4.8 Article

Cross-Dehydrogenative Coupling of Strong C(sp3)-H with N-Heteroarenes through Visible-Light-Induced Energy Transfer

Journal

ORGANIC LETTERS
Volume 22, Issue 19, Pages 7709-7715

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/acs.orglett.0c02912

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Funding

  1. Natural Science Foundation of Heilongjiang Province [B2016008]
  2. National Natural Science Foundation of China [21502046]
  3. University Nursing Program for Young Scholars with Creative Talents in Heilongjiang Province [UNPYSCT2017124]

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The sustainable cross-dehydrogenative coupling of strong C(sp(3))-H with N-heteroarenes has been developed using an efficient organic photocatalyst. It features atomic- and step-economy, and acid-free conditions. Mechanism studies suggest a previous elusive energy transfer pathway from photocatalyst to N-heteroarenes and oxidants.

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