4.6 Review

25 years of research put RIPK1 in the clinic

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DAI/ZBP1 recruits RIP1 and RIP3 through RIP homotypic interaction motifs to activate NF-κB

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Ubiquitination of RIP is required for tumor necrosis factor α-induced NF-κB activation

HX Li et al.

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MORT1/FADD is involved in liver regeneration

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Activation of caspases-8 and-10 by FLIPL

KM Boatright et al.

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TAB2 and TAB3 activate the NF-κB pathway through binding to polyubiquitin chains

A Kanayama et al.

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A FADD-dependent innate immune mechanism in mammalian cells

S Balachandran et al.

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Induction of TNF receptor I-mediated apoptosis via two sequential signaling complexes

O Micheau et al.

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The long form of FLIP is an activator of caspase-8 at the fas death-inducing signaling complex

O Micheau et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2002)