Journal
NUTRIENTS
Volume 12, Issue 9, Pages -Publisher
MDPI
DOI: 10.3390/nu12092670
Keywords
animal-derived protein; plant-derived protein; collagen-derived protein; protein blends; skeletal muscle; bone; ageing; exercise; energy restriction
Categories
Funding
- MRC Versus Arthritis Centre for Musculoskeletal Ageing Research [MR/P021220/1, MR/R502364/1]
- National Institute for Health Research Nottingham Biomedical Research Centre [MR/T026014/1]
- MRC [MR/T026014/1] Funding Source: UKRI
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Dietary protein is critical for the maintenance of musculoskeletal health, where appropriate intake (i.e., source, dose, timing) can mitigate declines in muscle and bone mass and/or function. Animal-derived protein is a potent anabolic source due to rapid digestion and absorption kinetics stimulating robust increases in muscle protein synthesis and promoting bone accretion and maintenance. However, global concerns surrounding environmental sustainability has led to an increasing interest in plant- and collagen-derived protein as alternative or adjunct dietary sources. This is despite the lower anabolic profile of plant and collagen protein due to the inferior essential amino acid profile (e.g., lower leucine content) and subordinate digestibility (versus animal). This review evaluates the efficacy of animal-, plant- and collagen-derived proteins in isolation, and as protein blends, for augmenting muscle and bone metabolism and health in the context of ageing, exercise and energy restriction.
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