Journal
TETRAHEDRON
Volume 76, Issue 48, Pages -Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tet.2020.131662
Keywords
Sulfonamide; Synthesis; Mechanism; Synthetic applications; Biological applications
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Funding
- Science and Engineering Research Board, Department of Science and Technology, Government of India [ECR/2017/000537]
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A sulfonamide is a functional group that is the basis of several sulfa drugs and thereby are very much important scaffolds in medicinal as well as in synthetic organic chemistry. Recently very important methodologies have been developed for the synthesis of sulfonamide. This complex review article covers the recent developments (mainly in the period 2013-2019) of powerful methodologies for the synthesis of sulfonamide compounds, particularly where SO2N(R) moiety is not present in a cyclic structure and their applications in various fields during this period. A critical view of the mechanisms of the developed methodologies together with the scope and limitation of these methods adds an extra dimension to the text. (C) 2020 Elsevier Ltd. All rights reserved.
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