Journal
PANCREAS
Volume 49, Issue 9, Pages 1161-1167Publisher
LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.1097/MPA.0000000000001637
Keywords
acute pancreatitis; epidemiology; etiology; severity; mortality
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Funding
- Applied Basic Research Program of Sichuan Provincial Science and Technology Department [2018JY0285]
- Luzhou Municipal People's Government-Southwest Medical University Science and Technology Strategic Cooperation Project [2018LZXNYD-ZK24]
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Objective The aim of this study was to evaluate the epidemiology, etiology, severity, and outcomes of acute pancreatitis (AP) in the southern Sichuan region of China. Methods All patients with first-attack AP between 2013 and 2018 in the Affiliated Hospital of Southwest Medical University were retrospectively identified. The etiology tendency was analyzed, and the relationship was defined with sex, aging, severity, length of stay, and mortality. Results Three thousand twenty-eight patients were enrolled for analysis. Acute biliary pancreatitis had the highest incidence rate; the second and third most common causes were hypertriglyceridemic (14.4%) and alcoholic (14.2%), followed by idiopathic (13.6%), mixed etiology (12.9%), and miscellaneous (2.31%). Patients with alcoholic AP were more likely to be middle-aged males, whereas patients with acute biliary pancreatitis were more likely to be elderly females (P< 0.05). The overall mortality in the hospital was 1%, and there was no difference in each etiological groups (P> 0.05). Conclusions Biliary disease was the predominant etiology of AP in southern Sichuan of China, and hypertriglyceridemia ranked second. The proportion of hypertriglyceridemic AP and mixed etiology AP gradually increased, whereas idiopathic AP decreased. There were different etiology proportion of AP according age, sex, and severity.
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