4.7 Review

The function and regulation of TET2 in innate immunity and inflammation

Related references

Note: Only part of the references are listed.
Article Biochemistry & Molecular Biology

14-3-3 proteins protect AMPK-phosphorylated ten-eleven translocation-2 (TET2) from PP2A-mediated dephosphorylation

Anirban Kundu et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2020)

Article Immunology

Tet2 and Tet3 in B cells are required to repress CD86 and prevent autoimmunity

Shinya Tanaka et al.

NATURE IMMUNOLOGY (2020)

Article Multidisciplinary Sciences

TET1 is an important transcriptional activator of TNFα expression in macrophages

Fangfang Sun et al.

PLOS ONE (2019)

Article Multidisciplinary Sciences

Dual mechanisms of posttranscriptional regulation of Tet2 by Let-7 microRNA in macrophages

Shuai Jiang et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2019)

Article Genetics & Heredity

Phosphorylation of TET2 by AMPK is indispensable in myogenic differentiation

Ting Zhang et al.

EPIGENETICS & CHROMATIN (2019)

Article Multidisciplinary Sciences

Loss of TET2 and TET3 in regulatory T cells unleashes effector function

Xiaojing Yue et al.

NATURE COMMUNICATIONS (2019)

Article Cell Biology

OxLDL induces vascular endothelial cell pyroptosis through miR-125a-5p/TET2 pathway

Zeng Zhaolin et al.

JOURNAL OF CELLULAR PHYSIOLOGY (2019)

Article Biochemistry & Molecular Biology

p53-dependent autophagic degradation of TET2 modulates cancer therapeutic resistance

Jixiang Zhang et al.

ONCOGENE (2019)

Article Multidisciplinary Sciences

miRNA142-3p targets Tet2 and impairs Treg differentiation and stability in models of type 1 diabetes

Martin G. Scherm et al.

NATURE COMMUNICATIONS (2019)

Review Immunology

TET Enzymes and 5hmC in Adaptive and Innate Immune Systems

Chan-Wang J. Lio et al.

FRONTIERS IN IMMUNOLOGY (2019)

Review Immunology

Epigenetic regulation of the innate immune response to infection

Qian Zhang et al.

NATURE REVIEWS IMMUNOLOGY (2019)

Article Medicine, Research & Experimental

Epigenetic modulation of β cells by interferon-α via PNPT1/mir-26a/TET2 triggers autoimmune diabetes

Mihaela Stefan-Lifshitz et al.

JCI INSIGHT (2019)

Article Multidisciplinary Sciences

Tet2 promotes pathogen infection-induced myelopoiesis through mRNA oxidation

Qicong Shen et al.

NATURE (2018)

Article Biochemistry & Molecular Biology

Acetylation Enhances TET2 Function in Protecting against Abnormal DNA Methylation during Oxidative Stress

Yang W. Zhang et al.

MOLECULAR CELL (2017)

Review Genetics & Heredity

TET-mediated active DNA demethylation: mechanism, function and beyond

Xiaoji Wu et al.

NATURE REVIEWS GENETICS (2017)

Article Biochemistry & Molecular Biology

Nickel(II) Inhibits Tet-Mediated 5-Methylcytosine Oxidation by High Affinity Displacement of the Cofactor Iron(II)

Ruichuan Yin et al.

ACS CHEMICAL BIOLOGY (2017)

Article Immunology

Control of Foxp3 stability through modulation of TET activity

Xiaojing Yue et al.

JOURNAL OF EXPERIMENTAL MEDICINE (2016)

Article Biochemistry & Molecular Biology

High-Resolution Mapping of RNA-Binding Regions in the Nuclear Proteome of Embryonic Stem Cells

Chongsheng He et al.

MOLECULAR CELL (2016)

Article Multidisciplinary Sciences

Retinol and ascorbate drive erasure of epigenetic memory and enhance reprogramming to naive pluripotency by complementary mechanisms

Timothy Alexander Hore et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2016)

Article Cell Biology

TET3 Inhibits Type I IFN Production Independent of DNA Demethylation

Shengjie Xue et al.

