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Pharmacological blockade of the vanilloid receptor TRPV1 elicits marked hyperthermia in humans
Narender R. Gavva et al.
PAIN (2008)
Protective roles of alpha-calcitonin and beta-calcitonin gene-related peptide in spontaneous and experimentally induced colitis
Brent J. Thompson et al.
DIGESTIVE DISEASES AND SCIENCES (2008)
The transient receptor potential vanilloid 1 (TRPV1) receptor protects against the onset of sepsis after endotoxin
Natalie Clark et al.
FASEB JOURNAL (2007)
Transient receptor potential vanilloid 1 mediates hyperalgesia and is up-regulated in rats with chronic pancreatitis
Guang-Yin Xu et al.
GASTROENTEROLOGY (2007)
4-Hydroxynonenal, an endogenous aldehyde, causes pain and neurogenic inflammation through activation of the irritant receptor TRPA1
Marcello Trevisani et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
The menthol receptor TRPM8 is the principal detector of environmental cold
Diana M. Bautista et al.
NATURE (2007)
Role of calcitonin receptor-like receptor in colonic motility and inflammation
Matthew S. Clifton et al.
AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY (2007)
Role of transient receptor potential vanilloid 1 receptors in endotoxin-induced airway inflammation in the mouse
Zsuzsanna Helyes et al.
AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY (2007)
TRPV1 mediates histamine-induced itching via the activation of phospholipase A2 and 12-lipoxygenase
Won-Sik Shim et al.
JOURNAL OF NEUROSCIENCE (2007)
Protease-activated receptor 2 sensitizes the transient receptor potential vanilloid 4 ion channel to cause mechanical hyperalgesia in mice
Andrew D. Grant et al.
JOURNAL OF PHYSIOLOGY-LONDON (2007)
Transient receptor potential cation channels in disease
Bernd Nilius et al.
PHYSIOLOGICAL REVIEWS (2007)
Diabetic painful neuropathy - Current and future treatment options
M. Sam Chong et al.
DRUGS (2007)
Glial cell line-derived neurotrophic factor family members sensitize nociceptors in vitro and produce thermal hyperalgesia in vivo
Sacha A. Malin et al.
JOURNAL OF NEUROSCIENCE (2006)
Artemin overexpression in skin enhances expression of TRPV1 and TRPA1 in cutaneous sensory neurons and leads to behavioral sensitivity to heat and cold
Christopher M. Elitt et al.
JOURNAL OF NEUROSCIENCE (2006)
TRPA1 mediates the inflammatory actions of environmental irritants and proalgesic agents
DM Bautista et al.
CELL (2006)
Involvement of transient receptor potential vanilloid 1 in the vascular and hyperalgesic components of joint inflammation
J Keeble et al.
ARTHRITIS AND RHEUMATISM (2005)
Dendritic cells do not transduce inflammatory stimuli via the capsaicin receptor TRPV1
PJ O'Connell et al.
FEBS LETTERS (2005)
PI(4,5)P2 regulates the activation and desensitization of TRPM8 channels through the TRP domain
T Rohács et al.
NATURE NEUROSCIENCE (2005)
Sensitization of TRPV1 by EP1 and IP reveals peripheral nociceptive mechanism of prostaglandins
Tomoko Moriyama et al.
MOLECULAR PAIN (2005)
Activation and sensitisation of the vanilloid receptor: role in gastrointestinal inflammation and function
P Geppetti et al.
BRITISH JOURNAL OF PHARMACOLOGY (2004)
Phosphorylation of vanilloid receptor 1 by Ca2+/calmodulin-dependent kinase II regulates its vanilloid binding
JY Jung et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Antitussive activity of iodo-resiniferatoxin in guinea pigs
M Trevisani et al.
THORAX (2004)
Increased capsaicin receptor TRPV1 nerve fibres in the inflamed human oesophagus
PJ Matthews et al.
EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY (2004)
Transient receptor potential vanilloid subfamily 1 expressed in pancreatic islet β cells modulates insulin secretion in rats
Y Akiba et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2004)
Increased expression of transient receptor potential vanilloid-1 in airway nerves of chronic cough
DA Groneberg et al.
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2004)
Human brain endothelium: coexpression and function of vanilloid and endocannabinoid receptors
SA Golech et al.
MOLECULAR BRAIN RESEARCH (2004)
Immunohistochemical evidence of vanilloid receptor 1 in normal human urinary bladder
M Lazzeri et al.
EUROPEAN UROLOGY (2004)
Small-dose capsaicin reduces systemic inflammatory responses in septic rats
S Demirbilek et al.
ANESTHESIA AND ANALGESIA (2004)
Impaired pressure sensation in mice lacking TRPV4
M Suzuki et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Molecular and functional characterization of the melastatin-related cation channel TRPM3
C Grimm et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Capsaicinoids cause inflammation and epithelial cell death through activation of vanilloid receptors
CA Reilly et al.
TOXICOLOGICAL SCIENCES (2003)
Activation of epidermal vanilloid receptor-1 induces release of proinflammatory mediators in human keratinocytes
MD Southall et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2003)
Anandamide and vanilloid TRPV1 receptors
RA Ross
BRITISH JOURNAL OF PHARMACOLOGY (2003)
p38 MAPK activation by NGF in primary sensory neurons after inflammation increases TRPV1 levels and maintains heat hyperalgesia
RR Ji et al.
NEURON (2002)
cAMP-dependent protein kinase regulates desensitization of the capsaicin receptor (VR1) by direct phosphorylation
G Bhave et al.
NEURON (2002)
An endogenous capsaicin-like substance with high potency at recombinant and native vanilloid VR1 receptors
SM Huang et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)
Vanilloid receptor expression suggests a sensory role for urinary bladder epithelial cells
LA Birder et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)
Capsaicin vanilloid receptor-1 mediates substance P release in experimental pancreatitis
JD Nathan et al.
AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY (2001)
Peripheral capsaicin receptors increase in the inflamed rat hindpaw: a possible mechanism for peripheral sensitization
SM Carlton et al.
NEUROSCIENCE LETTERS (2001)
Bradykinin and nerve growth factor release the capsaicin receptor from PtdIns(4,5)P2-mediated inhibition
HH Chuang et al.
NATURE (2001)
Potentiation of capsaicin receptor activity by metabotropic ATP receptors as a possible mechanism for ATP-evoked pain and hyperalgesia
M Tominaga et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)
The TRP ion channel family
DE Clapham et al.
NATURE REVIEWS NEUROSCIENCE (2001)
Identification and characterization of a novel human vanilloid receptor-like protein, VRL-2
NS Delany et al.
PHYSIOLOGICAL GENOMICS (2001)
Direct activation of capsaicin receptors by products of lipoxygenases: Endogenous capsaicin-like substances
SW Hwang et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2000)
Distribution of mRNA for vanilloid receptor subtype 1 (VR1), and VR1-like immunoreactivity, in the central nervous system of the rat and human
É Mezey et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2000)
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