Related references
Note: Only part of the references are listed.Association of TNFSF4 Gene Polymorphisms and Plasma TNFSF4 Level with Risk of Systemic Lupus Erythematosus in a Chinese Population
Lu-Yao Yue et al.
IMMUNOLOGICAL INVESTIGATIONS (2022)
Nutraceutical nanodelivery; an insight into the bioaccessibility/bioavailability of different bioactive compounds loaded within nanocarriers
Cristian Dima et al.
CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION (2021)
CD40 Agonist Antibodies in Cancer Immunotherapy
Robert H. Vonderheide
ANNUAL REVIEW OF MEDICINE, VOL 71, 2020 (2020)
Tumor-expressed B7-H3 mediates the inhibition of antitumor T-cell functions in ovarian cancer insensitive to PD-1 blockade therapy
Dongli Cai et al.
CELLULAR & MOLECULAR IMMUNOLOGY (2020)
Distinct anterograde trafficking pathways of BACE1 and amyloid precursor protein from the TGN and the regulation of amyloid-β production
Jing Zhi A. Tan et al.
MOLECULAR BIOLOGY OF THE CELL (2020)
NME2 Is a Master Suppressor of Apoptosis in Gastric Cancer Cells via Transcriptional Regulation of miR-100 and Other Survival Factors
Yi Gong et al.
MOLECULAR CANCER RESEARCH (2020)
Adaptive immunity: an emerging player in the progression of NAFLD
Salvatore Sutti et al.
NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY (2020)
VCAM-1 secreted from cancer-associated fibroblasts enhances the growth and invasion of lung cancer cells through AKT and MAPK signaling
Zhuan Zhou et al.
CANCER LETTERS (2020)
Heightened systemic levels of anti-inflammatory cytokines in pulmonary tuberculosis and alterations following anti-tuberculosis treatment
Kadar Moideen et al.
CYTOKINE (2020)
Automobile exhaust-derived PM2.5 induces blood-testis barrier damage through ROS-MAPK-Nrf2 pathway in sertoli cells of rats
Bin Liu et al.
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY (2020)
Mitochondrial residence of the apoptosis inducer BAX is more important than BAX oligomerization in promoting membrane permeabilization
Tomomi Kuwana et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2020)
CD70 expression correlates with a worse prognosis in malignant pleural mesothelioma patients via immune evasion and enhanced invasiveness
Shingo Inaguma et al.
JOURNAL OF PATHOLOGY (2020)
Protein kinase 2 (CK2) controls CD4+ T cell effector function in the pathogenesis of colitis
Wei Yang et al.
MUCOSAL IMMUNOLOGY (2020)
The apatinib inhibits breast cancer cell line MDA-MB-231 in vitro by inducing apoptosis, cell cycle arrest, and regulating nuclear factor-κB (NF-κB) and mitogen-activated protein kinase (MAPK) signaling pathways
Nazila Fathi Maroufi et al.
BREAST CANCER (2020)
Epigenetic conversion of conventional T cells into regulatory T cells by CD28 signal deprivation
Norihisa Mikami et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2020)
Mixed lineage kinase 3 inhibition induces T cell activation and cytotoxicity
Sandeep Kumar et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2020)
Toxoplasma gondii dense granule protein GRA24 drives MyD88-independent p38 MAPK activation, IL-12 production and induction of protective immunity
Heather L. Mercer et al.
PLoS Pathogens (2020)
Small molecules, big impact: 20 years of targeted therapy in oncology
Philippe L Bedard et al.
LANCET (2020)
Dual Relief of T-lymphocyte Proliferation and Effector Function Underlies Response to PD-1 Blockade in Epithelial Malignancies
Camille-Charlotte Balanca et al.
CANCER IMMUNOLOGY RESEARCH (2020)
m6A regulator-mediated methylation modification patterns and tumor microenvironment infiltration characterization in gastric cancer
Bo Zhang et al.
MOLECULAR CANCER (2020)
Blockade of CD40L inhibits immunogenic maturation of lung dendritic cells: Implications for the role of lung iNKT cells in mouse models of asthma
Nishan Deng et al.
MOLECULAR IMMUNOLOGY (2020)
Rationalized inhibition of mixed lineage kinase 3 and CD70 enhances life span and antitumor efficacy of CD8+T cells
Sandeep Kumar et al.
