Journal
WORLD JOURNAL OF PEDIATRICS
Volume 17, Issue 2, Pages 123-130Publisher
ZHEJIANG UNIV SCH MEDICINE
DOI: 10.1007/s12519-020-00379-9
Keywords
Kasabach-Merritt phenomenon; Kaposiform hemangioendothelioma; Tufted hemangioma
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Kasabach-Merritt phenomenon is a rare disease characterized by severe thrombocytopenia and consumptive coagulation dysfunction caused by specific types of hemangiomas. This review introduces standardized recommendations for the pathogenesis, diagnosis, and treatment of KMP in China, offering valuable insights for clinical practice.
Kasabach-Merritt phenomenon (KMP) is a rare disease that is characterized by severe thrombocytopenia and consumptive coagulation dysfunction caused by kaposiform hemangioendothelioma or tufted hemangioma. This condition primarily occurs in infants and young children, usually with acute onset and rapid progression. This review article introduced standardized recommendations for the pathogenesis, clinical manifestation, diagnostic methods and treatment process of KMP in China, which can be used as a reference for clinical practice.
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