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BLOOD (2014)
miR-96 and miR-330 overexpressed and targeted AQP5 in lipopolysaccharide-induced rat lung damage of disseminated intravascular coagulation
Yanfen Zhang et al.
BLOOD COAGULATION & FIBRINOLYSIS (2014)
Treatment of Acute Venous Thromboembolism With Dabigatran or Warfarin and Pooled Analysis
Sam Schulman et al.
CIRCULATION (2014)
Serum miR-122 levels are related to coagulation disorders in sepsis patients
Hui-Juan Wang et al.
CLINICAL CHEMISTRY AND LABORATORY MEDICINE (2014)
Development of microRNA therapeutics is coming of age
Eva van Rooij et al.
EMBO MOLECULAR MEDICINE (2014)
Rare bleeding disorders - bleeding assessment tools, laboratory aspects and phenotype and therapy of FXI deficiency
P. James et al.
HAEMOPHILIA (2014)
MicroRNA-19b functions as potential anti-thrombotic protector in patients with unstable angina by targeting tissue factor
Sufang Li et al.
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (2014)
Let-7g Improves Multiple Endothelial Functions Through Targeting Transforming Growth Factor-Beta and SIRT-1 Signaling
Yi-Chu Liao et al.
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2014)
Antigen levels of coagulation factor XII, coagulation factor XI and prekallikrein, and the risk of myocardial infarction and ischemic stroke in young women
B. Siegerink et al.
JOURNAL OF THROMBOSIS AND HAEMOSTASIS (2014)
MicroRNAs in Atherosclerosis
Ali A. Hosin et al.
JOURNAL OF VASCULAR RESEARCH (2014)
Identification of miRNA-21 and miRNA-24 in plasma as potential early stage markers of acute cerebral infarction
Jiansuo Zhou et al.
MOLECULAR MEDICINE REPORTS (2014)
The multilayered complexity of ceRNA crosstalk and competition
Yvonne Tay et al.
NATURE (2014)
Regulation of Coagulation Factor XI Expression by MicroRNAs in the Human Liver
Salam Salloum-Asfar et al.
PLOS ONE (2014)
MicroRNA-155 and microRNA-196b: promising biomarkers in hepatitis C virus infection
Ewelina Maria Kaluzna
REVIEWS IN MEDICAL VIROLOGY (2014)
A Factor XIIa Inhibitory Antibody Provides Thromboprotection in Extracorporeal Circulation Without Increasing Bleeding Risk
Magnus Larsson et al.
SCIENCE TRANSLATIONAL MEDICINE (2014)
MiR-143/145 deficiency attenuates the progression of atherosclerosis in Ldlr-/- mice
Federica Sala et al.
THROMBOSIS AND HAEMOSTASIS (2014)
ELAVL1 Modulates Transcriptome-wide miRNA Binding in Murine Macrophages
Yi-Chien Lu et al.
CELL REPORTS (2014)
Epidemiologic and clinical data linking factors XI and XII to thrombosis
Nigel S. Key
HEMATOLOGY-AMERICAN SOCIETY OF HEMATOLOGY EDUCATION PROGRAM (2014)
Oral rivaroxaban versus enoxaparin with vitamin K antagonist for the treatment of symptomatic venous thromboembolism in patients with cancer (EINSTEIN-DVT and EINSTEIN-PE): a pooled subgroup analysis of two randomised controlled trials
Martin H. Prins et al.
LANCET HAEMATOLOGY (2014)
Molecular Mechanisms of RNA Interference
Ross C. Wilson et al.
ANNUAL REVIEW OF BIOPHYSICS, VOL 42 (2013)
Antithrombotic Effect of Antisense Factor XI Oligonucleotide Treatment in Primates
Jeffrey R. Crosby et al.
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2013)
Circulating miR-30a, miR-126 and let-7b as biomarker for ischemic stroke in humans
Guangwen Long et al.
BMC NEUROLOGY (2013)
Importance of Pharmacokinetic Profile and Variability as Determinants of Dose and Response to Dabigatran, Rivaroxaban, and Apixaban
Inna Y. Gong et al.
CANADIAN JOURNAL OF CARDIOLOGY (2013)
Differential MicroRNA Expression Profiles in Peripheral Arterial Disease
Philip W. Stather et al.
CIRCULATION-CARDIOVASCULAR GENETICS (2013)
Pathologies at the nexus of blood coagulation and inflammation: thrombin in hemostasis, cancer, and beyond
Sven Danckwardt et al.
JOURNAL OF MOLECULAR MEDICINE-JMM (2013)
MicroRNAs in platelet production and activation
L. C. Edelstein et al.
JOURNAL OF THROMBOSIS AND HAEMOSTASIS (2013)
Assessing bleeding risk in patients taking anticoagulants
Marwa Shoeb et al.