CELL REPORTS (2016)

Article Biochemistry & Molecular Biology

CRL4VprBP E3 Ligase Promotes Monoubiquitylation and Chromatin Binding of TET Dioxygenases

Tadashi Nakagawa et al.

MOLECULAR CELL (2015)

Article Biochemistry & Molecular Biology

WT1 Recruits TET2 to Regulate Its Target Gene Expression and Suppress Leukemia Cell Proliferation

Yiping Wang et al.

MOLECULAR CELL (2015)

Review Immunology

Epigenetic control of myeloid cell differentiation, identity and function

Damiana Alvarez-Errico et al.

NATURE REVIEWS IMMUNOLOGY (2015)

Article Chemistry, Multidisciplinary

Tet-Mediated Formation of 5-Hydroxymethylcytosine in RNA

Lijuan Fu et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2014)

Article Cell Biology

Regulation of TET Protein Stability by Calpains

Yu Wang et al.

CELL REPORTS (2014)

Article Cardiac & Cardiovascular Systems

Ten-Eleven Translocation-2 (TET2) Is a Master Regulator of Smooth Muscle Cell Plasticity

Renjing Liu et al.

CIRCULATION (2013)

Article Biochemistry & Molecular Biology

Ascorbate Induces Ten-Eleven Translocation (Tet) Methylcytosine Dioxygenase-mediated Generation of 5-Hydroxymethylcytosine

Emily A. Minor et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2013)

Article Multidisciplinary Sciences

Vitamin C induces Tet-dependent DNA demethylation and a blastocyst-like state in ES cells

Kathryn Blaschke et al.

NATURE (2013)

Review Genetics & Heredity

DNA methylation: roles in mammalian development

Zachary D. Smith et al.

NATURE REVIEWS GENETICS (2013)

Review Cell Biology

TETonic shift: biological roles of TET proteins in DNA demethylation and transcription

William A. Pastor et al.

NATURE REVIEWS MOLECULAR CELL BIOLOGY (2013)

Article Immunology

The resolution of inflammation

Christopher D. Buckley et al.

NATURE REVIEWS IMMUNOLOGY (2013)

Article Immunology

The history of Toll-like receptors - redefining innate immunity

Luke A. J. O'Neill et al.

NATURE REVIEWS IMMUNOLOGY (2013)

Review Genetics & Heredity

Functions of DNA methylation: islands, start sites, gene bodies and beyond

Peter A. Jones

NATURE REVIEWS GENETICS (2012)

Review Immunology

The epigenetics of autoimmunity

Francesca Meda et al.

CELLULAR & MOLECULAR IMMUNOLOGY (2011)

Article Multidisciplinary Sciences

Tet Proteins Can Convert 5-Methylcytosine to 5-Formylcytosine and 5-Carboxylcytosine

Shinsuke Ito et al.

SCIENCE (2011)

Review Biochemistry & Molecular Biology

Physiological and biochemical aspects of hydroxylations and demethylations catalyzed by human 2-oxoglutarate oxygenases

Christoph Loenarz et al.

TRENDS IN BIOCHEMICAL SCIENCES (2011)

Article Biochemistry & Molecular Biology

Epigenetics: deciphering how environmental factors may modify autoimmune type 1 diabetes

Amanda J. MacFarlane et al.

MAMMALIAN GENOME (2009)

Article Genetics & Heredity

Acquired mutations in TET2 are common in myelodysplastic syndromes

Saskia M. C. Langemeijer et al.

NATURE GENETICS (2009)

Article Medicine, General & Internal

Mutation in TET2 in Myeloid Cancers

Francois Delhommeau et al.

NEW ENGLAND JOURNAL OF MEDICINE (2009)

Review Multidisciplinary Sciences

Origin and physiological roles of inflammation

Ruslan Medzhitov

NATURE (2008)