JOURNAL FOR IMMUNOTHERAPY OF CANCER (2020)
Dysfunction of pulmonary epithelial tight junction induced by silicon dioxide nanoparticles via the ROS/ERK pathway and protein degradation
Yingqi Liu et al.
CHEMOSPHERE (2020)
Tumor-targeted CD28 bispecific antibodies enhance the antitumor efficacy of PD-1 immunotherapy
Janelle C. Waite et al.
SCIENCE TRANSLATIONAL MEDICINE (2020)
Molecular characterization and expression analysis of chemokine (CXCL12) from Nile tilapia (Oreochromis niloticus)
Along Gao et al.
FISH & SHELLFISH IMMUNOLOGY (2020)
Regulation of the innate immune system by autophagy: monocytes, macrophages, dendritic cells and antigen presentation
Nina Germic et al.
CELL DEATH AND DIFFERENTIATION (2019)
Reactive oxygen species modulate macrophage immunosuppressive phenotype through the up-regulation of PD-L1
Cecilia Roux et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2019)
Advanced assessment of migration and invasion of cancer cells in response to mifepristone therapy using double fluorescence cytochemical labeling
Sabrina J. Ritch et al.
BMC CANCER (2019)
Indoxyl sulfate induces myotube atrophy by ROS-ERK and JNK-MAFbx cascades
Chih-Ying Changchien et al.
CHEMICO-BIOLOGICAL INTERACTIONS (2019)
ADP heptose, a novel pathogen-associated molecular pattern identified in Helicobacter pylori
Lennart Pfannkuch et al.
FASEB JOURNAL (2019)
MLK3 silence induces cervical cancer cell apoptosis via the Notch-1/autophagy network
Liya Ma et al.
CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY (2019)
High-Throughput Screening Identifies Mixed-Lineage Kinase 3 as a Key Host Regulatory Factor in Zika Virus Infection
Hua Xu et al.
JOURNAL OF VIROLOGY (2019)
The TNF Paradox in Cancer Progression and Immunotherapy
Anne Montfort et al.
FRONTIERS IN IMMUNOLOGY (2019)
Efficient apoptosis requires feedback amplification of upstream apoptotic signals by effector caspase-3 or -7
Scott McComb et al.
SCIENCE ADVANCES (2019)
Decrease of MLK4 prevents hepatocellular carcinoma (HCC) through reducing metastasis and inducing apoptosis regulated by ROS/MAPKs signaling
Yu Li et al.
BIOMEDICINE & PHARMACOTHERAPY (2019)
The second generation mixed lineage kinase-3 (MLK3) inhibitor CLFB-1134 protects against neurotoxin-induced nigral dopaminergic neuron loss
Elizabeth M. Kline et al.
EXPERIMENTAL NEUROLOGY (2019)
Mixed lineage kinase-3 prevents cardiac dysfunction and structural remodeling with pressure overload
Timothy D. Calamaras et al.
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2019)
Tumour cell-intrinsic CTLA4 regulates PD-L1 expression in non-small cell lung cancer
Huijun Zhang et al.
JOURNAL OF CELLULAR AND MOLECULAR MEDICINE (2019)
Mixed lineage kinase 3 promotes breast tumorigenesis via phosphorylation and activation of p21-activated kinase 1
Subhasis Das et al.
ONCOGENE (2019)
Upregulation of MLK4 promotes migratory and invasive potential of breast cancer cells
Anna A. Marusiak et al.
ONCOGENE (2019)
IQGAP-related protein IqgC suppresses Ras signaling during large-scale endocytosis
Maja Marinovic et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2019)
Can spectral computed tomography imaging improve the differentiation between malignant and benign pulmonary lesions manifesting as solitary pure ground glass, mixed ground glass, and solid nodules?
Mai-Lin Chen et al.
THORACIC CANCER (2019)
IRE1α Activation in Bone Marrow-Derived Dendritic Cells Modulates Innate Recognition of Melanoma Cells and Favors CD8+ T Cell Priming
Bernardita Medel et al.
FRONTIERS IN IMMUNOLOGY (2019)
New emerging targets in cancer immunotherapy: the role of Cluster of Differentiation 40 (CD40/TNFR5)
Manuel Piechutta et al.
