4.5 Article

Follow-up Study of Long-time Positive RT-PCR in Stool Specimens From Asymptomatic Children Infected With SARS-CoV-2

Journal

PEDIATRIC INFECTIOUS DISEASE JOURNAL
Volume 39, Issue 10, Pages E315-E317

Publisher

LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.1097/INF.0000000000002837

Keywords

SARS-CoV-2; reverse transcription-polymerase chain reaction; children; asymptomatic; stool specimens

Funding

  1. National Clinical Research Center for Child Health and Disorders (Children's Hospital of Chongqing Medical University, Chongqing, China) [NCRCCHD-2020-EP-01]
  2. fourth batch of Special Project of Science and Technology for Emergency Response to COVID-19 of Chongqing Science and Technology Bureau

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In the current study, we report on 4 children with confirmed SARS-CoV-2 infection, of which 3 of them were asymptomatic. These patients had both pharyngeal swabs and anal swabs testing during hospital or after discharge. All the 4 children showed long-time positive viral RNA in the stool specimens after pharyngeal swabs turned negative during the follow-up stage, especially in the asymptomatic children. The positive RNA in stool specimens of asymptomatic children last for more than 54 days after admission or 30 days after discharge.

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