4.6 Review

Biocatalytic Oxidation of Alcohols

Journal

CATALYSTS
Volume 10, Issue 9, Pages -

Publisher

MDPI
DOI: 10.3390/catal10090952

Keywords

alcohols; alcohol oxidation; alcohol dehydrogenases; alcohol oxidases; kinetic resolution; deracemization

Funding

  1. European Research Commission (ERC consolidator grant) [648026]
  2. Netherlands Organization for Scientific Research (VICI grant) [724.014.003]
  3. TU Delft
  4. European Research Council (ERC) [648026] Funding Source: European Research Council (ERC)

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Enzymatic methods for the oxidation of alcohols are critically reviewed. Dehydrogenases and oxidases are the most prominent biocatalysts, enabling the selective oxidation of primary alcohols into aldehydes or acids. In the case of secondary alcohols, region and/or enantioselective oxidation is possible. In this contribution, we outline the current state-of-the-art and discuss current limitations and promising solutions.

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