Study in Denmark
Jakob Kirkegard et al.
GASTROENTEROLOGY (2018)
Metformin as first-line treatment for type 2 diabetes
Suetonia C. Palmer et al.
LANCET (2018)
MAFA missense mutation causes familial insulinomatosis and diabetes mellitus
Donato Iacovazzo et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2018)
Metformin Decreases the Incidence of Pancreatic Ductal Adenocarcinoma Promoted by Diet-induced Obesity in the Conditional KrasG12D Mouse Model
Hui-Hua Chang et al.
SCIENTIFIC REPORTS (2018)
Antidiabetic adiponectin receptor agonist AdipoRon suppresses tumour growth of pancreatic cancer by inducing RIPK1/ERK-dependent necroptosis
Miho Akimoto et al.
CELL DEATH & DISEASE (2018)
Pancreatic Cancer and Obesity: Molecular Mechanisms of Cell Transformation and Chemoresistance
Priscilla Cascetta et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2018)
mTORC1 Overactivation as a Key Aging Factor in the Progression to Type 2 Diabetes Mellitus
Carlos Guillen et al.
FRONTIERS IN ENDOCRINOLOGY (2018)
Mitochondrial Protein UCP2 Controls Pancreas Development
Benjamin Broche et al.
DIABETES (2018)
The IGF system in patients with type 2 diabetes: associations with markers of cardiovascular target organ damage
Rikke Hjortebjerg et al.
EUROPEAN JOURNAL OF ENDOCRINOLOGY (2017)
Diabetes, plasma glucose and incidence of pancreatic cancer: A prospective study of 0.5 million Chinese adults and a meta-analysis of 22 cohort studies
Yuanjie Pang et al.
INTERNATIONAL JOURNAL OF CANCER (2017)
The Prevalence and Clinicopathological Characteristics of High-Grade Pancreatic Intraepithelial Neoplasia Autopsy Study Evaluating the Entire Pancreatic Parenchyma
Yoko Matsuda et al.
PANCREAS (2017)
The Biology of Aging and Cancer: A Brief Overview of Shared and Divergent Molecular Hallmarks
Jan R. Aunan et al.
AGING AND DISEASE (2017)
Aging, Metabolism, and Cancer Development: from Peto's Paradox to the Warburg Effect
Tia R. Tidwell et al.
AGING AND DISEASE (2017)
Incidence of pancreatic cancer is dramatically increased by a high fat, high calorie diet in KrasG12D mice
Hui-Hua Chang et al.
PLOS ONE (2017)
The effect of metformin on survival of patients with pancreatic cancer: a meta-analysis
Xiaogang Li et al.
SCIENTIFIC REPORTS (2017)
Lipocalin-2 Promotes Pancreatic Ductal Adenocarcinoma by Regulating Inflammation in the Tumor Microenvironment
Sobeyda B. Gomez-Chou et al.
CANCER RESEARCH (2017)
Diabetes, Pancreatogenic Diabetes, and Pancreatic Cancer
Dana K. Andersen et al.
DIABETES (2017)
mTOR Signaling in Growth, Metabolism, and Disease
Robert A. Saxton et al.
CELL (2017)
Insulin-Like Growth Factor 1 and Insulin-Like Growth Factor-Binding Protein 3 in Relation to the Risk of Type 2 Diabetes Mellitus: Results From the EPIC-Potsdam Study
Dagmar Drogan et al.
AMERICAN JOURNAL OF EPIDEMIOLOGY (2016)
The Mechanistic Target of Rapamycin: The Grand ConducTOR of Metabolism and Aging
Brian K. Kennedy et al.
CELL METABOLISM (2016)
Effects of ageing and senescence on pancreatic β-cell function
A. Helman et al.
DIABETES OBESITY & METABOLISM (2016)
Differential expression of cell-cycle regulators in human beta-cells derived from insulinoma tissue
Sandra Ueberberg et al.
METABOLISM-CLINICAL AND EXPERIMENTAL (2016)
Obesity-Induced Inflammation and Desmoplasia Promote Pancreatic Cancer Progression and Resistance to Chemotherapy
Joao Incio et al.
CANCER DISCOVERY (2016)
Targeting mTOR in Pancreatic Ductal Adenocarcinoma
Sentia Iriana et al.
FRONTIERS IN ONCOLOGY (2016)
Obesity and Fatty Pancreatic Infiltration Are Risk Factors for Pancreatic Precancerous Lesions (PanIN)
Vinciane Rebours et al.
CLINICAL CANCER RESEARCH (2015)
Malignant insulinoma may arise during the course of type 1 diabetes mellitus: A case report
S. Lablanche et al.
DIABETES & METABOLISM (2015)
Insulin-like Growth Factor 2 Overexpression Induces β-Cell Dysfunction and Increases Beta-cell Susceptibility to Damage
Alba Casellas et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2015)
Mitochondrial uncoupling protein 2 and pancreatic cancer: A new potential target therapy
Massimo Donadelli et al.
