Bamford-Stevens and Shapiro Reactions in Organic Synthesis

Total synthesis of natural products often requires installation of double bond without adding carbon. Bamford-Stevens and Shapiro reactions offer an option to execute such transformation. Several developments have been made in these reactions and their applications in a diverse area of chemistry. Lack of a dedicated review on these reactions in the recent time is hampering an access to collective information and a critical analysis of the new developments. This minireview highlights methodological developments and applications of Bamford-Stevens and Shapiro reactions in organic synthesis published in the past ten years.