4.5 Article

COVID-19-A vascular disease

Journal

TRENDS IN CARDIOVASCULAR MEDICINE
Volume 31, Issue 1, Pages 1-5

Publisher

ELSEVIER SCIENCE LONDON
DOI: 10.1016/j.tcm.2020.10.005

Keywords

Endothelium; Coagulation; Thrombosis; Inflammation; Microvessels

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SARS-CoV-2 causes multi-system dysfunction, with emerging evidence indicating that endothelial injury plays a crucial role. Therapies targeting vascular system dysfunction may be important in treating SARS-CoV-2 infection and its long-lasting effects.
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) leads to multi-system dysfunction with emerging evidence suggesting that SARS-CoV-2-mediated endothelial injury is an important effector of the virus. Potential therapies that address vascular system dysfunction and its sequelae may have an important role in treating SARS-CoV-2 infection and its long-lasting effects. (C) 2020 Elsevier Inc. All rights reserved.

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