Journal
CURRENT OPINION IN CELL BIOLOGY
Volume 40, Issue -, Pages 90-97Publisher
CURRENT BIOLOGY LTD
DOI: 10.1016/j.ceb.2016.03.001
Keywords
-
Categories
Funding
- Norwegian Cancer Society [605009]
- Research Council of Norway through its Centres of Excellence [179571]
Ask authors/readers for more resources
The nuclear envelope (NE) ensures nucleo-cytoplasmic compartmentalization, with trafficking of macromolecules across this double membrane controlled by embedded nuclear pore complexes (NPCs). The NE and associated proteins are dismantled during open mitosis and reestablishment of this barrier during mitotic exit requires dynamic remodeling of endoplasmic reticulum (ER) membranes and coordination with NPC reformation, with NPC deposition continuing during subsequent interphase. In this review, we discuss recent progress in our understanding of NE reformation and nuclear pore complex generation, with special focus on work implicating the endosomal sorting complex required for transport (ESCRT) membrane remodeling machinery in these events.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available