Journal
CURRENT OPINION IN GENETICS & DEVELOPMENT
Volume 41, Issue -, Pages 106-114Publisher
CURRENT BIOLOGY LTD
DOI: 10.1016/j.gde.2016.09.003
Keywords
-
Categories
Funding
- Leverhulme Trust [F/07 134/DF]
- BBSRC [BB/I021213/1]
- Biotechnology and Biological Sciences Research Council [BB/I021213/1] Funding Source: researchfish
- BBSRC [BB/I021213/1] Funding Source: UKRI
Ask authors/readers for more resources
Latin Americans arguably represent the largest recently admixed populations in the world. This reflects a history of massive settlement by immigrants (mostly Europeans and Africans) and their variable admixture with Natives, starting in 1492. This process resulted in the population of Latin America showing an extensive genetic and phenotypic diversity. Here we review how genetic analyses are being applied to examine the demographic history of this population, including patterns of mating, population structure and ancestry. The admixture history of Latin America, and the resulting extensive diversity of the region, represents a natural experiment offering an advantageous setting for genetic association studies. We review how recent analyses in Latin Americans are contributing to elucidating the genetic architecture of human complex traits.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available