Related references
Note: Only part of the references are listed.The Ku70/80 ring in Non-Homologous End-Joining: easy to slip on, hard to remove
Birthe B. Kragelund et al.
FRONTIERS IN BIOSCIENCE-LANDMARK (2016)
Single-molecule imaging reveals the mechanism of Exo1 regulation by single-stranded DNA binding proteins
Logan R. Myler et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2016)
RECQL4 Promotes DNA End Resection in Repair of DNA Double-Strand Breaks
Huiming Lu et al.
CELL REPORTS (2016)
Candidate gene analysis of BRCA1/2 mutation-negative high-risk Russian breast cancer patients
Anna P. Sokolenko et al.
CANCER LETTERS (2015)
Common variants at the CHEK2 gene locus and risk of epithelial ovarian cancer
Kate Lawrenson et al.
CARCINOGENESIS (2015)
Sumoylation regulates EXO1 stability and processing of DNA damage
Serena Bologna et al.
CELL CYCLE (2015)
Poly(ADP-ribose)-binding promotes Exo1 damage recruitment and suppresses its nuclease activities
Abigael Cheruiyot et al.
DNA REPAIR (2015)
Association between genetic polymorphisms in DNA mismatch repair-related genes with risk and prognosis of head and neck squamous cell carcinoma
Guilherme Augusto Silva Nogueira et al.
INTERNATIONAL JOURNAL OF CANCER (2015)
14-3-3 Proteins Restrain the Exo1 Nuclease to Prevent Overresection
Xiaoqing Chen et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2015)
Quantitative Proteomic Atlas of Ubiquitination and Acetylation in the DNA Damage Response
Andrew E. H. Elia et al.
MOLECULAR CELL (2015)
Genome-wide association analysis of more than 120,000 individuals identifies 15 new susceptibility loci for breast cancer
Kyriaki Michailidou et al.
NATURE GENETICS (2015)
The 9-1-1 checkpoint clamp coordinates resection at DNA double strand breaks
Greg H. P. Ngo et al.
NUCLEIC ACIDS RESEARCH (2015)
EXO1 is critical for embryogenesis and the DNA damage response in mice with a hypomorphic Nbs1 allele
Katrin Rein et al.
NUCLEIC ACIDS RESEARCH (2015)
The PIN domain of EXO1 recognizes poly(ADP-ribose) in DNA damage response
Feng Zhang et al.
NUCLEIC ACIDS RESEARCH (2015)
Functional Interplay between the 53BP1-Ortholog Rad9 and the Mre11 Complex Regulates Resection, End-Tethering and Repair of a Double-Strand Break
Matteo Ferrari et al.
PLOS GENETICS (2015)
Poly(ADP-ribosyl)ation in regulation of chromatin structure and the DNA damage response
Michael Tallis et al.
CHROMOSOMA (2014)
DNA Double-strand Break Repair in a Cellular Context
A. Shibata et al.
CLINICAL ONCOLOGY (2014)
The role of RecQ helicases in non-homologous end-joining
Guido Keijzers et al.
CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY (2014)
Exo1 independent DNA mismatch repair involves multiple compensatory nucleases
Amar Desai et al.
DNA REPAIR (2014)
Mlh1-Mlh3, a Meiotic Crossover and DNA Mismatch Repair Factor, Is a Msh2-Msh3-stimulated Endonuclease
Maria V. Rogacheva et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2014)
DNA2 Cooperates with the WRN and BLM RecQ Helicases to Mediate Long-range DNA End Resection in Human Cells
Andreas Sturzenegger et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2014)
Biochemical characterization of a cancer-associated E109K missense variant of human exonuclease 1
Stephanie Bregenhorn et al.
NUCLEIC ACIDS RESEARCH (2014)
Hydrolytic function of Exo1 in mammalian mismatch repair
Hongbing Shao et al.
NUCLEIC ACIDS RESEARCH (2014)
The 9-1-1 checkpoint clamp stimulates DNA resection by Dna2-Sgs1 and Exo1
Greg H. P. Ngo et al.
NUCLEIC ACIDS RESEARCH (2014)
Exonuclease 1 is essential for maintaining genomic stability and the proliferative capacity of neural but not hematopoietic stem cells
Junling Zhang et al.
