4.3 Article

Developments of Corey-Chaykovsky in Organic Reactions and Total Synthesis of Natural Products

Journal

CURRENT ORGANIC SYNTHESIS
Volume 13, Issue 3, Pages 308-333

Publisher

BENTHAM SCIENCE PUBL LTD
DOI: 10.2174/1570179412666150710182304

Keywords

Corey-Chaykovsky; epoxidation; dimethylsulfoxonium methylide; dimethylsulfonium methylide; organic and total synthesis

Funding

  1. Alzahra Research Council

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The reactions of sulfur ylides with carbonyl, olefin or imine compounds named as the Corey-Chaykovsky, provide oxiranes, cyclopropane or aziridine, respectively. In this report, we try to introduce this important name reaction and highlight a comprehensive overview on the applications of this useful reaction in synthetic organic chemistry and total synthesis of natural products.

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