Journal
CURRENT ORGANIC CHEMISTRY
Volume 20, Issue 18, Pages 1851-1861Publisher
BENTHAM SCIENCE PUBL LTD
DOI: 10.2174/1385272820666160331235258
Keywords
Organocatalysis; desymmetrization; aziridine; azetidine; strained ring
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Funding
- Hong Kong RGC [GRF-604513, M-HKUST607/12, ECS-605812]
- Shenzhen Medical Research Program [201401077]
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Catalytic enantioselective desymmetrization of meso-aziridines and azetidines is a powerful strategy for rapid synthesis of chiral building blocks. This review summarizes the progress in the development of these reactions by organocatalysis.
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