Journal
SEMINARS IN PEDIATRIC SURGERY
Volume 29, Issue 5, Pages -Publisher
ELSEVIER SCIENCE INC
DOI: 10.1016/j.sempedsurg.2020.150966
Keywords
Vascular anomaly; Vascular malformation; Coagulopathy; Kasabach-Merritt phenomenon; Anticoagulation
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Vascular anomalies, comprised of vascular tumors and malformations, are frequently associated with co-agulopathy. Recognition of and familiarity with these vascular anomaly-associated hematologic abnormalities prior to surgery or interventional procedures is essential for pre-operative pre-operative planning. Complicated coagulopathies present within the framework of either Kasabach-Merritt phenomenon (KMP) or localized intravascular coagulopathy (LIC), and their management benefits from the expertise of a hematologist for optimal intra- and peri-operative care. Furthermore, with the recent broadening of understanding of vascular anomalies and the addition of new classification sub-groups, distinctions of these two classic coagulopathy phenotypes have been recognized. This review summarizes the main features of these coagulopathies, described according to their vascular anomaly type, highlighting clinical aspects relevant to surgical management. (C) 2020 Elsevier Inc. All rights reserved.
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