ESMO OPEN (2019)
Attributable Failure of First-line Cancer Treatment and Incremental Costs Associated With Smoking by Patients With Cancer
Graham W. Warren et al.
JAMA NETWORK OPEN (2019)
Peptidyl prolyl cis/trans isomerase activity on the cell surface correlates with extracellular matrix development
Weilin Lin et al.
COMMUNICATIONS BIOLOGY (2019)
Knockout of mitochondrial voltage-dependent anion channel type 3 increases reactive oxygen species (ROS) levels and alters renal sodium transport
Li Zou et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2018)
MLK3 phosphorylation by ERK1/2 is required for oxidative stress-induced invasion of colorectal cancer cells
A. L. Schroyer et al.
ONCOGENE (2018)
Plasticity of Human THP-1 Cell Phagocytic Activity during Macrophagic Differentiation
A. V. Kurynina et al.
BIOCHEMISTRY-MOSCOW (2018)
Microenvironment-induced CD44v6 promotes early disease progression in chronic lymphocytic leukemia
Julia C. Gutjahr et al.
BLOOD (2018)
URMC-099 facilitates amyloid-β clearance in a murine model of Alzheimer's disease
Tomomi Kiyota et al.
JOURNAL OF NEUROINFLAMMATION (2018)
Kinase-targeted cancer therapies: progress, challenges and future directions
Khushwant S. Bhullar et al.
MOLECULAR CANCER (2018)
G Protein-Coupled Receptors as Targets for Approved Drugs: How Many Targets and How Many Drugs?
Krishna Sriram et al.
MOLECULAR PHARMACOLOGY (2018)
Rapid purification of billions of circulating CD19+B cells directly from leukophoresis samples
Fortunato Ferrara et al.
NEW BIOTECHNOLOGY (2018)
Breast cancer stem cells characterized by CD70 expression preferentially metastasize to the lungs
Li Liu et al.
BREAST CANCER (2018)
Unveiling a CD70-positive subset of cancer-associated fibroblasts marked by pro-migratory activity and thriving regulatory T cell accumulation
Julie Jacobs et al.
ONCOIMMUNOLOGY (2018)
A Small-molecule Kinase Inhibitor, CEP-1347, Inhibits Survivin Expression and Sensitizes Ovarian Cancer Stem Cells to Paclitaxel
Keita Togashi et al.
ANTICANCER RESEARCH (2018)
Actin Cytoskeleton Remodeling Drives Breast Cancer Cell Escape from Natural Killer-Mediated Cytotoxicity
Antoun Al Absi et al.
CANCER RESEARCH (2018)
The Role of Toll-Like Receptors in the Production of Cytokines by Human Lung Macrophages
Stanislas Grassin-Delyle et al.
Journal of Innate Immunity (2018)
Protein kinase p38α signaling in dendritic cells regulates colon inflammation and tumorigenesis
Tingting Zheng et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2018)
IFN-gamma-inducible antiviral responses require ULK1-mediated activation of MLK3 and ERK5
Diana Saleiro et al.
SCIENCE SIGNALING (2018)
PIN1 in Cell Cycle Control and Cancer
Chi-Wai Cheng et al.
FRONTIERS IN PHARMACOLOGY (2018)
The Mixed-Lineage Kinase Inhibitor URMC-099 Protects Hippocampal Synapses in Experimental Autoimmune Encephalomyelitis
Matthew J. Bellizzi et al.
ENEURO (2018)
Chemoresistance of Cancer Cells: Requirements of Tumor Microenvironment-mimicking In Vitro Models in Anti-Cancer Drug Development
Yeonho Jo et al.
THERANOSTICS (2018)
Mixed Lineage Kinase 3 Mediates the Induction of CXCL10 by a STAT1-Dependent Mechanism During Hepatocyte Lipotoxicity
Kyoko Tomita et al.
JOURNAL OF CELLULAR BIOCHEMISTRY (2017)
Heme Oxygenase-1 Inhibits Neuronal Apoptosis in Spinal Cord Injury through Down-Regulation of Cdc42-MLK3-MKK7-JNK3 Axis
Wenping Lin et al.
JOURNAL OF NEUROTRAUMA (2017)
EGFR Signals through a DOCK180-MLK3 Axis to Drive Glioblastoma Cell Invasion
Sean A. Misek et al.