JOURNAL OF THROMBOSIS AND THROMBOLYSIS (2013)
Systemically Injected Exosomes Targeted to EGFR Deliver Antitumor MicroRNA to Breast Cancer Cells
Shin-ichiro Ohno et al.
MOLECULAR THERAPY (2013)
Argonaute proteins: functional insights and emerging roles
Gunter Meister
NATURE REVIEWS GENETICS (2013)
Antisense Oligonucleotides: Treating Neurodegeneration at the Level of RNA
Sarah L. DeVos et al.
NEUROTHERAPEUTICS (2013)
Dabigatran versus Warfarin in Patients with Mechanical Heart Valves
John W. Eikelboom et al.
NEW ENGLAND JOURNAL OF MEDICINE (2013)
Treatment of HCV Infection by Targeting MicroRNA
Harry L. A. Janssen et al.
NEW ENGLAND JOURNAL OF MEDICINE (2013)
Edoxaban versus Warfarin for the Treatment of Symptomatic Venous Thromboembolism
Harry R. Bueller et al.
NEW ENGLAND JOURNAL OF MEDICINE (2013)
Edoxaban versus Warfarin in Patients with Atrial Fibrillation
Robert P. Giugliano et al.
NEW ENGLAND JOURNAL OF MEDICINE (2013)
Oral Apixaban for the Treatment of Acute Venous Thromboembolism
Giancarlo Agnelli et al.
NEW ENGLAND JOURNAL OF MEDICINE (2013)
Congenital Factor XI Deficiency: An Update
Stefano Duga et al.
SEMINARS IN THROMBOSIS AND HEMOSTASIS (2013)
Anticoagulation beyond direct thrombin and factor Xa inhibitors: indications for targeting the intrinsic pathway?
Maurits L. van Montfoort et al.
THROMBOSIS AND HAEMOSTASIS (2013)
siRNA Genome Screening Approaches to Therapeutic Drug Repositioning
Olivia Perwitasari et al.
PHARMACEUTICALS (2013)
RNAi-based nanomedicines for targeted personalized therapy
Ala Daka et al.
ADVANCED DRUG DELIVERY REVIEWS (2012)
A Genome-Wide Association Study Identifies KNG1 as a Genetic Determinant of Plasma Factor XI Level and Activated Partial Thromboplastin Time
Maria Sabater-Lleal et al.
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2012)
Antisense inhibition of coagulation factor XI prolongs APTT without increased bleeding risk in cynomolgus monkeys
Husam S. Younis et al.
BLOOD (2012)
Dissection of human MiRNA regulatory influence to subpathway
Xia Li et al.
BRIEFINGS IN BIOINFORMATICS (2012)
Global and regional mortality from 235 causes of death for 20 age groups in 1990 and 2010: a systematic analysis for the Global Burden of Disease Study 2010
Rafael Lozano et al.
LANCET (2012)
Atheroprotective communication between endothelial cells and smooth muscle cells through miRNAs
Eduard Hergenreider et al.
NATURE CELL BIOLOGY (2012)
RNA therapeutics: beyond RNA interference and antisense oligonucleotides
Ryszard Kole et al.
NATURE REVIEWS DRUG DISCOVERY (2012)
The mechanics of miRNA-mediated gene silencing: a look under the hood of miRISC
Marc R. Fabian et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2012)
Rivaroxaban in Patients with a Recent Acute Coronary Syndrome
Jessica L. Mega et al.
NEW ENGLAND JOURNAL OF MEDICINE (2012)
miR-421 and miR-30c Inhibit SERPINE 1 Gene Expression in Human Endothelial Cells
Alexandre Marchand et al.
PLOS ONE (2012)
Circulating miR-30a, miR-195 and let-7b Associated with Acute Myocardial Infarction
Guangwen Long et al.
PLOS ONE (2012)
Factor XI: Hemostasis, Thrombosis, and Antithrombosis
Rong He et al.
THROMBOSIS RESEARCH (2012)
Circulating microRNA-126 in patients with coronary artery disease: correlation with LDL cholesterol
Xiao Sun et al.
THROMBOSIS JOURNAL (2012)
miR-21, miR-210, miR-34a, and miR-146a/b are up-regulated in human atherosclerotic plaques in the Tampere Vascular Study
Emma Raitoharju et al.
ATHEROSCLEROSIS (2011)
MicroRNA signatures in total peripheral blood as novel biomarkers for acute myocardial infarction
Benjamin Meder et al.
BASIC RESEARCH IN CARDIOLOGY (2011)
Involvement of miR-30c and miR-301a in immediate induction of plasminogen activator inhibitor-1 by placental growth factor in human pulmonary endothelial cells
Nitin Patel et al.
BIOCHEMICAL JOURNAL (2011)
Selective depletion of plasma prekallikrein or coagulation factor XII inhibits thrombosis in mice without increased risk of bleeding
Alexey S. Revenko et al.
