Journal
CRITICAL REVIEWS IN ENVIRONMENTAL SCIENCE AND TECHNOLOGY
Volume 46, Issue 19-20, Pages 1529-1583Publisher
TAYLOR & FRANCIS INC
DOI: 10.1080/10643389.2016.1245551
Keywords
Arsenic species; arsenic risk assessment; biomarker assessment; exposure pathways; integrated risk assessment; total arsenic
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Millions of people are exposed to arsenic resulting in a range of health implications. This paper provides an up-to-date review of the different sources of arsenic (water, soil, and food), indicators of human exposure (biomarker assessment of hair, nail, urine, and blood), epidemiological and toxicological studies on carcinogenic and noncarcinogenic health outcomes, and risk assessment approaches. The review demonstrates a need for more work evaluating the risks of different arsenic species such as, arsenate, arsenite monomethylarsonic acid, monomethylarsonous acid, dimethylarsinic acid, and dimethylarsinous acid as well as a need to better integrate the different exposure sources in risk assessments.
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