MOLECULAR CANCER RESEARCH (2017)
PAK signalling drives acquired drug resistance to MAPK inhibitors in BRAF-mutant melanomas
Hezhe Lu et al.
NATURE (2017)
NFATc1 controls the cytotoxicity of CD8+ T cells
Stefan Klein-Hessling et al.
NATURE COMMUNICATIONS (2017)
Repositioning CEP-1347, a chemical agent originally developed for the treatment of Parkinson's disease, as an anti-cancer stem cell drug
Masashi Okada et al.
ONCOTARGET (2017)
Transcriptional regulation of mixed lineage kinase 3 by estrogen and its implication in ER-positive breast cancer pathogenesis
Navin Viswakarma et al.
ONCOTARGET (2017)
A MIG-15/JNK-1 MAP kinase cascade opposes RPM-1 signaling in synapse formation and learning
Oliver Crawley et al.
PLOS GENETICS (2017)
MLK3 regulates FRA-1 and MMPs to drive invasion and transendothelial migration in triple-negative breast cancer cells
C. Rattanasinchai et al.
ONCOGENESIS (2017)
Neutrophil evolution and Their Diseases in Humans
Jennifer W. Leiding
FRONTIERS IN IMMUNOLOGY (2017)
Intermediate Filaments at the Junction of Mechanotransduction, Migration, and Development
Rucha Sanghvi-Shah et al.
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY (2017)
The development of T cells from stem cells in mice and humans
Farbod Famili et al.
FUTURE SCIENCE OA (2017)
Phase I Dose-Escalation Study of the Anti-CD70 Antibody ARGX-110 in Advanced Malignancies
Philippe Aftimos et al.
CLINICAL CANCER RESEARCH (2017)
The Different Mechanisms of Cancer Drug Resistance: A Brief Review
Behzad Mansoori et al.
ADVANCED PHARMACEUTICAL BULLETIN (2017)
Mixed-lineage kinase 3 pharmacological inhibition attenuates murine nonalcoholic steatohepatitis
Kyoko Tomita et al.
JCI INSIGHT (2017)
Targeted Therapy in Thyroid Cancer: State of the Art
L. Valerio et al.
CLINICAL ONCOLOGY (2017)
Prospects for combining targeted and conventional cancer therapy with immunotherapy
Philip Gotwals et al.
NATURE REVIEWS CANCER (2017)
Factors associated with failure of oncology drugs in late-stage clinical development: A systematic review
Denis L. Jardim et al.
CANCER TREATMENT REVIEWS (2017)
MAP3K11 is a tumor suppressor targeted by the oncomiR miR-125b in early B cells
U. Knackmuss et al.
CELL DEATH AND DIFFERENTIATION (2016)
Role of Merlin/NF2 inactivation in tumor biology
A. M. Petrilli et al.
ONCOGENE (2016)
Overexpression of miR-199a-5p decreases esophageal cancer cell proliferation through repression of mitogen-activated protein kinase kinase kinase-11 (MAP3K11)
Kimberly A. Byrnes et al.
ONCOTARGET (2016)
Serine/Threonine Kinase MLK4 Determines Mesenchymal Identity in Glioma Stem Cells in an NF-κB-dependent Manner
Sung-Hak Kim et al.
CANCER CELL (2016)
CD28 Costimulation: From Mechanism to Therapy
Jonathan H. Esensten et al.
IMMUNITY (2016)
The mixed-lineage kinase 3 inhibitor URMC-099 facilitates microglial amyloid-β degradation
Weiguo Dong et al.
JOURNAL OF NEUROINFLAMMATION (2016)
Neutrophils Suppress Intraluminal NK Cell-Mediated Tumor Cell Clearance and Enhance Extravasation of Disseminated Carcinoma Cells
Asaf Spiegel et al.
CANCER DISCOVERY (2016)
Expression of the immune regulation antigen CD70 in osteosarcoma
Jens H. W. Pahl et al.
CANCER CELL INTERNATIONAL (2015)
Atomic structure of the apoptosome: mechanism of cytochrome c- and dATP-mediated activation of Apaf-1
Mengying Zhou et al.