STEM CELL RESEARCH (2014)
Phosphorylation of EXO1 by CDKs 1 and 2 regulates DNA end resection and repair pathway choice
Nozomi Tomimatsu et al.
NATURE COMMUNICATIONS (2014)
Genetically engineered mouse models for functional studies of SKP1-CUL1-F-box-protein (SCF) E3 ubiquitin ligases
Weihua Zhou et al.
CELL RESEARCH (2013)
The SOSS1 single-stranded DNA binding complex promotes DNA end resection in concert with Exo1
Soo-Hyun Yang et al.
EMBO JOURNAL (2013)
Noncanonical Role of the 9-1-1 Clamp in the Error-Free DNA Damage Tolerance Pathway
Georgios Ioannis Karras et al.
MOLECULAR CELL (2013)
RPA Coordinates DNA End Resection and Prevents Formation of DNA Hairpins
Huan Chen et al.
MOLECULAR CELL (2013)
PCNA promotes processive DNA end resection by Exo1
Xiaoqing Chen et al.
NUCLEIC ACIDS RESEARCH (2013)
Breast Tumors with Elevated Expression of 1q Candidate Genes Confer Poor Clinical Outcome and Sensitivity to Ras/PI3K Inhibition
Muthulakshmi Muthuswami et al.
PLOS ONE (2013)
Mammalian Exo1 encodes both structural and catalytic functions that play distinct roles in essential biological processes
Sonja Schaetzlein et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
Microhomology-mediated End Joining and Homologous Recombination share the initial end resection step to repair DNA double-strand breaks in mammalian cells
Lan N. Truong et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
Telomeric 3′ Overhangs Derive from Resection by Exo1 and Apollo and Fill-In by POT1b-Associated CST
Peng Wu et al.
CELL (2012)
14-3-3 checkpoint regulatory proteins interact specifically with DNA repair protein human exonuclease 1 (hEXO1) via a semi-conserved motif
Sofie Dabros Andersen et al.
DNA REPAIR (2012)
Human Ku70/80 Protein Blocks Exonuclease 1-mediated DNA Resection in the Presence of Human Mre11 or Mre11/Rad50 Protein Complex
Jingxin Sun et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2012)
Differential regulation of RNF8-mediated Lys48-and Lys63-based poly-ubiquitylation
Gabriel Tsz-Mei Lok et al.
NUCLEIC ACIDS RESEARCH (2012)
Separable roles for Exonuclease I in meiotic DNA double-strand break repair
Rebecca E. Keelagher et al.
DNA REPAIR (2011)
Bi-directional routing of DNA mismatch repair protein human exonuclease 1 to replication foci and DNA double strand breaks
Sascha E. Liberti et al.
DNA REPAIR (2011)
PARP-1 enhances the mismatch-dependence of 5'-directed excision in human mismatch repair in vitro
Yiyong Liu et al.
DNA REPAIR (2011)
BLM-DNA2-RPA-MRN and EXO1-BLM-RPA-MRN constitute two DNA end resection machineries for human DNA break repair
Amitabh V. Nimonkar et al.
GENES & DEVELOPMENT (2011)
Mismatch Repair Proteins MSH2, MLH1, and EXO1 Are Important for Class-Switch Recombination Events Occurring in B Cells That Lack Nonhomologous End Joining
Jennifer Eccleston et al.
JOURNAL OF IMMUNOLOGY (2011)
Functional Interplay of the Mre11 Nuclease and Ku in the Response to Replication-Associated DNA Damage
Steven S. Foster et al.
MOLECULAR AND CELLULAR BIOLOGY (2011)
14-3-3 Proteins Regulate Exonuclease 1-Dependent Processing of Stalled Replication Forks
Kim Engels et al.
PLOS GENETICS (2011)
Delineation of WRN helicase function with EXO1 in the replicational stress response
Monika Aggarwal et al.
DNA REPAIR (2010)
Pif1- and Exo1-dependent nucleases coordinate checkpoint activation following telomere uncapping
James M. Dewar et al.
EMBO JOURNAL (2010)
Saccharomyces cerevisiae Mre11/Rad50/Xrs2 and Ku proteins regulate association of Exo1 and Dna2 with DNA breaks
Eun Yong Shim et al.
