Familial Mediterranean fever: clinical state of the art

As the inflammation research improves year-by-year, so does our understanding of the autoinflammatory conditions. Over the past years, the number of monogenic autoinflammatory conditions snowballed thanks to our understanding of basic immunology and genetics. Familial Mediterranean fever (FMF), being the entrance to this fascinating world, still has clinical relevance as it enables us to understand our approach to these patients, treatment modalities and pathological mechanisms. This review can be used as a tool for clinicians already working with FMF patients to update themselves on recent scientific literature.

Automated summary

As inflammation research improves, our understanding of autoinflammatory conditions also increases. Familial Mediterranean fever (FMF), being the entrance to this field, is still clinically relevant for our understanding of patient management, treatment options, and underlying mechanisms.