Journal
CURRENT OPINION IN BIOTECHNOLOGY
Volume 40, Issue -, Pages 1-8Publisher
ELSEVIER SCI LTD
DOI: 10.1016/j.copbio.2016.02.001
Keywords
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Funding
- NIH [R01 EB015498]
- HHMI ISRF
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Cancer immunotherapy is becoming a standard approach to treat many cancers. However, shortcomings of current methods limit therapeutic benefit in many patients. Rationally designed biomaterial strategies to deliver immune modulatory drugs can potentially show improved safety profiles, while providing multifunctional and spatiotemporally controlled signals to immune cells to improve their anticancer activity. This brief review describes biomaterialsbased strategies that enhance immune cell function at various tissue sites to improve anti-cancer immunity. Continued collaboration between bioengineers, immunologists, industry, and clinicians is required for biomaterial-based immunotherapy strategies to continue moving to the clinic.
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