EMBO JOURNAL (2010)
DNA end resection by CtIP and exonuclease 1 prevents genomic instability
Wassim Eid et al.
EMBO REPORTS (2010)
Temporally and Biochemically Distinct Activities of Exo1 during Meiosis: Double-Strand Break Resection and Resolution of Double Holliday Junctions
Kseniya Zakharyevich et al.
MOLECULAR CELL (2010)
Synthesis-dependent microhomology-mediated end joining accounts for multiple types of repair junctions
Amy Marie et al.
NUCLEIC ACIDS RESEARCH (2010)
Phosphorylation of Exo1 modulates homologous recombination repair of DNA double-strand breaks
Emma Bolderson et al.
NUCLEIC ACIDS RESEARCH (2010)
Survival and Growth of Yeast without Telomere Capping by Cdc13 in the Absence of Sgs1, Exo1, and Rad9
Hien-Ping Ngo et al.
PLOS GENETICS (2010)
Sgs1 and Exo1 Redundantly Inhibit Break-Induced Replication and De Novo Telomere Addition at Broken Chromosome Ends
John R. Lydeard et al.
PLOS GENETICS (2010)
Class Switch Recombination Efficiency and Junction Microhomology Patterns in Msh2-, Mlh1-, and Exo1-Deficient Mice Depend on the Presence of μ Switch Region Tandem Repeats
Jennifer Eccleston et al.
JOURNAL OF IMMUNOLOGY (2009)
Telomere Shortening in Neural Stem Cells Disrupts Neuronal Differentiation and Neuritogenesis
Sacri R. Ferron et al.
JOURNAL OF NEUROSCIENCE (2009)
Non-homologous end joining in class switch recombination: the beginning of the end
Ashwin Kotnis et al.
PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES (2009)
Ctp1 and Exonuclease 1, alternative nucleases regulated by the MRN complex, are required for efficient meiotic recombination
Joseph A. Farah et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
A possible mechanism for exonuclease 1-independent eukaryotic mismatch repair
Farid A. Kadyrov et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
Flexibility of Eukaryotic Okazaki Fragment Maturation through Regulated Strand Displacement Synthesis
Carrie M. Stith et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
Sae2, Exo1 and Sgs1 collaborate in DNA double-strand break processing
Eleni P. Mimitou et al.
NATURE (2008)
DNA mismatch repair: Molecular mechanism, cancer, and ageing
Peggy Hsieh et al.
MECHANISMS OF AGEING AND DEVELOPMENT (2008)
Identification of the Xenopus DNA2 protein as a major nuclease for the 53 strand-specific processing of DNA ends
Shuren Liao et al.
NUCLEIC ACIDS RESEARCH (2008)
Proteome-wide identification of poly(ADP-ribose) binding proteins and poly(ADP-ribose)-associated protein complexes
Jean-Philippe Gagne et al.
NUCLEIC ACIDS RESEARCH (2008)
Human exonuclease 1 and BLM helicase interact to resect DNA and initiate DNA repair
Almitabh V. Nimonkar et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
ATR-dependent pathways control hEXO1 stability in response to stalled forks
Mahmoud El-Shemerly et al.
NUCLEIC ACIDS RESEARCH (2008)
A mutation in EXO1 defines separable roles in DNA mismatch repair and post-replication repair
Phuoc T. Tran et al.
DNA REPAIR (2007)
Exonuclease-1 deletion impairs DNA damage signaling and prolongs lifespan of telomere-dysfunctional mice
Sonja Schaetzlein et al.
CELL (2007)
Reconstituted Okazaki fragment processing indicates two pathways of primer removal
Marie L. Rossi et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
RECQ1 helicase interacts with human mismatch repair factors that regulate genetic recombination
KM Doherty et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Mutation in Rpa1 results in defective DNA double-strand break repair, chromosomal instability and cancer in mice
YX Wang et al.
NATURE GENETICS (2005)
hMRE11 deficiency leads to microsatellite instability and defective DNA mismatch repair
AT Vo et al.
EMBO REPORTS (2005)
Degradation of human exonuclease 1b upon DNA synthesis inhibition
M El-Shemerly et al.
CANCER RESEARCH (2005)
Single nucleotide polymorphisms in the EXO1 gene and risk of colorectal cancer in a Japanese population
H Yamamoto et al.