WORLD JOURNAL OF GASTROENTEROLOGY (2015)
Leptin signaling enhances cell invasion and promotes the metastasis of human pancreatic cancer via increasing MMP-13 production
Yingchao Fan et al.
ONCOTARGET (2015)
Aspirin might reduce the incidence of pancreatic cancer: A meta-analysis of observational studies
Yan-Peng Zhang et al.
Scientific Reports (2015)
New insights from monogenic diabetes for common type 2 diabetes
Divya Sri Priyanka Tallapragada et al.
FRONTIERS IN GENETICS (2015)
Stochastic modeling indicates that aging and somatic evolution in the hematopoietic system are driven by non-cell-autonomous processes
Andrii I. Rozhok et al.
AGING-US (2014)
Mitochondrial Retrograde Signaling Mediated by UCP2 Inhibits Cancer Cell Proliferation and Tumorigenesis
Pauline Esteves et al.
CANCER RESEARCH (2014)
Association between the p27 rs2066827 variant and tumor multiplicity in patients harboring MEN1 germline mutations
Viviane C. Longuini et al.
EUROPEAN JOURNAL OF ENDOCRINOLOGY (2014)
ENDOCRINE SIDE EFFECTS OF ANTI-CANCER DRUGS Effects of anti-cancer targeted therapies on lipid and glucose metabolism
Bruno Verges et al.
EUROPEAN JOURNAL OF ENDOCRINOLOGY (2014)
Mechanisms of Obesity-Induced Gastrointestinal Neoplasia
Jose O. Aleman et al.
GASTROENTEROLOGY (2014)
Glutamine Stimulates Biosynthesis and Secretion of Insulin-like Growth Factor 2 (IGF2), an Autocrine Regulator of Beta Cell Mass and Function
Honey Modi et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2014)
Senescence-associated SIN3B promotes inflammation and pancreatic cancer progression
Maite Rielland et al.
JOURNAL OF CLINICAL INVESTIGATION (2014)
Co-existence of insulinoma and diabetes: A case report
Zbigniew Krzysztof Kamocki et al.
ONCOLOGY LETTERS (2014)
GSK3-mediated MAF phosphorylation in multiple myeloma as a potential therapeutic target
N. I. Herath et al.
BLOOD CANCER JOURNAL (2014)
Age-associated changes of islet endocrine cells and the effects of body mass index in Japanese
Hiroki Mizukami et al.
JOURNAL OF DIABETES INVESTIGATION (2014)
Altered MENIN expression disrupts the MAFA differentiation pathway in insulinoma
Z. Hamze et al.
ENDOCRINE-RELATED CANCER (2013)
Inactivation of specific β cell transcription factors in type 2 diabetes
Shuangli Guo et al.
JOURNAL OF CLINICAL INVESTIGATION (2013)
mTOR is a key modulator of ageing and age-related disease
Simon C. Johnson et al.
NATURE (2013)
Prevalence of Diabetes Mellitus in Pancreatic Cancer Compared to Common Cancers
Gaurav Aggarwal et al.
PANCREAS (2013)
PARP-1 and YY1 Are Important Novel Regulators of CXCL12 Gene Transcription in Rat Pancreatic Beta Cells
Jelena Markovic et al.
PLOS ONE (2013)
Whole exome sequencing of insulinoma reveals recurrent T372R mutations in YY1
Yanan Cao et al.
NATURE COMMUNICATIONS (2013)
Dyslipidemia in Obesity: Mechanisms and Potential Targets
Boudewijn Klop et al.
NUTRIENTS (2013)
Pathway analysis of genome-wide association study data highlights pancreatic development genes as susceptibility factors for pancreatic cancer
Donghui Li et al.
CARCINOGENESIS (2012)
EMT and Dissemination Precede Pancreatic Tumor Formation
Andrew D. Rhim et al.
CELL (2012)
Insulin-like growth factor axis and risk of type 2 diabetes in women
Swapnil N. Rajpathak et al.
DIABETES (2012)
Insulinoma may mask the existence of Type 1 diabetes
Y. Oikawa et al.
DIABETIC MEDICINE (2012)
The association of circulating adiponectin levels with pancreatic cancer risk: A study within the prospective EPIC cohort
Verena A. Grote et al.
INTERNATIONAL JOURNAL OF CANCER (2012)
A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance
Alisa K. Manning et al.
NATURE GENETICS (2012)
Cell cycle control of beta-cell replication in the prenatal and postnatal human pancreas
Christina U. Koehler et al.
AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2011)
Clinical implications of discordance between low-density lipoprotein cholesterol and particle number
James D. Otvos et al.
JOURNAL OF CLINICAL LIPIDOLOGY (2011)
Leptin and adiponectin in pancreatic cancer: connection with diabetes mellitus
T. Krechler et al.
NEOPLASMA (2011)
Everolimus for Advanced Pancreatic Neuroendocrine Tumors.
