4.4 Letter

Use of the kinetically-derived maximum dose: Opportunities for delivering 3Rs benefits

Journal

REGULATORY TOXICOLOGY AND PHARMACOLOGY
Volume 116, Issue -, Pages -

Publisher

ACADEMIC PRESS INC ELSEVIER SCIENCE
DOI: 10.1016/j.yrtph.2020.104734

Keywords

3Rs; Reduction; Refinement; Dose selection; Kinetically-derived Maximum Dose (KMD); Limit dose; Maximum Tolerated Dose (MTD)

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