Journal
FRONTIERS IN IMMUNOLOGY
Volume 11, Issue -, Pages -Publisher
FRONTIERS MEDIA SA
DOI: 10.3389/fimmu.2020.02130
Keywords
vaccines; emerging infectious diseases; viruses; epidemics; pandemics; antibody-dependent enhancement; SARS-CoV-2; COVID-19
Categories
Funding
- PRIN 2017 NanoTechVax Tackling biological barriers to antigen delivery by nanotechnological vaccines [20173ZECCM]
- Consiglio Nazionale delle Ricerche (CNR), Italy: Laboratori Congiunti Bilaterali Internazionali (Scienze Biomediche), Project: New vaccines against poverty-related and neglected tropical diseases
- CNR, Italy: Laboratori Congiunti Bilaterali Internazionali (Scienze Biomediche), Project: New vaccines against poverty-related and neglected tropical diseases
Ask authors/readers for more resources
In the last decades, a number of infectious viruses have emerged from wildlife or re-emerged, generating serious threats to the global health and to the economy worldwide. Ebola and Marburg hemorrhagic fevers, Lassa fever, Dengue fever, Yellow fever, West Nile fever, Zika, and Chikungunya vector-borne diseases, Swine flu, Severe acute respiratory syndrome (SARS), Middle East respiratory syndrome (MERS), and the recent Coronavirus disease 2019 (COVID-19) are examples of zoonoses that have spread throughout the globe with such a significant impact on public health that the scientific community has been called for a rapid intervention in preventing and treating emerging infections. Vaccination is probably the most effective tool in helping the immune system to activate protective responses against pathogens, reducing morbidity and mortality, as proven by historical records. Under health emergency conditions, new and alternative approaches in vaccine design and development are imperative for a rapid and massive vaccination coverage, to manage a disease outbreak and curtail the epidemic spread. This review gives an update on the current vaccination strategies for some of the emerging/re-emerging viruses, and discusses challenges and hurdles to overcome for developing efficacious vaccines against future pathogens.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available