GENES & DEVELOPMENT (2015)
Human Epidermal Growth Factor Receptor 2 (HER2) Impedes MLK3 Kinase Activity to Support Breast Cancer Cell Survival
Subhasis Das et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2015)
TRAIL receptor deletion in mice suppresses the inflammation of nutrient excess
Leila Idrissova et al.
JOURNAL OF HEPATOLOGY (2015)
CD70: An emerging target in cancer immunotherapy
J. Jacobs et al.
PHARMACOLOGY & THERAPEUTICS (2015)
The Neuroglial Potassium Cycle during Neurotransmission: Role of Kir4.1 Channels
Jeremie Sibille et al.
PLOS COMPUTATIONAL BIOLOGY (2015)
MLK3 promotes melanoma proliferation and invasion and is a target of microRNA-125b
J. Zhang et al.
CLINICAL AND EXPERIMENTAL DERMATOLOGY (2014)
Scaffold State Switching Amplifies, Accelerates, and Insulates Protein Kinase C Signaling
Eric C. Greenwald et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2014)
MLK3 regulates fMLP-stimulated neutrophil motility
Oksana Polesskaya et al.
MOLECULAR IMMUNOLOGY (2014)
MLK3 Is Part of a Feedback Mechanism That Regulates Different Cellular Responses to Reactive Oxygen Species
Ho-Sung Lee et al.
SCIENCE SIGNALING (2014)
Different Inward and Outward Conduction Mechanisms in NaVMs Suggested by Molecular Dynamics Simulations
Song Ke et al.
PLOS COMPUTATIONAL BIOLOGY (2014)
Hepatitis C Virus NS5A Inhibits Mixed Lineage Kinase 3 to Block Apoptosis
Yutaka Amako et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2013)
Discovery, Synthesis, and Characterization of an Orally Bioavailable, Brain Penetrant Inhibitor of Mixed Lineage Kinase
Val S. Goodfellow et al.
JOURNAL OF MEDICINAL CHEMISTRY (2013)
The New Small-Molecule Mixed-Lineage Kinase 3 Inhibitor URMC-099 Is Neuroprotective and Anti-Inflammatory in Models of Human Immunodeficiency Virus-Associated Neurocognitive Disorders
Daniel F. Marker et al.
JOURNAL OF NEUROSCIENCE (2013)
Innate and adaptive immune cells in the tumor microenvironment
Thomas F. Gajewski et al.
NATURE IMMUNOLOGY (2013)
Mitochondrial Regulation of Cell Death
Stephen W. G. Tait et al.
COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY (2013)
The role of TRADD in death receptor signaling
Yelena L. Pobezinskaya et al.
CELL CYCLE (2012)
MLK4 has negative effect on TLR4 signaling
Alim Seit-Nebi et al.
CELLULAR & MOLECULAR IMMUNOLOGY (2012)
Mixed lineage kinase 3 is required for matrix metalloproteinase expression and invasion in ovarian cancer cells
Yu Zhan et al.
EXPERIMENTAL CELL RESEARCH (2012)
Kidney-infiltrating CD4+ T-cell clones promote nephritis in lupus-prone mice
Akiko Okamoto et al.
KIDNEY INTERNATIONAL (2012)
Mixed-lineage kinase 3 phosphorylates prolyl-isomerase Pin1 to regulate its nuclear translocation and cellular function
Velusamy Rangasamy et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
ACS Chemical Neuroscience Spotlight on CEP-1347
Zachary K. Sweeney et al.
ACS CHEMICAL NEUROSCIENCE (2011)
Hematopoietic progenitor migration to the adult thymus
Daniel A. Zlotoff et al.
YEAR IN IMMUNOLOGY (2011)
MicroRNA-34a is a potent tumor suppressor molecule in vivo in neuroblastoma
Amanda Tivnan et al.
BMC CANCER (2011)
Regulation of mixed lineage kinase 3 is required for Neurofibromatosis-2-mediated growth suppression in human cancer
Y. Zhan et al.
ONCOGENE (2011)
Estrogen Suppresses MLK3-Mediated Apoptosis Sensitivity in ER+ Breast Cancer Cells
Velusamy Rangasamy et al.
CANCER RESEARCH (2010)
Tumor Necrosis Factor-a Signaling in Macrophages
Narayanan Parameswaran et al.
