Journal
SMALL
Volume 16, Issue 43, Pages -Publisher
WILEY-V C H VERLAG GMBH
DOI: 10.1002/smll.202004132
Keywords
adhesive coacervates; antimicrobial properties; coacervation; hydrogen bonding; wet adhesion
Categories
Funding
- Natural Sciences and Engineering Research Council of Canada (NSERC)
- Canada Research Chairs Program
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Coacervation plays a critical role in numerous biological activities such as constructing biological tissues and achieving robust wet adhesion of marine sessile organisms, which conventionally occurs when oppositely charged polyelectrolytes are mixed in aqueous solutions driven by electrostatic attraction. Here, a novel type of adhesive coacervate is reported, driven by hydrogen-bonding interactions, readily formed by mixing silicotungstic acid and nonionic polyethylene glycol in water, providing a new approach for developing coacervates from nonionic systems. The as-prepared coacervate is easily paintable underwater, show strong wet adhesion to diverse substrates, and has been successfully applied as a hemostatic agent to treat organ injuries without displaying hemolytic activity, while with inherent antimicrobial properties thus avoiding inflammations and infections due to microorganism accumulation. This work demonstrates that coacervation can occur in salt-free environments via non-electrostatic interactions, providing a new platform for engineering multifunctional coacervate materials as tissue glues, wound dressings and membrane-free cell systems.
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