Detection of human auditory evoked brain signals with a resilient nonlinear optically pumped magnetometer

Optically Pumped Magnetometers (OPMs) have been hailed as the future of human magnetoencephalography, as they enable a level of flexibility and adaptability that cannot be obtained with systems based on superconductors. While OPM sensors are already commercially available, there is plenty of room for further improvements and customization. In this work, we detected auditory evoked brain fields using an OPM based on the nonlinear magneto-optical rotation (NMOR) technique. Our sensor head, containing only optical and non-magnetizable elements, is connected to an external module including all the electronic components, placed outside the magnetically shielded room. The use of the NMOR allowed us to detect the brain signals in non-zero magnetic field environments. In particular, we were able to detect auditory evoked fields in a background field of 70 nT. We benchmarked our sensor with conventional SQUID sensors, showing comparable performance. We further demonstrated that our sensor can be employed to detect modulations of brain oscillations in the alpha band. Our results are a promising stepping-stone towards the realization of resilient OPM-based magnetoencephalography systems that do not require active compensation.

Automated summary

Optically Pumped Magnetometers (OPMs) are considered the future of human magnetoencephalography due to their flexibility and adaptability. This study detected auditory evoked brain fields using an OPM based on the nonlinear magneto-optical rotation (NMOR) technique, showcasing excellent performance in non-zero magnetic field environments. Our results demonstrate promising progress towards resilient OPM-based magnetoencephalography systems.