Journal
ORGANIC LETTERS
Volume 22, Issue 20, Pages 8086-8090Publisher
AMER CHEMICAL SOC
DOI: 10.1021/acs.orglett.0c03033
Keywords
-
Categories
Funding
- National Natural Science Foundation of China [22001188]
- Natural Science Foundation of Zhejiang Province [LQ19B020001]
- Project of Taizhou University Fund for Excellent Young Scholars
- Science and Technology Plan Project of Taizhou [1803gy04]
Ask authors/readers for more resources
The selective catalytic C-N bond cleavage of amides into value-added amine products is a desirable but challenging transformation. Molecules containing iminodibenzyl motifs are prevalent in pharmaceutical molecules and functional materials. Here we established a combined KOH/BEt3 catalyst for deaminative hydroboration of acyl-iminodibenzyl derivatives, including nonheterocyclic carboxamides, to the corresponding amines. This novel transition-metal-free methodology was also applied to the construction of Clomipramine and luminophores.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available