4.6 Letter

Intraoral atypical lentiginous melanocytic lesion in a pediatric patient

Journal

ORAL ONCOLOGY
Volume 112, Issue -, Pages -

Publisher

ELSEVIER
DOI: 10.1016/j.oraloncology.2020.105017

Keywords

Atypical lentiginous melanocytic hyperplasia; Atypical lentiginous melanocytic nevus; Melanocytic nevus; Melanoma; Oral cavity; Pediatric patient

Funding

  1. Coordenacao de Aperfeicoamento de Pessoal de Nivel Superior - Brasil (CAPES) [001]
  2. Sao Paulo Research Foundation (FAPESP) [2016/11419-0, 2018/18440-0]

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A rare case of intraoral atypical lentiginous melanocytic lesion affecting a pediatric patient was reported, diagnosed as lentiginous junctional melanocytic nevus with cytologic atypia. Excision is strongly recommended for melanocytic lesions showing features of atypical lentiginous growth pattern.
We present a rare case of intraoral atypical lentiginous melanocytic lesion affecting a pediatric patient, in which the diagnosis of lentiginous junctional melanocytic nevus with cytologic atypia was favored. The main differential diagnosis is lentiginous melanoma, which is a slowly progressing lesion, affecting mainly older adults, and microscopically presenting lentiginous growth pattern of moderately atypical melanocytes, with focal nesting and pagetoid spread. It is strongly recommended that melanocytic lesions showing features of atypical lentiginous growth pattern should be treated with wide excision; however, the impact of these guidelines on pediatric patients needs to be better defined with the report of further cases.

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