BLOOD (2011)
Assessment of Plasma miRNAs in Congestive Heart Failure
Yasue Fukushima et al.
CIRCULATION JOURNAL (2011)
Induction of miR-21 by Retinoic Acid in Estrogen Receptor-positive Breast Carcinoma Cells BIOLOGICAL CORRELATES AND MOLECULAR TARGETS
Mineko Terao et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
MicroRNA-19 (miR-19) Regulates Tissue Factor Expression in Breast Cancer Cells
Xiaoxi Zhang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
MicroRNA-18a Enhances the Interleukin-6-mediated Production of the Acute-phase Proteins Fibrinogen and Haptoglobin in Human Hepatocytes
Matthias Brock et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
Identification of miRNAs as potential modulators of tissue factor expression in patients with systemic lupus erythematosus and antiphospholipid syndrome
R. Teruel et al.
JOURNAL OF THROMBOSIS AND HAEMOSTASIS (2011)
MicroRNA-134 as a potential plasma biomarker for the diagnosis of acute pulmonary embolism
Junjie Xiao et al.
JOURNAL OF TRANSLATIONAL MEDICINE (2011)
p38 MAPK Controls Prothrombin Expression by Regulated RNA 3′ End Processing
Sven Danckwardt et al.
MOLECULAR CELL (2011)
MicroRNAs can generate thresholds in target gene expression
Shankar Mukherji et al.
NATURE GENETICS (2011)
Gene silencing by microRNAs: contributions of translational repression and mRNA decay
Eric Huntzinger et al.
NATURE REVIEWS GENETICS (2011)
MECHANISMS OF DISEASE The Hemostatic System as a Modulator of Atherosclerosis
Julian Ilcheff Borissoff et al.
NEW ENGLAND JOURNAL OF MEDICINE (2011)
Apixaban versus Warfarin in Patients with Atrial Fibrillation
Christopher B. Granger et al.
NEW ENGLAND JOURNAL OF MEDICINE (2011)
Rivaroxaban versus Warfarin in Nonvalvular Atrial Fibrillation
Manesh R. Patel et al.
NEW ENGLAND JOURNAL OF MEDICINE (2011)
Synergistic Post-Transcriptional Regulation of the Cystic Fibrosis Transmembrane conductance Regulator (CFTR) by miR-101 and miR-494 Specific Binding
Francesca Megiorni et al.
PLOS ONE (2011)
Subcellular Fate and Off-Target Effects of siRNA, shRNA, and miRNA
Saurabh Singh et al.
PHARMACEUTICAL RESEARCH (2011)
Patients with severe factor XI deficiency have a reduced incidence of deep-vein thrombosis
Ophira Salomon et al.
THROMBOSIS AND HAEMOSTASIS (2011)
Continuing Education Course #2: Current Understanding of Hemostasis
Andrew J. Gale
TOXICOLOGIC PATHOLOGY (2011)
Regulation of mRNA Translation and Stability by microRNAs
Marc Robert Fabian et al.
ANNUAL REVIEW OF BIOCHEMISTRY, VOL 79 (2010)
Inhibition of the intrinsic coagulation pathway factor XI by antisense oligonucleotides: a novel antithrombotic strategy with lowered bleeding risk
Hong Zhang et al.
BLOOD (2010)
Regulation of fibrinogen production by microRNAs
Alexandre Fort et al.
BLOOD (2010)
MiR423-5p As a Circulating Biomarker for Heart Failure
Anke J. Tijsen et al.
CIRCULATION RESEARCH (2010)
Circulating MicroRNAs in Patients With Coronary Artery Disease
Stephan Fichtlscherer et al.
CIRCULATION RESEARCH (2010)
Susceptibility to chronic thromboembolic pulmonary hypertension may be conferred by miR-759 via its targeted interaction with polymorphic fibrinogen alpha gene
Zhiyong Chen et al.
HUMAN GENETICS (2010)
The widespread regulation of microRNA biogenesis, function and decay
Jacek Krol et al.
NATURE REVIEWS GENETICS (2010)
Oral Rivaroxaban for Symptomatic Venous Thromboembolism.
Rupert Bauersachs et al.
NEW ENGLAND JOURNAL OF MEDICINE (2010)
Therapeutic Silencing of MicroRNA-122 in Primates with Chronic Hepatitis C Virus Infection
Robert E. Lanford et al.
SCIENCE (2010)
Newer antithrombotic drugs
Pranav Sikka et al.
INDIAN JOURNAL OF CRITICAL CARE MEDICINE (2010)
Prevention of vascular graft occlusion and thrombus-associated thrombin generation by inhibition of factor XI
Erik I. Tucker et al.
BLOOD (2009)
Dual role of collagen in factor XII-dependent thrombus formation
Paola E. J. van der Meijden et al.