CRITICAL REVIEWS IN EUKARYOTIC GENE EXPRESSION (2010)
Mixed lineage kinase 3 gene mutations in mismatch repair deficient gastrointestinal tumours
Sergia Velho et al.
HUMAN MOLECULAR GENETICS (2010)
Mixed Lineage Kinase-3 Stabilizes and Functionally Cooperates with TRIBBLES-3 to Compromise Mitochondrial Integrity in Cytokine-induced Death of Pancreatic Beta Cells
Rohan K. Humphrey et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
Dyad of CD40/CD40 Ligand Fosters Neuroinflammation at the Blood-Brain Barrier and Is Regulated via JNK Signaling: Implications for HIV-1 Encephalitis
Servio H. Ramirez et al.
JOURNAL OF NEUROSCIENCE (2010)
Mixed Lineage Kinase-3/JNK1 Axis Promotes Migration of Human Gastric Cancer Cells following Gastrin Stimulation
Prajna Mishra et al.
MOLECULAR ENDOCRINOLOGY (2010)
MLK3 is critical for breast cancer cell migration and promotes a malignant phenotype in mammary epithelial cells
J. Chen et al.
ONCOGENE (2010)
Mixed lineage kinase 3 negatively regulates IKK activity and enhances etoposide-induced cell death
Eric T. Cole et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2009)
Cytokine-induced activation of mixed lineage kinase 3 requires TRAF2 and TRAF6
Amanda C. Korchnak et al.
CELLULAR SIGNALLING (2009)
Mixed Lineage Kinase Phosphorylates Transcription Factor E47 and Inhibits TrkB Expression to Link Neuronal Death and Survival Pathways
Neus Pedraza et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
Mixed lineage kinase 2 and hippocalcin are localized in Lewy bodies of Parkinson's disease
Masahiro Nagao et al.
JOURNAL OF THE NEUROLOGICAL SCIENCES (2009)
Suppression of a pro-apoptotic K+ channel as a mechanism for hepatitis C virus persistence
Jamel Mankouri et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
Mixed-lineage kinase 1 and mixed-lineage kinase 3 subtype-selective dihydronaphthyl[3,4-a]pyrrolo[3,4-c]carbazole-5-ones: Optimization, mixed-lineage kinase 1 crystallography, and oral in vivo activity in 1-methyl-4-phenyltetrahydropyridine models
Robert L. Hudkins et al.
JOURNAL OF MEDICINAL CHEMISTRY (2008)
Mixed lineage kinase 3 connects reactive oxygen species to c-Jun NH2-terminal kinase-induced mitochondrial apoptosis in genipin-treated PC3 human prostate cancer cells
Hye-Young Hong et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2007)
Glycogen synthase kinase-3β induces neuronal cell death via direct phosphorylation of mixed lineage kinase 3
Rajakishore Mishra et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
Mixed lineage kinase inhibitor CEP-1347 fails to delay disability in early Parkinson disease
Ira Shoulson et al.
NEUROLOGY (2007)
Dissection of a signaling pathway by which pathogen-associated molecular patterns recruit the JNK and p38 MAPKs and trigger cytokine release
Jian Zhong et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
Expression and function of mixed lineage kinases in dendritic cells
Matthew E. Handley et al.
INTERNATIONAL IMMUNOLOGY (2007)
Inhibition of mixed lineage kinase 3 prevents HIV-1 Tat-mediated neurotoxicity and monocyte activation
Ziye Sui et al.
JOURNAL OF IMMUNOLOGY (2006)
Chemokines enhance immunity by guiding naive CD8+ T cells to sites of CD4 T cell-dendritic cell interaction
F Castellino et al.
NATURE (2006)
MyD88-mediated stabilization of interferon-γ-induced cytokine and chemokine mRNA
DX Sun et al.
NATURE IMMUNOLOGY (2006)
Potential crosstalk between insulin-like growth factor receptor type 1 and epidermal growth factor receptor in progression and metastasis of pancreatic cancer
Shigeto Ueda et al.
MODERN PATHOLOGY (2006)
Cdc42 induces activation loop phosphorylation and membrane targeting of mixed lineage kinase 3
Y Du et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Regulation of apoptotic c-Jun N-terminal kinase signaling by a stabilization-based feed-forward loop
ZH Xu et al.
