Related references
Note: Only part of the references are listed.Fragment-to-Lead Medicinal Chemistry Publications in 2018
Daniel A. Erlanson et al.
JOURNAL OF MEDICINAL CHEMISTRY (2020)
α-Ketoamides as Broad-Spectrum Inhibitors of Coronavirus and Enterovirus Replication: Structure-Based Design, Synthesis, and Activity Assessment
Linlin Zhang et al.
JOURNAL OF MEDICINAL CHEMISTRY (2020)
Structure-based design of antiviral drug candidates targeting the SARS-CoV-2 main protease
Wenhao Dai et al.
SCIENCE (2020)
Structure of Mpro from SARS-CoV-2 and discovery of its inhibitors
Zhenming Jin et al.
NATURE (2020)
NMR quality control of fragment libraries for screening
Sridhar Sreeramulu et al.
JOURNAL OF BIOMOLECULAR NMR (2020)
Crystallographic and electrophilic fragment screening of the SARS-CoV-2 main protease
Alice Douangamath et al.
NATURE COMMUNICATIONS (2020)
Advances in covalent kinase inhibitors
Ayah Abdeldayem et al.
CHEMICAL SOCIETY REVIEWS (2020)
The Alkyne Moiety as a Latent Electrophile in Irreversible Covalent Small Molecule Inhibitors of Cathepsin K
Elma Mons et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2019)
Rapid Covalent-Probe Discovery by Electrophile-Fragment Screening
Efrat Resnick et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2019)
Discovery and characterization of highly potent and selective allosteric USP7 inhibitors
Gerald Gavory et al.
NATURE CHEMICAL BIOLOGY (2018)
7-Azaindole: A Versatile Scaffold for Developing Kinase Inhibitors
Takayuki Irie et al.
CHEMICAL & PHARMACEUTICAL BULLETIN (2018)
Discovery of Mcl-1-specific inhibitor AZD5991 and preclinical activity in multiple myeloma and acute myeloid leukemia
Adriana E. Tron et al.
NATURE COMMUNICATIONS (2018)
Discovery of Small-Molecule Inhibitors of Ubiquitin Specific Protease 7 (USP7) Using Integrated NMR and in Silico Techniques
Paola Di Lello et al.
JOURNAL OF MEDICINAL CHEMISTRY (2017)
Twenty years on: the impact of fragments on drug discovery
Daniel A. Erlanson et al.
NATURE REVIEWS DRUG DISCOVERY (2016)
Discovery of a selective inhibitor of oncogenic B-Raf kinase with potent antimelanoma activity
James Tsai et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
An inhibitor of Bcl-2 family proteins induces regression of solid tumours
T Oltersdorf et al.
NATURE (2005)