Journal
ENVIRONMENTAL SCIENCE & TECHNOLOGY LETTERS
Volume 7, Issue 12, Pages 937-942Publisher
AMER CHEMICAL SOC
DOI: 10.1021/acs.estlett.0c00730
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Funding
- Water Research Foundation [5029]
- United States National Science Foundation [2027752]
- Intramural Research Program of the National Institute of Allergy and Infectious Diseases, National Institutes of Health
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Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) RNA is frequently detected in the feces of infected individuals. While infectious SARS-CoV-2 has not previously been identified in wastewater, infectious SARS-CoV-2 has been isolated from the feces of at least one patient, raising concerns about the presence of infectious SARS-CoV-2 in wastewater. The fate and inactivation characteristics of SARS-CoV-2 in water and wastewater are unknown, with current inactivation estimates based on surrogate models. In this study, the persistence of SARS-CoV-2 infectivity and RNA signal was determined in water and wastewater. The times for 90% reduction (T-90) of viable SARS-CoV-2 in wastewater and tap water at room temperature were 1.5 and 1.7 days, respectively. In high-starting titer 10(5) TCID50 mL(-1)) experiments, infectious virus persisted for the entire 7-day sampling time course. In wastewater at 50 and 70 degrees C, the observed T-90 values for infectious SARS-CoV-2 were decreased to 15 and 2 min, respectively. SARS-CoV-2 RNA was found to be significantly more persistent than infectious SARS-CoV-2, indicating that the environmental detection of RNA alone does not substantiate risk of infection.
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