4.5 Article

Evaluation of a midwife-led, hospital based vaccination service for pregnant women

Journal

HUMAN VACCINES & IMMUNOTHERAPEUTICS
Volume 17, Issue 1, Pages 237-246

Publisher

TAYLOR & FRANCIS INC
DOI: 10.1080/21645515.2020.1770515

Keywords

Pregnancy; maternal vaccination; ethnicity; midwives

Funding

  1. National Institute for Health Research (NIHR) Biomedical Research Centre based at Imperial College Healthcare NHS Trust and Imperial College London
  2. IMmunising PRegnant women and INfants neTwork (IMPRINT) - UKRI-GCRF Networks in Vaccines Research and Development
  3. MRC
  4. BBSRC
  5. MRC [MC_PC_17221, MR/R005990/2] Funding Source: UKRI

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The study found that reasons for vaccine decline among pregnant women seen in a hospital midwife-led vaccine clinic were categorized by themes. Fewer Black Afro-Caribbean women were vaccinated compared to other ethnicities, with midwives' reassurance being the most important factor influencing maternal vaccine decisions.
Background Vaccines against whooping cough (pertussis) and seasonal-influenza are recommended for pregnant women in England. Uptake however varies regionally and by ethnicity. Pregnant women are traditionally vaccinated in primary care, though some hospitals now offer vaccines through antenatal clinics. This mixed-methods evaluation describes the demographic characteristics of women seen in a hospital midwife-led antenatal vaccine clinic and explores vaccine decision making. Methods Descriptive statistics of women seen in a London hospital's midwife-led vaccine clinic were generated from electronic routine maternity records, including data on ethnicity, parity, age and deprivation indices. Reasons for vaccine decline given by women to midwives were categorized by themes. Qualitative interviews of women seen in the clinic were also undertaken. Results Between 1st April 2017 and 31st March 2018 the vaccine clinic saw 1501 pregnant women. Of these, 83% received pertussis vaccine and (during flu season) 51% received influenza vaccine, from the clinic. Fewer Black Afro-Caribbean women seen by the clinic were vaccinated, compared to other ethnicities with only 68% receiving pertussis and 34% flu vaccines respectively (p< .05). Among all women delivering at the hospital over the year, 42%, (1334/3147) were vaccinated by the clinic. Qualitative interviews found that reassurance from healthcare professionals, particularly midwives, was the most important factor influencing maternal vaccine decisions. Conclusions Midwife-led hospital clinics can offer an effective alternative to primary care provision for vaccines in pregnancy. Consistent with previous work, vaccine uptake varied by ethnicity. Midwives play a key role in the provision of vaccine services and influence women's vaccine decisions.

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