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Progress in exosomes and their potential use in ocular diseases

Journal

INTERNATIONAL JOURNAL OF OPHTHALMOLOGY
Volume 13, Issue 9, Pages 1493-1498

Publisher

IJO PRESS
DOI: 10.18240/ijo.2020.09.23

Keywords

exosomes; ocular diseases; progress; treatment

Categories

Funding

  1. National Natural Science Foundation of China [81470633]
  2. Natural Science Grant of the Heilongjiang Province of China [H2018035]
  3. Innovation and Development Foundation of the First Affiliated Hospital of Harbin Medical University [2018L002]

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Exosomes contain a variety of biological active substances such as proteins, miRNAs, lncRNAs and lipids, and exosomes from different cells play different biological functions. Exosomes, as a carrier, are involved in many pathological processes such as nerve injury and repair, vascular regeneration, immune response, and fibrosis formation. It plays an important role in the treatment of eye diseases such as glaucoma, diabetic retinopathy, and keratitis. This paper reviews the research progress of exosomes in various diseases in vivo, which provides a new way for the treatment of eye diseases.

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