Recent Advances in Copper-Catalyzed Radical C-H Bond Activation Using N-F Reagents

This Short Review is aimed at giving an update in the area of copper-catalyzed C-H functionalization involving nitrogen-centered radicals generated from substrates containing N-F bonds. These processes include intermolecular Csp(3)-H bond functionalization, remote Csp(3)-H bond functionalization via intramolecular hydrogen atom transfer (HAT), and Csp(2)-H bond functionalization, which might be of potential use in industrial applications in the future.

Automated summary

This Short Review provides an update on copper-catalyzed C-H functionalization involving nitrogen-centered radicals from substrates containing N-F bonds. The processes discussed include intermolecular Csp(3)-H bond functionalization, remote Csp(3)-H bond functionalization via intramolecular hydrogen atom transfer (HAT), and Csp(2)-H bond functionalization, showing potential for future industrial applications.