James C. Yao et al.
NEW ENGLAND JOURNAL OF MEDICINE (2011)
Diabetes and Cancer: A Consensus Report
Edward Giovannucci et al.
CA-A CANCER JOURNAL FOR CLINICIANS (2010)
Insulin-Like Growth Factor Axis Gene Polymorphisms and Clinical Outcomes in Pancreatic Cancer
Xiaoqun Dong et al.
GASTROENTEROLOGY (2010)
Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index
Elizabeth K. Speliotes et al.
NATURE GENETICS (2010)
Subcutaneous and visceral adipose tissue: structural and functional differences
M. Mohsen Ibrahim
OBESITY REVIEWS (2010)
The regulation of energy metabolism and the IGF-1/mTOR pathways by the p53 protein
Zhaohui Feng et al.
TRENDS IN CELL BIOLOGY (2010)
Hypermethylation of the IGF2 differentially methylated region 2 is a specific event in insulinomas leading to loss-of-imprinting and overexpression
Emelyne Dejeux et al.
ENDOCRINE-RELATED CANCER (2009)
Antidiabetic Therapies Affect Risk of Pancreatic Cancer
Donghui Li et al.
GASTROENTEROLOGY (2009)
Inherited pancreatic endocrine tumor syndromes: Advances in molecular pathogenesis, diagnosis, management, and controversies
Robert I. Jensen et al.
CANCER (2008)
Pancreatic endocrine neoplasms: epidemiology and prognosis of pancreatic endocrine tumors
Thorvardur R. Halfdanarson et al.
ENDOCRINE-RELATED CANCER (2008)
GSK-3-Mediated phosphorylation enhances Maf-transforming activity
Nathalie Rocques et al.
MOLECULAR CELL (2007)
Roles and regulation of transcription factor MafA in islet β-cells
Shinsaku Aramata et al.
ENDOCRINE JOURNAL (2007)
Glucose infusion in mice -: A new model to induce β-cell replication
Laura C. Alonso et al.
DIABETES (2007)
Co-expression of ghrelin and its receptor in pancreatic endocrine tumours
Sara Ekeblad et al.
CLINICAL ENDOCRINOLOGY (2007)
Common variants in HNF-1 α and risk of type 2 diabetes
J. Holmkvist et al.
DIABETOLOGIA (2006)
Gene expression profiling in insulinomas of Men1 β-cell mutant mice reveals early genetic and epigenetic events involved in pancreatic β-cell tumorigenesis
S. Fontaniere et al.
ENDOCRINE-RELATED CANCER (2006)
Ghrelin and the short- and long-term regulation of appetite and body weight
David E. Cummings
PHYSIOLOGY & BEHAVIOR (2006)
Low insulin-like growth factor-II levels predict weight gain in normal weight subjects with Type 2 diabetes
AH Heald et al.
AMERICAN JOURNAL OF MEDICINE (2006)
MafA is a key regulator of glucose-stimulated insulin secretion
C Zhang et al.
MOLECULAR AND CELLULAR BIOLOGY (2005)
AMP-activated protein kinase: Ancient energy gauge provides clues to modern understanding of metabolism
BB Kahn et al.
CELL METABOLISM (2005)
Insulin resistance is associated with increased cholesterol synthesis and decreased cholesterol absorption in normoglycemic men
J Pihlajamäki et al.
JOURNAL OF LIPID RESEARCH (2004)
Endoplasmic reticulum stress links obesity, insulin action, and type 2 diabetes
U Özcan et al.
SCIENCE (2004)
Cancer incidence in patients with type 1 diabetes mellitus:: A population-based cohort study in Sweden
K Zendehdel et al.
JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE (2003)
Of mice and MEN1: Insulinomas in a conditional mouse knockout
JS Crabtree et al.
MOLECULAR AND CELLULAR BIOLOGY (2003)
Low circulating IGF-II concentrations predict weight gain and obesity in humans
MJS Sandhu et al.
DIABETES (2003)
Telomere shortening is nearly universal in pancreatic intraepithelial neoplasia
NT van Heek et al.
AMERICAN JOURNAL OF PATHOLOGY (2002)
Circulating concentrations of insulin-like growth factor-I and development of glucose intolerance: a prospective observational study
MS Sandhu et al.
LANCET (2002)
Close relation of fasting insulin-like growth factor binding protein-1 (IGFBP-1) with glucose tolerance and cardiovascular risk in two populations
AH Heald et al.
DIABETOLOGIA (2001)
Compensatory responses in mice carrying a null mutation for Ins1 or Ins2
L Leroux et al.
DIABETES (2001)
Different phenotypes of multiple endocrine neoplasia type 1 (MEN1) in monozygotic twins found in a Japanese MEN1 family with MEN1 gene mutation
H Namihira et al.
ENDOCRINE JOURNAL (2000)
Share Paper
