The Use of Speckle Correlation Analysis to Determine Blood Flow Velocity

Currently, optical methods based on the registration of speckle dynamics are widely used in modern diagnostics of the microvasculature. The results of the development of a laboratory model of a small-sized non-contact speckle sensor of the microvasculature and the experimental procedure are presented. A speckle sensor model for determining the blood flow velocity in the microvasculature is given, on the basis of which a prototype sensor can be created. The results of preliminary experimental studies of the possibility of blood microcirculation monitoring in the microvasculature using speckle correlation analysis are presented. A group of conditionally healthy volunteers aged 18 to 24 years was analyzed during the experiments. The obtained results correlate with the results presented in the literature on the value of the determined blood flow velocity. Problems and prospects of speckle correlation monitoring of the microvasculature in laboratory and clinical conditions are discussed.