BLOOD (2009)
Platelet Polyphosphates Are Proinflammatory and Procoagulant Mediators In Vivo
Felicitas Muller et al.
CELL (2009)
MicroRNAs: Target Recognition and Regulatory Functions
David P. Bartel
CELL (2009)
The knockout of miR-143 and-145 alters smooth muscle cell maintenance and vascular homeostasis in mice: correlates with human disease
L. Ella et al.
CELL DEATH AND DIFFERENTIATION (2009)
RNAi-based therapeutics-current status, challenges and prospects
Katrin Tiemann et al.
EMBO MOLECULAR MEDICINE (2009)
Controlled delivery of antisense oligonucleotides: a brief review of current strategies
Xiubo Zhao et al.
EXPERT OPINION ON DRUG DELIVERY (2009)
Most mammalian mRNAs are conserved targets of microRNAs
Robin C. Friedman et al.
GENOME RESEARCH (2009)
miR-145 and miR-143 regulate smooth muscle cell fate and plasticity
Kimberly R. Cordes et al.
NATURE (2009)
Dabigatran versus Warfarin in Patients with Atrial Fibrillation.
Stuart J. Connolly et al.
NEW ENGLAND JOURNAL OF MEDICINE (2009)
Reduced incidence of ischemic stroke in patients with severe factor XI deficiency
Ophira Salomon et al.
BLOOD (2008)
3′ end mRNA processing:: molecular mechanisms and implications for health and disease
Sven Danckwardt et al.
EMBO JOURNAL (2008)
Widespread changes in protein synthesis induced by microRNAs
Matthias Selbach et al.
NATURE (2008)
LNA-mediated microRNA silencing in non-human primates
Joacim Elmen et al.
NATURE (2008)
Determinants of targeting by endogenous and exogenous microRNAs and siRNAs
Cydney B. Nielsen et al.
RNA (2007)
MicroRNA targeting specificity in mammals: Determinants beyond seed pairing
Andrew Grimson et al.
MOLECULAR CELL (2007)
The evolution of gene regulation by transcription factors and microRNAs
Kevin Chen et al.
NATURE REVIEWS GENETICS (2007)
Levels of intrinsic coagulation factors and the risk of myocardial infarction among men: opposite and synergistic effects of factors XI and YII
Carine J. M. Doggen et al.
BLOOD (2006)
Elevated factor XI activity levels are associated with an increased odds ratio for cerebrovascular events
David T. Yang et al.
AMERICAN JOURNAL OF CLINICAL PATHOLOGY (2006)
Designing siRNA that distinguish between genes that differ by a single nucleotide
Dianne S. Schwarz et al.
PLOS GENETICS (2006)
Cell type-specific delivery of siRNAs with aptamer-siRNA chimeras
James O. McNamara et al.
NATURE BIOTECHNOLOGY (2006)
Antisense oligonucleotides: From design to therapeutic application
JHP Chan et al.
CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY (2006)
Cell-type-specific signatures of microRNAs on target mRNA expression
P Sood et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
Silencing of microRNAs in vivo with 'antagomirs'
J Krützfeldt et al.
NATURE (2005)
Defective thrombus formation in mice lacking coagulation factor XII
T Renné et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2005)
Antibody mediated in vivo delivery of small interfering RNAs via cell-surface receptors
EW Song et al.
NATURE BIOTECHNOLOGY (2005)
Effects of factor IX or factor XI deficiency on ferric chloride-induced carotid artery occlusion in mice
X Wang et al.
JOURNAL OF THROMBOSIS AND HAEMOSTASIS (2005)
Genetic determinants of arterial thrombosis
B Voetsch et al.
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2004)
Kinetic analysis of the RNAi enzyme complex
B Haley et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2004)
Many commonly used siRNAs risk off-target activity
O Snove et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2004)
RISC is a 5′ phosphomonoester-producing RNA endonuclease
J Martinez et al.
GENES & DEVELOPMENT (2004)
Clinical impact of bleeding in patients taking oral anticoagulant therapy for venous thromboembolism - A meta-analysis
LA Linkins et al.
ANNALS OF INTERNAL MEDICINE (2003)
Inter-relation of coagulation factors and D-dimer levels in healthy individuals
AV Vlieg et al.
JOURNAL OF THROMBOSIS AND HAEMOSTASIS (2003)
Regulation of PAI-1 concentration in platelets by systemic administration of antisense oligonucleotides to rats
Z Pawlowska et al.
THROMBOSIS AND HAEMOSTASIS (2001)
Activation of clotting factors XI and IX in patients with acute myocardial infarction
MC Minnema et al.
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2000)
High levels of coagulation factor XI as a risk factor for venous thrombosis.
JCM Meijers et al.
NEW ENGLAND JOURNAL OF MEDICINE (2000)