CARCINOGENESIS (2005)
Oxidative damage in telomeric DNA disrupts recognition by TRF1 and TRF2
PL Opresko et al.
NUCLEIC ACIDS RESEARCH (2005)
EXO1 contributes to telomere maintenance in both telomerase-proficient and telomerase-deficient Saccharomyces cerevisiae
AA Bertuch et al.
GENETICS (2004)
EXO1 plays a role in generating type I and type II survivors in budding yeast
L Maringele et al.
GENETICS (2004)
T-loops and the origin of telomeres
T de Lange
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2004)
Characterization of human exonuclease 1 in complex with mismatch repair proteins, subcellular localization and association with PCNA
FC Nielsen et al.
ONCOGENE (2004)
Altered somatic hypermutation and reduced class-switch recombination in exonuclease 1-mutant mice
PD Bardwell et al.
NATURE IMMUNOLOGY (2004)
Aging results in reduced epidermal growth factor receptor signaling, diminished olfactory neurogenesis, and deficits in fine olfactory discrimination
E Enwere et al.
JOURNAL OF NEUROSCIENCE (2004)
Accumulation of mutations and somatic selection in aging neural stem/progenitor cells
KJ Bailey et al.
AGING CELL (2004)
The Mre11 nuclease is not required for 5′ to 3′ resection at multiple HO-induced double-strand breaks
B Llorente et al.
MOLECULAR AND CELLULAR BIOLOGY (2004)
End resection initiates genomic instability in the absence of telomerase
JA Hackett et al.
MOLECULAR AND CELLULAR BIOLOGY (2003)
Germline deletions of EXO1 do not cause colorectal tumors and lesions which are null for EXO1 do not have microsatellite instability
NA Alam et al.
CANCER GENETICS AND CYTOGENETICS (2003)
The exonucleolytic and endonucleolytic cleavage activities of human exonuclease 1 are stimulated by an interaction with the carboxyl-terminal region of the Werner syndrome protein
S Sharma et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Inactivation of Exonuclease 1 in mice results in DNA mismatch repair defects, increased cancer susceptibility, and male and female sterility
KC Wei et al.
GENES & DEVELOPMENT (2003)
Mechanism of 5 '-directed excision in human mismatch repair
J Genschel et al.
MOLECULAR CELL (2003)
Yeast Mre11 and Rad1 proteins define a Ku-independent mechanism to repair double-strand breaks lacking overlapping end sequences
JL Ma et al.
MOLECULAR AND CELLULAR BIOLOGY (2003)
Telomere-binding protein TRF2 binds to and stimulates the Werner and Bloom syndrome helicases
PL Opresko et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Identification of telomere-dependent senescence-like arrest in mouse embryonic fibroblasts
S Espejel et al.
EXPERIMENTAL CELL RESEARCH (2002)
A murine model of Nijmegen breakage syndrome
BR Williams et al.
CURRENT BIOLOGY (2002)
Human exonuclease I is required for 5′ and 3′ mismatch repair.
J Genschel et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
The interaction of DNA mismatch repair proteins with human exonuclease I
C Schmutte et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
exo1-Dependent mutator mutations:: Model system for studying functional interactions in mismatch repair
NS Amin et al.
MOLECULAR AND CELLULAR BIOLOGY (2001)
HNPCC mutations in the human DNA mismatch repair gene hMLH1 influence assembly of hMutLα and hMLH1-hEXO1 complexes
AC Jäger et al.
ONCOGENE (2001)
Germline mutations of EXO1 gene in patients with hereditary nonpolyposis colorectal cancer (HNPCC) and atypical HNPCC forms
Y Wu et al.
GASTROENTEROLOGY (2001)
Exo1 roles for repair of DNA double-strand breaks and meiotic crossing over in Saccharomyces cerevisiae
H Tsubouchi et al.
MOLECULAR BIOLOGY OF THE CELL (2000)
Identification of factors interacting with hMSH2 in the fetal liver utilizing the yeast two-hybrid system - In vivo interaction through the C-terminal domains of hEXO1 and hMSH2 and comparative expression analysis
LJ Rasmussen et al.
MUTATION RESEARCH-DNA REPAIR (2000)