MOLECULAR AND CELLULAR BIOLOGY (2005)
Cyclophilin A-deficient mice are resistant to immunosuppression by cyclosporine
J Colgan et al.
JOURNAL OF IMMUNOLOGY (2005)
Role of MLK3 in the regulation of mitogen-activated protein kinase signaling cascades
D Brancho et al.
MOLECULAR AND CELLULAR BIOLOGY (2005)
A novel role for mixed lineage kinase 3 (MLK3) in B-Raf activation and cell proliferation
DN Chadee et al.
CELL CYCLE (2004)
Thymic T cell development and progenitor localization depend on CCR7
A Misslitz et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2004)
Gonadotropin-releasing hormone induces apoptosis of prostate cancer cells:: Role of c-Jun NH2-terminal kinase, protein kinase B, and extracellular signal-regulated kinase pathways
S Kraus et al.
CANCER RESEARCH (2004)
Phosphoregulation of mixed-lineage kinase 1 activity by multiple phosphorylation in the activation loop
JT Durkin et al.
BIOCHEMISTRY (2004)
Cyclophilin A regulates TCR signal strength in CD4+ T cells via a proline-directed conformational switch in Itk
J Colgan et al.
IMMUNITY (2004)
MLK3 is required for mitogen activation of B-Raf, ERK and cell proliferation
DN Chadee et al.
NATURE CELL BIOLOGY (2004)
Paraquat induces oxidative stress and neuronal cell death;: neuroprotection by water-soluble Coenzyme Q10
S McCarthy et al.
TOXICOLOGY AND APPLIED PHARMACOLOGY (2004)
CEP11004, a novel inhibitor of the mixed lineage kinases, suppresses apoptotic death in dopamine neurons of the substantia nigra induced by 6-hydroxydopamine
A Ganguly et al.
JOURNAL OF NEUROCHEMISTRY (2004)
Hsp90/p50cdc37 is required for mixed-lineage kinase (MLK) 3 signaling
H Zhang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Mutational analysis of the tyrosine kinome in colorectal cancers
A Bardelli et al.
SCIENCE (2003)
The JNK-interacting protein-1 scaffold protein targets MAPK phosphatase-7 to dephosphorylate JNK
EA Willoughby et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
A new identity for MLK3 as an NIMA-related, cell cycle-regulated kinase that is localized near centrosomes and influences microtubule organization
KI Swenson et al.
MOLECULAR BIOLOGY OF THE CELL (2003)
Activation of the Drosophila MLK by ceramide reveals TNF-α and ceramide as agonists of mammalian MLK3
P Sathyanarayana et al.
MOLECULAR CELL (2002)
Mixed lineage kinase 3 mediates gp120IIIB-induced neurotoxicity
A Bodner et al.
JOURNAL OF NEUROCHEMISTRY (2002)
Ara-C- and daunorubicin-induced recruitment of Lyn in sphingomyelinase-enriched membrane rafts
S Grazide et al.
FASEB JOURNAL (2002)
Dysregulation of apoptosis genes in hematopoietic malignancies
S Kitada et al.
ONCOGENE (2002)
Bax and Bak promote apoptosis by modulating endoplasmic reticular and mitochondrial Ca2+ stores
LK Nutt et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Mitogen-activated protein kinase kinase 7 is activated during low potassium-induced apoptosis in rat cerebellar granule neurons
L Trotter et al.
NEUROSCIENCE LETTERS (2002)
Evidence for a role of mixed lineage kinases in neuronal apoptosis
M Mota et al.
JOURNAL OF NEUROSCIENCE (2001)
CEP-1347 (KT7515), a semisynthetic inhibitor of the mixed lineage kinase family
AC Maroney et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
The MLK family mediates c-Jun N-terminal kinase activation in neuronal apoptosis
ZH Xu et al.
MOLECULAR AND CELLULAR BIOLOGY (2001)
The kinase activation loop is the key to mixed lineage kinase-3 activation via both autophosphorylation and hematopoetic progenitor kinase 1 phosphorylation
IWL Leung et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Cdc42-induced activation of the mixed-lineage kinase SPRK in vivo -: Requirement of the Cdc42/Rac interactive binding motif and changes in phosphorylation
BC Böck et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
Share Paper
