Journal
CURRENT OPINION IN STRUCTURAL BIOLOGY
Volume 40, Issue -, Pages 70-80Publisher
CURRENT BIOLOGY LTD
DOI: 10.1016/j.sbi.2016.07.022
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Funding
- New England Biolabs
- European Union's Seventh Framework Programme under the GlycoBioM [FP7-HEALTH-259869, 1335G00086]
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Experimental techniques to identify and quantify glycan structures in a given sample are continuously improving. However, as they advance data analysis and annotation seems to become more complex. To address this issue, much progress has been made in developing software for interpretation of quantitative glycan profiles. Here, we focus on these informatics tools for high/ultra performance liquid chromatography (H/UPLC), mass spectrometry (MS), tandem mass spectrometry (MSn) and combinations thereof. Software for biomarker discovery, pathway, genomic and disease analysis and a final note on some future prospects for glycoinformatics are also mentioned.
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