Composition's effect ofOriganum Syriacumessential oils in the antimicrobial activities for the treatment of denture stomatitis

This research has several purposes: First to assess the bacterial and fungal minimum inhibitory concentration ofOriganum Syriacumessential oil. Second to quantify its bactericidal and fungicidal minimal concentration againstS. aureus,S. mutans, andC. albicansfound in denture stomatitis. The third purpose is to look at the influence of three different soils (Annaya, Bhanin and Michrif) on the essential oils composition. Three essential oils were extracted by hydro-distillation from three differentOriganum Syriacumplant origins. Bioassays were conducted using a broth microdilution methods. Gas Chromatography analysis was used to calculate the abundance of most components in each essential oil. Post hoc tests assessed antimicrobial effects between ecotypes while Pearson's test correlated the different components and their antimicrobial efficiency (alpha < 0.05). All tested essential oils were efficient against all microorganisms.Origanum Syriacumessential oils derived from Annaya and Bhanin soils showed a superior antimicrobial activity compared to the Michrif one. The most abundant component and most efficient among all essential oils constituents was carvacrol. It can be concluded thatOriganum Syriacumessential oils have an antimicrobial activity, which depends on the ecotype, its origin and its composition. They might be used to start a clinical trial for the treatment of denture stomatitis.

Automated summary

This research aimed to evaluate the antibacterial and antifungal properties of Origanum Syriacum essential oils, quantify their bactericidal and fungicidal minimal concentration against specific microorganisms, and explore the impact of different soils on essential oil composition. The study found that all tested essential oils were effective against microorganisms, with oils from Annaya and Bhanin soils exhibiting superior antimicrobial activity. The most abundant and efficient component in the oils was carvacrol, suggesting potential for clinical trials in treating denture stomatitis.