Journal
CURRENT NEUROLOGY AND NEUROSCIENCE REPORTS
Volume 16, Issue 6, Pages -Publisher
SPRINGER
DOI: 10.1007/s11910-016-0658-1
Keywords
ALS; Genetics; Motor neuron diseases
Categories
Ask authors/readers for more resources
Amyotrophic lateral sclerosis (ALS) is a fatal disorder that is characterized by a progressive degeneration of the upper and lower motor neurons. Most cases appear to be sporadic, but 5-10% of cases have a family history of the disease. High-throughput DNA sequencing and related genomic capture tools are methodological advances which have rapidly contributed to an acceleration in the discovery of genetic risk factors for both familial and sporadic ALS. It is interesting to note that as the number of ALS genes grows, many of the proteins they encode are in shared intracellular processes. This review will summarize some of the recent advances and gene discovery made in ALS.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available